Pesticide Registration Guidance and Related Links
The Pesticide Registration Improvement Act of 2022 (PRIA 5), enacted on December 29, 2022, specifies that not later than 180 days after enactment, the EPA shall post on a single webpage aggregated information on pesticide regulation under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), including:
- All guidance relating to risk assessment, risk mitigation, benefits assessments, and cost-benefit balancing;
- Hyperlinks to resources, including the Department of Agriculture's “national list of allowed and prohibited substances” for organic crop and livestock production;
- Biopesticides and pesticides exempt pursuant to section 25(b) of FIFRA; and
- Integrated pest management principles developed under section 28(c) of FIFRA, including technical assistance for implementation of those principles.
In response to this requirement, EPA is providing the following guidance documents and pesticide-related links. EPA will continue to update this webpage with additional guidance as it becomes available.
Pesticide-related guidance:
This table displays a list of pesticide-related guidance documents issued by the Office of Chemical Safety and Pollution Prevention and addresses requirement 1 above. EPA's guidance documents lack the force and effect of law, unless expressly authorized by statute or incorporated into a contract.
| Document Name (click on link to view) |
Date | Identifier | Topic | Description/Summary | ID |
|---|---|---|---|---|---|
| Antimicrobial Pesticide Registration | 2019-04-04 | EPA 705-G-2020-0414 | Pesticide Registration | Resources for an individual or company wanting to register an antimicrobial pesticide. | 11 |
| Pesticide Registration Manual: Chapter 4 - Additional Considerations for Antimicrobial Products | 2019-10-28 | EPA 705-G-2020-0502 | FIFRA, Antimicrobial | This chapter provides additional guidance unique to antimicrobial pesticides that is not covered in the other chapters. | 78 |
| Methods and Guidance for Testing the Efficacy of Antimicrobial Products Against Spores of Clostridium difficile on Hard Non-Porous Surfaces (February 2018) | 2019-02-25 | EPA 705-G-2020-1261 | FIFRA, Antimicrobial | This document provides an update to the Agency’s interim guidance for the efficacy evaluation of antimicrobial pesticides that are labeled for treating hard non-porous surfaces in healthcare settings contaminated with spores of Clostridium difficile. | 72 |
| EPA Data Requirements for Registration of Antimicrobial Pesticides: Part 158W | 2019-05-03 | EPA 705-G-2020-1262 | Pesticide Registration; FIFRA; Pesticides; Antimicrobial; | This document gives the data requirements for antimicrobial products. | 40 |
| EPA Data Requirements for Registration of Antimicrobial Pesticides: 158W Implementation Letter | 2017-05-05 | EPA 705-G-2020-1264 | Pesticide Registration | This letter informs pesticide registrants how EPA has been implementing new data requirements under 40 CFR Part 158W. | 39 |
| Alternate Testing Framework for Classification of Eye Irritation Potential of EPA-Regulated Pesticide Products | 2017-05-24 | EPA 705-G-2020-1272 | Pesticide Registration | EPA has updated guidance on testing antimicrobial cleaning products for potential eye irritation. This guidance relies on non-animal testing and expands the use of certain tests. | 9 |
| How to Apply for the DfE Logo for Antimicrobial Pesticide Products | 2019-05-21 | EPA 705-G-2020-1297 | FIFRA; Pesticides; Antimicrobial; | This document explains how to apply for a designed for the environment logo on AD products. | 65 |
| Adding the NSF Logo to Antimicrobial Product Labels | 2016-09-09 | EPA 705-G-2020-1298 | Pesticide Labels | Upon receipt of certification from NSF, a registrant may submit a request to add the logo via the Agency’s notification process as described in PR Notice 98-10. | 8 |
| Use of the Term "Germs" on Antimicrobial Labels | 2005-01-05 | EPA 705-G-2020-1302 | FIFRA; Pesticides; Antimicrobial; | EPA response letter to CSPA providing guidance on when the term “germs” can be used on an antimicrobial label. | 115 |
| Indirect Dietary Residential Exposure Assessment Model (IDREAM) Implementation | 2019-09-05 | EPA 705-G-2020-1345 | FIFRA, Antimicrobial | The Indirect Dietary Residential Exposure Assessment Model (IDREAM) estimates indirect ingestion exposure to disinfectants used in residential settings on hard surfaces where there may be inadvertent transfer to edible items prepared on those surfaces. | 66 |
| Surface Safety Claims Guidance Letter | 2016-03-24 | EPA 705-G-2020-1455 | FIFRA; Pesticides; Antimicrobial; | This letter provides guidance on the use of surface safety claims on antimicrobial product labeling. | 108 |
| Protocol for Room Sterilization by Fogger Application | 2016-09-26 | EPA 705-G-2020-1457 | FIFRA, Antimicrobial | This protocol describes an end-use fogging application for sterilizing porous and non-porous surfaces within a sealed and enclosed space. | 92 |
| Efficacy Testing Standards for Antimicrobial Product Data Call-In Responses | 2017-05-11 | EPA 705-G-2020-1458 | FIFRA, Antimicrobial | One of the objectives of reregistration is for the Agency to ensure that antimicrobial pesticide products are supported by acceptable efficacy data. Find out about the standards data must meet for antimicrobial products subject to reregistration. | 35 |
| Guidance to Companies on Referring to Registered Disinfectant Products that Meet the CDC Criteria for Use Against the Ebola Virus | 2017-10-13 | EPA 705-G-2020-1459 | FIFRA; Pesticides; Antimicrobial; | There are no EPA-registered products with label claims against the Ebola virus, but enveloped viruses such as Ebola are susceptible to many hospital disinfectants used to disinfect hard, non-porous surfaces. CDC guidance addresses use of such products. | 61 |
| Guidance to Companies on Referring to Registered Disinfectant (Enterovirus D68) | 2019-05-13 | EPA 705-G-2020-1460 | FIFRA, Antimicrobial | EPA has worked closely with Center for Disease Control (CDC) to develop the CDC recommendations for environmental infection control in healthcare settings against Enterovirus D68 (EV-D68). | 60 |
| Fogger and Mister Final Signed Letter | 2013-04-01 | EPA 705-G-2020-1461 | Pesticide Registration | EPA has asked pesticide companies to provide data or amend registrations of products claiming to control public health microorganisms when applied by fogging and/or misting methods. The letter further describes the ways in which the company may respond. | 42 |
| Antimicrobials Used in the Fermentation of Fuel Ethanol – Clarification of Jurisdiction | 2016-11-02 | EPA 705-G-2020-1462 | FIFRA; Pesticides; Antimicrobial; | EPA has determined that antimicrobials applied to processed food or feed during fermentation of organic material to produce fuel ethanol are outside the scope of EPA’s regulatory authority under FIFRA. The Food and Drug Administration has jurisdiction. | 18 |
| Guidance for Use of Food-Grade Shell-Egg Sanitizers | 2016-11-02 | EPA 705-G-2020-1463 | FIFRA; Pesticides; Antimicrobial; | Formulations must be cleared under 21 CFR 178.1010 as sanitizing solutions for food contact surfaces or have a tolerance or exemption from the requirement of a tolerance in 40 CFR Part 180 that covers use as a sanitizing solution for food contact surfaces. | 54 |
| Protocols for Testing the Efficacy of Disinfectants Against Hepatitis B Virus (HBV) | 2018-04-02 | EPA 705-G-2020-1464 | FIFRA, Antimicrobial | EPA has endorsed the in vitro (test tube) duck assay as the appropriate and preferred alternative to animal testing. | 93 |
| Use of Disinfectants and Sanitizers in Heating, Ventilation, Air Conditioning, and Refrigeration Systems | 2010-09-20 | EPA 705-G-2020-1465 | FIFRA; Pesticides; Antimicrobial; | This document brings attention several concerns that the Agency has regarding the use of sanitizer and/or disinfectant products, and other types of antimicrobial products, to treat the surfaces of heating, ventilation | 114 |
| Consideration of Prions as a Pest under FIFRA | 2003-09-10 | EPA 705-G-2020-1467 | FIFRA, Antimicrobial | This is the record of decision regarding prions should be considered to be a “pest” the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended. It includes information about EPA regulation of pesticides based on this decision. | 25 |
| Protocol for Residual Self-Sanitizing Activity of Dried Chemical Residues on Hard, Non-Porous Surfaces | 2016-09-26 | EPA 705-G-2020-1471 | FIFRA, Antimicrobial | This protocol can be used to determine the residual sanitizing efficacy of antimicrobial products after application to inanimate, nonporous, non-food contact hard surfaces. | 91 |
| Updated Draft Protocol for the Evaluation of Bactericidal Activity of Hard, Non-porous Copper Containing Surface Products | 2016-01-27 | EPA 705-G-2020-1472 | FIFRA, Antimicrobial | This document describes the updated draft testing protocol recommended by the EPA to support the registration of copper-containing surface products (such as door knobs, or other items that are not intended for food contact) that bear sanitizer claims. | 113 |
| Guidance to Registrants: Process for Making Claims Against Emerging Viral Pathogens not on EPA-Registered Disinfectant Labels | 2017-10-03 | EPA 705-G-2020-1474 | FIFRA, Antimicrobial | This guidance proposes to use an organism hierarchy to identify effective products for use with emerging pathogens and to permit registrants to make limited statements against such pathogens. It provides general guidance to interested parties. | 62 |
| Guidance for Pre-Application Meetings on New Active Ingredients, Major New Uses and Other Registration Actions | 2019-09-05 | EPA 705-G-2020-1479 | Pesticide Registration | This is to provide guidance to OPP/AD staff concerning meetings with companies that are considering submitting an application involving a new active ingredient, new use, new technology. | 47 |
| Antimicrobial Policy and Guidance Documents | 2017-09-26 | EPA 705-G-2020-1486 | Pesticide Registration | These policies and guidance resources are intended to assist companies that want to register an antimicrobial pesticide. | 13 |
| Review Process for the Registration and Use Directions for Floor Wipe Towelette Products | 2016-12-06 | EPA 705-G-2020-1492 | FIFRA, Antimicrobial | This guidance provides Antimicrobials Division staff with guidance related to the registration requirements and use directions for presaturated/impregnated floor wipe towelette products. This document will be used for new and existing wipe registrations. | 98 |
| Emerging Viral Pathogen Guidance for Antimicrobial Pesticides | 2017-07-31 | EPA 705-G-2020-1519 | Pesticide Registration | The guidance outlines a voluntary, two stage process involving product label amendments and modified terms of registration and applies only to emerging viruses. | 38 |
| Mixtures Equation Pilot Program to Reduce Animal Testing | 2017-05-10 | EPA 705-G-2020-1639 | FIFRA, Antimicrobial | EPA is announcing the start of a pilot program to evaluate the usefulness and acceptability of a mathematical tool (the GHS Mixtures Equation), which is used in the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). | 73 |
| Antimicrobial Testing Methods & Procedures: MB-35-00 | 2017-03-21 | EPA 705-G-2020-1667 | Pesticide Analytical Methods | Information about ATMP - OECD Quantitative Method for Evaluating the Efficacy of Liquid Antimicrobials against Candida auris on Hard, Non-Porous Surfaces - MB-35-00 | 16 |
| Interim Guidance for the Efficacy Evaluation of Products for Claims against Candida auris | 2017-05-24 | EPA 705-G-2020-1668 | FIFRA, Antimicrobial | EPA has developed two new test methods and associated testing guidance for evaluating the effectiveness of antimicrobial pesticides against Candida auris (C. auris). | 67 |
| Methods and Guidance for Testing the Efficacy of Antimicrobial Products Against Biofilms on Hard, Non-Porous Surfaces | 2017-10-19 | EPA 705-G-2020-1702 | FIFRA, Antimicrobial | Guidance document to assess the efficacy of antimicrobial pesticides hard non-porous surfaces. | 71 |
| Guidance on Disinfectant Products Intended to Treat Drinking Water | 2017-10-17 | EPA 705-G-2020-1712 | FIFRA, Antimicrobial | Guidance provides a basic overview of FIFRA product registration process and how FIFRA approval relates to the Safe Drinking Water Act, specifically for disinfectant products intended to treat. | 58 |
| New EPA Quick Guide for Registering Disinfectant Products for Drinking Water Use | 2017-10-17 | EPA 705-G-2020-1715 | FIFRA, Antimicrobial | Developed this Quick Guide for Disinfectant Products for Drinking Water Use in response to requests to help prospective pesticide registrants gain a basic understanding of the FIFRA. | 74 |
| Label Guidance for Antimicrobial Pesticides Used for Poultry House Disinfection | 1980-01-17 | EPA 705-G-2020-2342 | FIFRA, Antimicrobial | The purpose of this guidance is to outline the use directions for antimicrobial pesticides used in poultry houses. | 69 |
| 875.1700 Product Use Information (Applicator) | 1996-02-01 | EPA 705-G-2020-2365 | FIFRA, Pesticides, Antimicrobial | This document explains pest use information. | 3 |
| 875.2300 Indoor Surface Residue Dissipation | 1998-02-10 | EPA 705-G-2020-2366 | FIFRA, Pesticides, Antimicrobial | This document explains indoor surface residue test guidelines. | 4 |
| 875.2700 Product Use Information (Post Application) | 1998-02-10 | EPA 705-G-2020-2367 | FIFRA, Pesticides, Antimicrobial | This document explains the guidelines for product use information. | 5 |
| 875.2800 Descriptions of Human Activity. | 2009-07-30 | EPA 705-G-2020-2368 | FIFRA, Pesticides, Antimicrobial | This document explains the description of human activities testing guidelines. | 6 |
| Guidance for Waiving or Bridging of Mammalian Acute Toxicity Tests for Pesticides and Pesticide Products (Acute Oral, Acute Dermal, Acute Inhalation, Primary Eye, Primary Dermal, and Dermal Sensitization) | 2012-03-01 | EPA 705-G-2020-2376 | FIFRA, Antimicrobial | This document gives information on waiving or bridging acute tox data (master) | 57 |
| Guidance for quantitative assessment of dermal sensitization risk for pesticide chemicals in the Office of Pesticide Programs | 2019-09-04 | EPA 705-G-2020-2377 | FIFRA, Antimicrobial | This document explains assessment of dermal sensitization. | 48 |
| Label Guidance for Antimicrobial Pesticides on Hard, Non-Porous Surfaces | 1979-12-02 | EPA 705-G-2020-2379 | FIFRA, Antimicrobial | This document provides information on products used on hard non-porous surfaces. | 68 |
| Guidance Document Label Claims for Products with ATP failures | 2018-12-10 | EPA 705-G-2020-2386 | FIFRA, Antimicrobial | Master, this document explains label guidance for ATP failures | 45 |
| Guidance for Reregistration of Pesticide Products Containing Chlorinated Isocyanurates as the Active Ingredient | 1992-09-01 | EPA 705-G-2020-2388 | FIFRA, Antimicrobial | This gives guidance for products containing chlorinated isocyanurates. | 49 |
| Guidance For The Reregistration Of Wood Preservative Pesticide Products Containing Chromated And Non-Chromated Arsenicals as the Active Ingredient, Case Number 0647 | 1986-09-10 | EPA 705-G-2020-2391 | FIFRA, Antimicrobial | This document gives information for reregistration of chromated and non-chromated arsenicals. | 53 |
| Draft Guidance on Conducting an Ecological Exposure Assessment for Antifoulant Coatings & Paints— Saltwater Marinas. June 2016 | 2016-06-01 | EPA 705-G-2020-2392 | marinas, antifoulants, copper, FIFRA | SOP for estimating exposures for antifoulant paints in coastal marinas. Master | 32 |
| E-FAST, Down the Drain Assessment Model | 2007-10-01 | EPA 705-G-2020-2394 | down the drain, WWTP, wastewater, E-FAST, FIFRA | Model developed by OPPT and used by AD to estimate aquatic exposures from pesticidal chemicals which are disposed of down the drain either in municipal or industrial waste water systems. Manual updated in 2015. Master | 34 |
| Reregistration Eligibility Document Sodium and Calcium Hypochlorite Salts | 1992-02-01 | EPA 705-G-2020-2395 | FIFRA, Antimicrobial | RED for Sodium and Calcium hypochlorite (aka bleach) | 96 |
| Guidance for Reregistration of Pesticides containing Sodium and Calcium Hypochlorite Salts as the Active Ingredient | 1986-02-01 | EPA 705-G-2020-2396 | FIFRA, Antimicrobial | The 1986 standard for Sodium and Calcium hypochlorite | 50 |
| Series 860 Residue Chemistry Guidelines | 2016-08-25 | EPA 705-G-2020-2563 | FIFRA, Antimicrobial | This document describes the residue chemistry guidelines for dietary analysis | 102 |
| 870 Toxicology Guidelines | 2019-12-12 | EPA 705-G-2020-2564 | FIFRA, Pesticides, Antimicrobial | This document explains the toxicology guidelines. | 1 |
| 875 Exposure Guidelines | 2016-08-25 | EPA 705-G-2020-2565 | FIFRA, Pesticides, Antimicrobial | This document explains the exposure guidelines. | 2 |
| Label Guidance for Antimicrobial Pesticides Used for Sanitation of Food Contact Surfaces | 1979-12-02 | EPA 705-G-2020-2581 | FIFRA, Antimicrobial | This document gives information on sanitizing food contact surfaces | 70 |
| Efficacy Testing Standards for Reregistration | 2017-05-11 | EPA 705-G-2020-2597 | data-call-in; reregistration | This document provides an overview of the 2014 efficacy data standards and identifies certain testing standards that differ from the 2012 Guidelines. It is intended for registrants citing/submitting previously generated or new efficacy data in response to a reregistration data call-in | 36 |
| UDM Performance Standard Revision Document | 2013-11-26 | EPA 705-G-2020-2598 | FIFRA, Antimicrobial | Explanation of changes to Use Dilution Method (UDM) | 112 |
| Crosswalk Table for Non-Public Health Guidelines | 2007-05-23 | EPA 705-G-2020-2599 | FIFRA, Antimicrobial | Determination of non-public guidelines for organisms, archived page but still good | 28 |
| Fragrance Notification Programs | 2015-12-01 | EPA 705-G-2020-2600 | FIFRA, Antimicrobial | This document provides guidance for EPA's Office of Pesticide Programs (OPP) Fragrance Notification Program (PFNP) for registrants seeking to add or modify existing fragrances in new or currently registered pesticide products. | 43 |
| Guidelines for Voluntary Disclosure of Antimicrobial Ingredient Information on Company Websites and/or Labels | 2019-03-28 | EPA 705-G-2020-2601 | FIFRA, Antimicrobial | This document gives information on inert disclosure | 64 |
| Guidance for Testing and Labeling Claims against Pandemic 2009 H1N1 Influenza A Virus (formerly called Swine Flu) | 2017-07-21 | EPA 705-G-2020-2603 | FIFRA, Antimicrobial | This document gives information on claims about 2009 pandemic flu. | 51 |
| Response to questions concerning existing C. diff claims (vegetative form) on antimicrobial product labels | 2008-09-22 | EPA 705-G-2020-2605 | FIFRA, Antimicrobial | This document is a response to questions about C. diff claims | 97 |
| Barrier Products Clarification Document--Guidance for what is needed for an Agency barrier determination | 2007-03-01 | EPA 705-G-2020-2606 | FIFRA, Antimicrobial | This document provides information on what is considered a barrier | 19 |
| Use of the term "shock" on non-pesticide labeling | 2008-07-24 | EPA 705-G-2020-2607 | FIFRA, Antimicrobial | This document explains how the term shock is used on non-pesticidal labeling. | 116 |
| Antimicrobial Products Registered for Disinfection Use against Avian Influenza on Poultry Farms and Other Facilities | 2019-12-18 | EPA 705-G-2020-2608 | FIFRA, Antimicrobial | This document provides guidance on the avian on use of antimicrobial products in poultry farms and other facilities. | 14 |
| Draft Interim Guidance for Non-Residual Sanitizers on Hard, Inanimate Food Contact Surfaces Using Pre-Saturated Towelettes | 2001-04-12 | EPA 705-G-2020-2613 | FIFRA, Antimicrobial | This protocol can be used to conduct efficacy testing to support a pre-saturated towelette registration for use on food contact surfaces. | 33 |
| BISM JWOD & Skilkraft Letter | 2004-07-26 | EPA 705-G-2020-2614 | FIFRA, Antimicrobial | This letter explains the use of logos, the website is archived | 20 |
| Consumer Specialty Products Association (CSPA) Fruit Graphic Letter | 2002-11-13 | EPA 705-G-2020-2615 | FIFRA, Antimicrobial | This letter addressed to CSPA provides Guidance regarding the use of graphics depicting fruit on antimicrobial labels. | 27 |
| SC Johnson Biofilms Letter | 2004-07-21 | EPA 705-G-2020-2616 | FIFRA, Antimicrobial | This letter provides guidance on biofilm claims for products intended for use in the residential settings. | 101 |
| Shock Letter for swimming pools, hot tubs, and spa products | 2007-06-21 | EPA 705-G-2020-2617 | FIFRA, Antimicrobial | This is a letter that explains the term shock | 103 |
| Surface Safety Claims Guidance | 2016-03-24 | EPA 705-G-2020-2618 | FIFRA; Pesticides; Antimicrobial; | This is a guidance document on surface safety claims | 107 |
| Confirmatory Virucidal Effectiveness Test for Feline Calicivirus (FCV) | 2017-12-27 | EPA 705-G-2020-2620 | FIFRA, Antimicrobial | This document describes how to achieve efficacy of pre-saturated or impregnated towelettes for hard, non-porous surface disinfection against feline calicivirus (FCV), surrogate for norovirus. | 24 |
| Pre-Saturated or Impregnated Confirmatory Virucidal Effective Test against Norovirus | 2017-12-27 | EPA 705-G-2020-2622 | FIFRA, Antimicrobial | This document describes how to achieve virucidal effectiveness for a product used to disinfect hard, non-porous surfaces contaminated with Norovirus | 80 |
| Antimicrobial Science Policies: Disinfectant technical Science Section (DIS/TSS) | 2006-05-02 | EPA 705-G-2020-2625 | FIFRA, Antimicrobial | These documents provide a historical summary of current efficacy related requirements and/or policy for antimicrobial pesticide products, claims, and use patterns. | 15 |
| Acute Toxicity Templates for Antimicrobial Products | 2017-04-25 | EPA 705-G-2020-2626 | FIFRA, Pesticides, Antimicrobial | These templates are designed to guide registrants in required acute toxicity studies. | 7 |
| Determining If A Cleaning Product Is a Pesticide Under FIFRA | 2019-07-03 | EPA 705-G-2020-2628 | FIFRA, Antimicrobial | This fact sheet describes the Agency's longstanding interpretation of the statutory and regulatory language applicable to products marketed as cleaning products that claim, state or imply (by labeling or other means) that they mitigate a pest. | 31 |
| Test Method for the Continuous Reduction of Bacterial Contamination on Copper Alloy Surfaces | 2016-01-29 | EPA 705-G-2020-2629 | FIFRA, Antimicrobial | This document explains the test method for continuous reduction of bacterial contamination | 110 |
| Subdivision G | 1982-11-01 | EPA 705-G-2020-2631 | FIFRA, Antimicrobial | This subdivision of the pesticide registration guidelines concerns the effectiveness of pesticide products. These are efficacy of product guidelines. Primarily HED | 106 |
| Revisions to the Performance Standard for AOAC Use Dilution Methods for Staphylococcus aureus and Pseudomonas aeruginosa | 2013-11-26 | EPA 705-G-2020-2632 | FIFRA, Antimicrobial | Revisions to AOAC UDM to communication changes to performance standards for P. aeruginosa and S. aureus. | 100 |
| Guidance on Warranty Statements | 2006-10-17 | EPA 705-G-2020-2633 | FIFRA, Antimicrobial | This document contains information regarding acceptable warranty and disclaimer statements. | 59 |
| Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims | 2012-12-12 | EPA 705-G-2020-2636 | FIFRA, Antimicrobial | This document represents the Agency's guidance on product performance data and labeling for "mold-related" pesticide products. | 46 |
| Antimicrobial Testing Program | 2018-12-10 | EPA 705-G-2020-2637 | FIFRA, ATP, antimicrobial | Details of ATP including status table. | 17 |
| Consumer Products Treated with Pesticides | 2018-05-29 | EPA 705-G-2020-2638 | FIFRA, Antimicrobial | This explains the treated article exemption | 26 |
| Possible Product Chemistry Triggers for Confirmatory Efficacy Data | 2017-02-21 | EPA 705-G-2020-2641 | FIFRA, Antimicrobial | Chemical Modifications that may trigger additional data requirements | 79 |
| Pesticide Assessment Guidelines Subdivision F Hazard Evaluation: Human and Domestic Animals | 1984-11-01 | EPA 705-G-2020-3389 | FIFRA; pesticides; antimicrobials | This document explains the hazard evaluation process for humans and domestic animals | 76 |
| Product Registration Batching Guidance for Quaternary Ammonium Compounds (Cases 03503 and 3003)--Acute Mammalian Toxicity Data Requirements | 1988-02-26 | EPA 705-G-2020-3390 | acute, toxicity, DCI, quats | This document identifies batches or groups of certain products which may rely on the same acute toxicity data to support product reregistration Data Call-In (DCI) requirements for quats. | 90 |
| Guidance for Waiving Acute Dermal Toxicity Tests for Pesticide Formulations & Supporting Retrospective Analysis | 2016-11-09 | EPA 705-G-2020-3391 | acute, dermal, toxicity, | This document details the procedure for waiving acute dermal toxicity tests. | 55 |
| Conduct of Acute Toxicity Studies | 1997-09-01 | EPA 705-G-2020-3392 | FIFRA; pesticides; antimicrobial | This document details the procedure for conducting acute toxicity studies. | 23 |
| Clarification of Net Contents Declarations for Antimicrobial Wipe Products | 2009-02-04 | EPA 705-G-2020-3507 | FIFRA; Pesticides; Antimicrobial; | This document describes the net contents for wipe products, the website is archived. | 22 |
| CSPA Germs Letter | 2005-01-05 | EPA 705-G-2020-3508 | FIFRA; Pesticides; Antimicrobial; | This letter (addressed to the Consumer Specialty Products Association - CSPA) provides guidance on the use of the term "germs" on antimicrobial labeling. Superseded by 1302 | 29 |
| Antimicrobial Pesticides | 2016-11-15 | EPA 705-G-2020-3509 | FIFRA; Pesticides; Antimicrobial; | Website detailing guidance documents for registration | 12 |
| Certification Statement for Design for the Environment Logo for Pesticide Products | 2007-03-01 | EPA 705-G-2020-3511 | FIFRA; Pesticides; Antimicrobial; | This document explains the certification process for designed for the environment products | 21 |
| Design for the Environment Logo for Antimicrobial Pesticide Products | 2019-05-21 | EPA 705-G-2020-3513 | FIFRA; Pesticides; Antimicrobial; | This document explains designed for the environment on antimicrobial products. | 30 |
| Guidance for the Efficacy Evaluation of Products with Sporicidal Claims Against | 2014-06-01 | EPA 705-G-2020-3515 | FIFRA; Pesticides; Antimicrobial; | This product reviews the evaluations for sporicidal claims. | 52 |
| Guidelines for Dental Issues | 1999-03-31 | EPA 705-G-2020-3516 | FIFRA; Pesticides; Antimicrobial; | This document describes examples of recent inquiries of antimicrobial dental uses, the website is archived. | 63 |
| NSF Logo Letter | 2004-07-01 | EPA 705-G-2020-3533 | FIFRA; Pesticides; Antimicrobial; | Letter describing the NSF logo that can be used on pesticide labels. Remove | 75 |
| Pesticide Label Statements: Pilot Program to Help Promote Environmental Stability | 2017-05-04 | EPA 705-G-2020-3534 | FIFRA; Pesticides; Antimicrobial; | This document explains a pilot program to promote environmental stability | 77 |
| Questions about the DfE Logo for Antimicrobial Pesticide Products | 2019-05-21 | EPA 705-G-2020-3535 | FIFRA; Pesticides; Antimicrobial; | This document gives answers to common questions on DfE | 94 |
| Reregistration and Other Review Programs Predating Pesticide Registration Review | 2017-05-24 | EPA 705-G-2020-3537 | FIFRA; Pesticides; Antimicrobial; | This document gives information on reregistration | 95 |
| Timber Treatment Technologies TimberSil Products | 2008-05-14 | EPA 705-G-2020-3539 | FIFRA; Pesticides; Antimicrobial; | This letter is in response to a request for a barrier determination for TimberSil wood products the website is archived. | 111 |
| Wood Preservative Organic Memorandum Letter | 2007-07-02 | EPA 705-G-2020-3541 | FIFRA; Pesticides; Antimicrobial; | Memo explaining the use of the term organic with respect to pesticide products the website is archived | 117 |
| Frequent Questions for the 2018 Series 810 – Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines | 2019-08-28 | EPA 705-G-2020-3559 | FIFRA, antimicrobial | An FAQ for the 810 guidelines | 44 |
| Antimicrobial Performance Evaluation Program (APEP) | 2019-11-21 | EPA 705-G-2020-3561 | FIFRA, Antimicrobial | This document explains the APEP program, it supersedes the ATP guidance | 10 |
| Standard Evaluation Procedure (SEP) for Chemistry and Acute Toxicity Science Advisory Council (CATSAC) | 2019-11-27 | EPA 705-G-2020-3693 | Pesticide Registration, FIFRA, Acute Toxicity | The SEP generally describes the evaluation process for the determination of pesticide products claiming to be identical or substantially similar for the purposes of relying upon previously submitted product chemistry and/or acute toxicity data, or for bridging acute toxicity data. | 104 |
| Revised Temporary Amendment to Pesticide Registration (PR) Notice 98-10 - Notice to Manufacturers, Producers, Formulators and Registrants of Pesticides Products | 2020-05-11 | EPA 705-G-2020-3701 | FIFRA, pesticides, disinfectants | The temporary amendment to PRN 98-10, signed May 11, 2020, allows registrants to notify EPA of certain formulation and manufacturing facility changes and immediately release the product for sale without waiting for EPA approval. EPA has taken this action in order to address reports of shortages of active ingredients used in surface disinfectants on EPA’s List N: Disinfectants for Use Against SARS-CoV-2, the virus that causes COVID-19, and to address shortages of food-contact surface sanitizer products used on equipment for food manufacturing and food preparation. | 99 |
| Expedited Review of Emerging Viral Pathogens Claim Submissions | 2020-03-09 | EPA 705-G-2020-3702 | FIFRA, pesticides, disinfectants | EPA is expediting the review of emerging viral pathogen claims for EPA registered disinfectants that do not require review of new efficacy data. EPA is currently making every effort to expedite the review and make a regulatory decision for the submissions discussed in this document by at least one to two months faster than the normal PRIA timeframe, depending on the submission. | 41 |
| Standardized Efficacy Study Report and Efficacy Study Summary | 2017-05-24 | EPA 705-G-2020-3704 | FIFRA, Pesticides, Antimicrobial | The study report form contains all of the required elements of a study report as found in 40 CFR part 160, and meets the requirements of PR Notice 2011-3. The Efficacy Study Summary provides a form to create a summary of the important information and variables that are presented in detail in the final report. The summary may be inserted into the study report form. | 105 |
| Test Method for Efficacy of Antimicrobial Agents to Reduce Foodborne Pathogenic Bacteria in Processing Waters for Fruit and Vegetables | 2008-06-01 | EPA 705-G-2020-3707 | FIFRA, pesticides | This test method is used to determine If antimicrobial agents effectively reduce populations of foodborne pathogenic bacteria in fruit and vegetable processing waters. | 109 |
| Electrostatic Spray Applications / List N | 2020-07-07 | EPA 705-G-2020-3709 | FIFRA, Antimicrobials | This guidance outlines an expedited review process for adding directions for use for application using electrostatic spray for products intended for use against SARS-CoV-2, the cause of COVID-19 | 37 |
| Guidance for Waiving Acute Dermal Toxicity Tests for Pesticide Technical Chemicals & Supporting Retrospective Analysis | 2020-12-31 | EPA 705-G-2020-3722 | FIFRA, pesticides, data requirements | This guidance document follows upon the final dermal waiver guidance published in November 2016 for pesticide formulations. This document expands the potential for data waivers for acute dermal studies to single active ingredient technical chemicals (technical chemicals) used to formulate end user products. | 56 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2300, Sanitizers for Use on Hard Surfaces--Efficacy Data Recommendations | 2012-09-04 | EPA 712-C-07-091 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 84 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2700, Products with Prion-Related Claims | 2012-12-01 | EPA 712-C-13-001 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 88 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2000, General Considerations for Testing Public Health Antimicrobial Pesticides | 2018-02-01 | EPA 712-C-17-002 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 81 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2100, Sterilants, Sporicides, and Decontaminants | 2018-02-01 | EPA 712-C-17-003 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 82 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2200, Disinfectants for Use on Environmental Surfaces | 2018-02-01 | EPA 712-C-17-004 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 83 |
| Product Performance Test Guidelines: General, 810.1000, Overview, Definitions, and General Considerations | 1998-03-01 | EPA 712–C–98–001 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 89 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2400, Disinfectants and Sanitizers for Use on Fabrics and Textiles | 2012-12-21 | EPA 730-C-11-003 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 85 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2500, Air Sanitizers | 2012-12-21 | EPA 730-C-11-003 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 86 |
| Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2600, Disinfectants for Use in Water | 2012-12-21 | EPA 730-C-11-003 | FIFRA, Antimicrobial | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 87 |
| The Role of Use-Related Information in Pesticide Risk Assessment and Risk Management | 2000-10-11 | EPA 705-G-2020-0041 | FIFRA | Provides an overview of the role of pesticide use-related information in the regulatory process for risk assessment and risk management for pesticides. | 129 |
| Use Dilution Method Performance Standard Revision Document | 2013-11-26 | EPA 705-G-2020-2518 | Pesticide Analytical Methods | The performance standard for the UDM was reassessed in 2013; the document provides the statistical analysis and data supporting the change. | 130 |
| Sporicidal Claims Against Clostridium difficile | 2018-02-01 | EPA 705-G-2020-2519 | FIFRA | The document provides criteria and references to test methods for developing efficacy data for antimicrobials against C. difficile. | 127 |
| Interim Guidance for the Efficacy Evaluation of Products for Claims Against Candida auris | 2017-01-01 | EPA 705-G-2020-2520 | Pesticide Analytical Methods | The document provides criteria and references to test methods for developing efficacy data for antimicrobials against C. auris. | 118 |
| Methods and Guidance for the Efficacy Evaluation of Antimicrobial Products Against Biofilms on Hard, Non-porous Surfaces | 2017-01-01 | EPA 705-G-2020-2521 | Pesticide Analytical Methods | The document provides criteria and references to test methods for developing efficacy data for antimicrobials against biofilm bacteria. | 125 |
| National Pesticide Standard Repository | 2017-02-06 | EPA 705-G-2020-3077 | Pesticides | Information on how to obtain analytical standards from the EPA National Pesticide Standard Repository, which distributes analytical standards to federal, state and tribal laboratories involved in performing environmental, food, or product monitoring for the enforcement of United States federal and state pesticide laws such as the Federal Food, Drug, and Cosmetic Act and the Federal Insecticide, Fungicide, and Rodenticide Act. | 126 |
| MB-19; Preparing a Pseudomonas aeruginosa or Staphylococcus aureus Biofilm using the CDC Biofilm Reactor | 2019-11-25 | EPA 705-G-2020-3094 | Antimicrobial Testing Methods | Provides the laboratory procedure for growing a biofilm for efficacy testing of disinfectants. | 119 |
| MB-20; Single Tube Method for Determining the Efficacy of Disinfectants Against Bacterial Biofilm | 2019-12-02 | EPA 705-G-2020-3097 | Antimicrobial Testing Methods | Provides a laboratory method for measuring the efficacy of disinfectants against bacterial biofilms. | 120 |
| MB-28; Procedure for the Production and Storage of Spores of Clostridium difficile for Use in the Efficacy Evaluation of Antimicrobial Agents | 2017-12-08 | EPA 705-G-2020-3105 | Antimicrobial Testing Methods | Provides a laboratory method for producing spores of Clostridium difficile. | 121 |
| MB-31; Quantitative Method for Testing Antimicrobial Products Against Spores of Clostridium difficile on Inanimate, Hard, Non-porous Surfaces | 2019-12-21 | EPA 705-G-2020-3107 | Antimicrobial Testing Methods | Provides a laboratory test method for evaluating antimicrobials for claims against clostridium difficile. | 122 |
| MB-35; OECD Quantitative Method for Evaluating the Efficacy of Liquid Antimicrobials Against Candida auris on Hard, Non-porous Surfaces | 2018-01-09 | EPA 705-G-2020-3108 | Antimicrobial Testing Methods | Provides a laboratory test method for testing disinfectants for efficacy against Candida auris. | 123 |
| MB-37; Neutralization Confirmation for Evaluating the Efficacy of Liquid Antimicrobials against Candida auris using the OECD Quantitative Method on Hard, Non-porous Surfaces | 2018-01-09 | EPA 705-G-2020-3109 | Antimicrobial Testing Methods | Provides a laboratory test method for determining the effectiveness of neutralizers in the Candida auris test method. | 124 |
| Suggestions for Applicants on Information Considered when Evaluating Benefits of New Conventional Active Ingredients/Significant New Use Site Requests | 2018-09-01 | EPA 705-G-2020-3140 | Antimicrobial Testing Methods | This memo describes the types of benefits related information that would be useful for registrants to submit in support of their applications to register new conventional active ingredients or for significant new use requests. | 128 |
| Biopesticide Registration | 2017-04-12 | EPA 705-G-2020-0415 | Pesticide Registration; Biopesticides; Pre-Submission Meetings; Regulatory and Data Requirements; Guidance Documents; Work Plans | Resources for an individual or company wanting to register a biopesticide product to include biochemical pesticides, microbial pesticides, or plant-incorporated protectants. | 139 |
| Biopesticides Confidential Statement of Formula | 2010-01-05 | EPA 705-G-2020-0466 | Pesticide Registration; Confidential Statement of Formula; Form 8570-4; Microbial Pesticides; Biochemical Pesticides | This document describes how to prepare a confidential statement of formula (CSF) for biochemical and microbial pesticides. | 140 |
| Pesticide Registration Manual: Chapter 3 - Additional Considerations for Biopesticide Products | 2017-05-23 | EPA 705-G-2020-0500 | Pesticide Registration; Biopesticides; Biochemical Pesticides; Microbial Pesticides; Plant-Incorporated Protectants; Data Requirements; PRIA Review Phases; Genetically Modified Microbial Pesticides; Biotech Notifications | Biopesticides are certain types of pesticides derived from such natural materials as animals, plants, bacteria, and certain minerals that fall into three major classes: microbial pesticides, plant-incorporated protectants, and biochemical pesticides. A separate chapter on biopesticides is included in this manual because there are different requirements for biopesticides that need to be explained in detail. This chapter should be referred to in conjunction with Chapter 2, “Registering a Pesticide Product.” | 214 |
| OECD Data Evaluation Record Templates | 2011-11-18 | EPA 705-G-2020-0516 | Pesticide Registration; Joint Review; Canadian Pest Management Regulatory Agency; Data Templates; Microbial Pesticides | See information about OECD templates used for writing data evaluation record for submitting studies for pesticide registrations. | 211 |
| How to Use OECD Data Evaluation Record Templates | 2011-11-18 | EPA 705-G-2020-0517 | Pesticide Registration; Joint Review; Canadian Pest Management Regulatory Agency; Data Templates; Microbial Pesticides | This document describes the process of development of the OECD data evaluation record templates and provides examples of how to use them. | 153 |
| Minimum Risk Pesticides | 2019-04-30 | EPA 705-G-2020-0557 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Composition; Label; Conditions; Enforcement | The website provides information on the criteria that must be met for a product to qualify for the FIFRA exemption. | 206 |
| Conditions for Minimum Risk Pesticides | 2018-03-14 | EPA 705-G-2020-1090 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Composition; Label | To qualify as minimum risk, a pesticide product must meet six conditions that relate to the ingredients in the product and claims that are made about the product on the label. Learn about these conditions. | 145 |
| State Regulation of Minimum Risk Pesticides | 2016-11-01 | EPA 705-G-2020-1091 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); State Regulation | The states are not required to permit the sale of an exempted product simply because it is exempted under federal pesticide law. | 218 |
| Need for Tolerances and Tolerance Exemptions for Minimum Risk Pesticides | 2018-05-09 | EPA 705-G-2020-1092 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Tolerances; Tolerance Exemptions; FFDCA | The ingredients used in minimum risk products used on food, food crops, food contact surfaces, or animal feed commodities generally have a tolerance or tolerance exemption. Learn about tolerances and tolerance exemptions for minimum risk ingredients. | 210 |
| Enforcement Related to Minimum Risk Pesticides | 2016-11-01 | EPA 705-G-2020-1093 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Federal Enforcement; State Enforcement | If a product does not meet all the requirements of the minimum risk exemption, it must be registered unless eligible for some other exemption. Learn about enforcement actions EPA can take where unregistered products make pesticidal claims. | 150 |
| Personal Insect Repellents and Minimum Risk Pesticides | 2019-07-23 | EPA 705-G-2020-1094 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Insect Repellents; Sunscreen Components; FDA; Public Health Pests | An exempt pesticide product may not bear claims to control rodent, insect or microbial pests in a way that links the pests with specific disease. We are considering a proposal to remove personal mosquito and tick repellents from the minimum risk exemption. | 213 |
| Consumer Specialty Products Association Letter and EPA Response re: Minimum Risk Pesticide Exemption Petition | 2017-03-27 | EPA 705-G-2020-1095 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Public Health Pests; Consumer Specialty Products Association Petition | The Consumer Specialty Products Association petitioned EPA to exclude from the minimum risk pesticide exemption pesticides claiming to control “pests of significant public health importance” and require registration. View the petition and EPA's response. | 146 |
| Commonly Consumed Food Commodities | 2019-07-23 | EPA 705-G-2020-1096 | Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Inert Ingredients; Commonly Consumed Food Commodities; Animal Feed Items; Edible Fats and Oils; 40 CFR 180.950 | Commonly consumed foods are those ingested for their nutrient properties. Food commodities can be either raw agricultural commodities or processed commodities, provided that they are the forms that are sold or distributed for human consumption. Learn more about commonly consumed food commodities, as well as other items from 40 CFR 180.950 (e.g., animal feed items and edible fats and oils), and how they relate to minimum risk pesticides. | 144 |
| Determining If Insect Repellent Skin Patch Products Must Be Registered Under FIFRA | 2018-04-02 | EPA 705-G-2020-1257 | Pesticide Registration; Vitamin B; Biochemical Pesticides; Insect Repellent; Skin Patch; Minimum Risk Pesticides; 40 CFR 152.25(f); Enforcement | Certain skin patch products that claim to repel insects are required to be registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), while others are exempt. Learn more about this issue. | 148 |
| How to Apply for the DfE Logo for Biopesticide Products | 2019-05-06 | EPA 705-G-2020-1296 | Pesticide Labels; Design for the Environment; Logo; Biopesticides; Safer Choice | This page lists the criteria a product must meet and provides instructions to apply for the DfE logo on biopesticide product labels. | 152 |
| Labeling of Pesticide Products under the National Organic Program | 2017-05-24 | EPA 705-G-2020-1305 | Pesticide Labels; National Organic Program; Logo | This notice describes how registrants can obtain EPA approval of label language indicating that all ingredients in a pesticide product and all uses of that pesticide meet the criteria defined in the USDA National Organic Program Rule. | 157 |
| Tips for Plant-Incorporated Protectant (PIP) Experimental Use Permit (EUP) Program Submission | 2017-06-06 | EPA 705-G-2020-1410 | Experimental Use Permits; Biotechnology; Plant-Incorporated Protectants; Acreage; Test Protocols; Objectives; Locations; Seed Increase | Includes information to include in the program description and final program report, recommendations for calculating acreage, use of seed produced under PIP EUPs, and consultation with Biopesticides and Pollution Prevention Division. | 221 |
| Biotech Information - Sharing Memorandum of Understanding | 2000-02-02 | EPA 705-G-2020-1412 | Biotechnology; Plant-Incorporated Protectants; Regulatory Oversight; Information Sharing; Memorandum of Understanding; FDA; USDA | EPA, FDA, and the U.S. Department of Agriculture's Animal and Plant Health Inspection Service/Biotechnology Regulatory Services share the regulatory oversight over genetically engineered plants and the foods derived from such plants. | 141 |
| EPA’s National Organic Program Guidance | 2017-05-24 | EPA 705-G-2020-1417 | Pesticide Registration; National Organic Program; Ingredients | The National Organic Program is a USDA program, including concerning the eligibility of inert ingredients for use in the NOP. EPA’s role is to assist USDA by assuring that USDA’s policies are implemented for organic claims by registered pesticide products. | 151 |
| NAFTA Revised Procedures for Joint Review of Microbials and Semiochemicals | 2002-07-17 | EPA 705-G-2020-1418 | Biopesticides; Joint Review; Canadian Pest Management Regulatory Agency; Microbial Pesticides; Arthropod Semiochemicals; Pre-Submission Consultations; Time Frames; Data Requirements | The Canadian Pest Management Regulatory Agency and EPA have established a process for the joint review of pest control products in which the new active ingredient is a microbial or an arthropod semiochemical (including pheromones). | 208 |
| National Strategy for Modernizing the Regulatory System for Biotechnology Products | 2016-09-01 | EPA 705-G-2020-1646 | Biotechnology; Plant-Incorporated Protectants; Genetically Engineered Microbial Pesticides; Biotechnology Working Group; Coordinated Framework; FDA; USDA; Transparency; Predictability; Efficiency; Best Available Science; Strategy | This National Strategy for Modernizing the Regulatory System for Biotechnology Products sets forth a vision for ensuring that the federal regulatory system is prepared to efficiently assess the risks, if any, of the future products of biotechnology. | 209 |
| Memorandum on Modernizing the Regulatory System for Biotechnology Products | 2015-07-02 | EPA 705-G-2020-1647 | Biotechnology; Plant-Incorporated Protectants; Genetically Engineered Microbial Pesticides; Biotechnology Working Group; Coordinated Framework; FDA; USDA; Transparency; Predictability; Efficiency; Best Available Science; Strategy | This July 2, 2015 memorandum initiated a process to modernize the federal regulatory system for the products of biotechnology and to establish mechanisms for periodic updates of that system. | 158 |
| Plant-Incorporated Protectants Data Symposium | 2016-10-19 | EPA 705-G-2020-2545 | Pesticide Registration; Data; Biotechnology; Plant-Incorporated Protectants; Human Health Risk Assessment; Environmental Risk Assessment; Insect Resistance Management; Coordinated Framework; FDA; USDA | The symposium provided a forum for PIP developers, the agricultural sector and the general public to receive information firsthand on the scope of the scientific review process that determines the safety of PIPs and on the pesticide registration process as a whole. EPA, FDA and USDA representatives gave an overview of the regulatory system that applies to biotechnology in the United States in the context of the Coordinated Framework for Regulation of Biotechnology. | 215 |
| Overview of Plant Incorporated Protectants | 2019-05-20 | EPA 705-G-2020-2546 | Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Data; Regulation History; Scientific Advisory Panels; Risk Assessment | Plant-incorporated protectants are pesticidal substances produced by plants and the genetic material necessary for the plant to produce the substance. For example, scientists can take the gene for a specific Bt pesticidal protein and introduce the gene into the plant's genetic material. Then the plant manufactures the pesticidal protein that controls the pest when it feeds on the plant. Both the protein and its genetic material are regulated by EPA; the plant itself is not regulated. | 212 |
| Insect Resistance Management for Bt Plant-Incorporated Protectants | 2017-08-22 | EPA 705-G-2020-2547 | Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Insect Resistance Management; Pyramids; Stacks; Refuge; Mitigation Strategies; Compliance Assurance Plans; Resistance Monitoring; Scientific Advisory Panels | EPA places a high value on the efficacy of Bt PIPs and on preserving their significant agricultural and environmental benefits. Therefore, the Agency is committed to maintaining effective oversight of these products to mitigate the development of resistance in the target pests. To counter the threat of resistance, EPA has mandated the implementation of an Insect Resistance Management (IRM) plan for each commercially registered Bt PIP. The goal of IRM is to delay the onset of resistance for as long as possible, though it is important to note that it may not be possible to entirely prevent resistance from evolving. | 155 |
| Tier-Based Testing for the Effects of Proteinaceous Insecticidal Plant-Incorporated Protectants | 2007-04-06 | EPA 705-G-2020-2548 | Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Nontarget Invertebrates; Environmental Risk Assessment; Data | The purpose of this paper is to summarize scientific and regulatory information on nontarget invertebrate testing and evaluation of new products expressing insecticidal proteins in an ecological risk assessment. The information included provides a general discussion for conducting non-target invertebrate ecological risk assessments for crops expressing insecticidal proteins. | 219 |
| Tips for Avoiding Confidential Statement of Formula or Product Chemistry Issues with Biopesticides | 2019-08-02 | EPA 705-G-2020-2549 | Pesticide Registration; Confidential Statement of Formula; Form 8570-4; Microbial Pesticides; Biochemical Pesticides; Product Chemistry; Biochemical Classification Committee; Plant-Incorporated Protectants; Pre-Registration Meeting | These recommendations may assist registrants in avoiding common mistakes when preparing and submitting biopesticide product chemistry data and the Confidential Statement of Formula (CSF). | 220 |
| Clarification of the Information Necessary to Determine the Formation of Unintended Ingredients in Microbial Pesticide Products | 2019-05-06 | EPA 705-G-2020-2550 | Unintentional Ingredients; Manufacturing Process; Microbial Pesticides; Critical Control Points; Quality Assurance; Quality Control; Contamination; Contaminants | Data and information needed to satisfy the OCSPP Guidelines 885.1200 (manufacturing process) and 885.1300 (formation of unintentional ingredients) for new microbial active ingredients must be accompanied by a full description of the production process, ingredients used, and quality assurance (QA) and quality control (QC) measures. The intent of this document is to provide additional clarification to applicants of novel microbial pesticides and facilitate the development of complete submission packages. | 143 |
| Draft Guidance for Plant Regulator Label Claims, Including Plant Biostimulants | 2019-03-25 | EPA 705-G-2020-2558 | Plant Regulators; Claims; Plant Biostimulants; Plant Nutrients; Plant Inoculants; Soil Amendments; Vitamin-Hormone Products; Exclusions | In recognition of the growing categories of products generally known as plant biostimulants, this document is intended to provide guidance on identifying product label claims that are considered to be plant regulator claims by the Agency, thereby subjecting the products to regulation as pesticides under FIFRA. | 149 |
| Sample Request for Additional Information to Support a FIFRA Determination Request | 2020-01-27 | EPA 705-G-2020-2559 | Microbial Products; Pesticide Determination | Information sent to stakeholders, who ask EPA to make determinations as to whether their microbial products are pesticides. As these types of requests need to now be submitted under PRIA (as an M009), EPA does its best to provide guidance as to what needs to be submitted for a successful application: (1) complete composition of the product, (2) label and advertising associated with the product, (3) information that shows the microorganism(s) in the product has/have non-pesticidal activity, and (4) confirmation as to whether the microorganism(s) in the product is/are intergeneric or naturally occurring. | 217 |
| EPA's Regulation of Biotechnology for Use in Pest Management | 2019-12-23 | EPA 705-G-2020-2647 | Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Genetically Modified Microbial Pesticides; Herbicide-Tolerant Crops; Risk Assessment; Gene Flow; Insect Resistance Management; USDA; FDA; Tolerance Exemptions; Data Requirements; FIFRA | To address the challenges of biotechnology, the Environmental Protection Agency (EPA), the U.S. Department of Agriculture (USDA), and the Food and Drug Administration (FDA) have shared responsibility for regulating agricultural biotechnology in the United States. In particular, EPA regulates pesticides created through biotechnology as a part of its regulatory jurisdiction over all pesticides marketed and used in the United States. As such, EPA has tailored its basic regulatory framework to fit the distinctive characteristics of these genetically engineered biological pesticides. A description of this framework is provided below. | 1009 |
| Introduction to Biotechnology Regulation for Pesticides | 2017-06-06 | EPA 705-G-2020-2653 | Pesticide Registration; Data; Biotechnology; Plant-Incorporated Protectants; Genetically Engineered Microbial Pesticides; Herbicide-Tolerant Plants; Gene Flow; Risk Assessments; Insect Resistance Management | This document provides an overview of what biotechnology pesticide products are and how EPA evaluates them during the registration process. | 156 |
| Inert Ingredients Eligible for FIFRA 25(b) Pesticide Products | 2016-11-16 | EPA 705-G-2020-3380 | Minimum Risk Pesticide; 40 CFR 152.25(f); Inert Ingredient; Composition; Tolerance Exemption Status | This list includes the inert ingredients that can be used in minimum risk pesticide products. | 154 |
| Design for the Environment Logo for Biopesticide Products | 2019-05-21 | EPA 705-G-2020-3381 | Pesticide Registration; Design for the Environment; Logo; Biopesticides | Brief description of how to obtain the Design for the Environment (DoE) logo, what the DoE logo means on biopesticide product labels, and when the DoE logo can be used. | 147 |
| Minimum Risk - Addition of an Inert Ingredient or Active Ingredient to the Exemption | 2017-06-16 | EPA 705-G-2020-3382 | Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption; Adding Active or Inert Ingredients; Petition | This information describes that EPA is looking to set up a streamlined process for adding ingredients to the minimum risk pesticide active or inert lists and how parties interested in adding a substance to the two lists can proceed in the meantime. | 204 |
| Minimum Risk Pesticide: Definition and Product Confirmation | 2018-04-02 | EPA 705-G-2020-3383 | Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption | Description of what a minimum risk pesticide is and a statement as to whether EPA will confirm minimum risk pesticide status. | 205 |
| Active Ingredients Allowed in Minimum Risk Pesticide Products | 2017-05-24 | EPA 705-G-2020-3384 | Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption; Active Ingredient; Composition; FFDCA; Tolerance Exemption Status | The following active ingredients can be used in pesticide products that are exempt from the requirements of the Federal Insecticide, Fungicide, and Rodenticide Act under the minimum risk exemption regulations in 40 CFR 152.25(f). They can be used alone or in combination with other substances listed in this paragraph, provided that all of the criteria for minimum risk exemption are met. | 131 |
| Minimum Risk Pesticides - Inert Ingredient and Active Ingredient Eligibility under 40 CFR 152.25(f) | 2018-03-19 | EPA 705-G-2020-3385 | Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption; Active Ingredient; Inert Ingredient; Eligibility; Composition | Ingredients that are included on both the Minimum Risk Active Ingredient list and the Minimum Risk Inert Ingredients list may be used either as an active ingredient or an inert ingredient. However, the active ingredient and inert ingredient lists are not interchangeable. Unless the ingredient appears on both lists, it can only be used based on the list it appears on. | 207 |
| Risk Assessment and Weight-of-the Evidence (WOE): Outcome from Meeting Between the Biopesticide Industry Alliance (BPIA) and EPA’s Office of Pesticide Programs (OPP) | 2020-02-13 | EPA 705-G-2020-3386 | Risk Assessment; Weight-of-the-Evidence; Data; Rationale; I-DEEM; Tolerance; Tolerance Exemption; Nonfood Determination; FFDCA | Outcome from meeting between BPIA and OPP to discuss what data are needed for a risk assessment, what BioDEEM is and when is it triggered, possibility of demonstrating an adequate margin of safety between actual exposure and an effect level, possible regulatory tools to implement a determination of safety, and how much data to present to EPA before an application is submitted. | 216 |
| Information Needed to Support a Biochemical Classification Determination | 2020-01-16 | EPA 705-G-2020-3387 | Biochemical Pesticide; Biochemical Classification Committee; Criteria; Naturally Occurring Compound; Structurally Similar and Functionally Identical to Naturally Occurring Compound; Non-Toxic Mode of Action; History of Safe Exposure; Other Supporting Info | Describes the information a prospective pesticide applicant needs to provide to EPA to allow it to make a determination whether a particular substance is a biochemical pesticide. | 1010 |
| BPPD’s Risk Assessment Elements “Cheat Sheet” for Applicants | 2019-09-01 | EPA 705-G-2020-3388 | Risk Assessment; Product Uses; Use Rates; Toxic Effects; Open Scientific Literature Information; Qualitative; Quantitative; Aggregate | When submitting a pesticide product registration application to EPA/OPP/BPPD, it is essential that you (applicant) address all applicable data requirements per the Code of Federal Regulations (CFR), part 158. However, it is also imperative that you (applicant) characterize your use sites, use patterns, rates and generally summarize your toxicity data so that a comprehensive risk assessment, taking into account all aspects of your product, can be performed by EPA. Often, when one or more of these pieces of information is missing from an application, the applicant is unsatisfied with the unavoidably conservative assessment that is performed. Further, presenting this information to EPA upfront can alleviate some unnecessary back-and-forth exchanges between EPA and the applicant and subsequent review time lost. EPA/BPPD highly recommends that applicants answer the following questions in writing in either a cover letter, data volume, or both when submitting their new product application. | 142 |
| Microbial Pesticide Test Guidelines: OCSPP 885.1250: Deposition of a Sample in a Nationally Recognized Culture Collection | 2012-04-01 | EPA 712-C-12-027 | Test Guideline; Microbial Pesticide; Culture Collection Deposition; 885.1250 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 159 |
| Microbial Pesticide Test Guidelines: OPPTS 885.5000 Background for Microbial Pesticides Testing | 1996-02-01 | EPA 712-C-96-056 | Test Guideline; Microbial Pesticide; Environmental Expression Testing Background; Tier II Testing; 885.5000 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 200 |
| Biochemicals Test Guidelines: OPPTS 880.1100 Product Identity and Composition | 1996-02-01 | EPA 712-C-96-273 | Test Guideline; Biochemical Pesticide; Product Identity; Composition; 880.1000 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 132 |
| Microbial Pesticide Test Guidelines: OPPTS 885.1100 Product Identity | 1996-02-01 | EPA 712-C-96-273 | Test Guideline; Microbial Pesticide; Product Identity; 885.1100 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 161 |
| Biochemicals Test Guidelines: OPPTS 880.1200 Description of Starting Materials, Production, and Formulation Process | 1996-02-01 | EPA 712-C-96-274 | Test Guideline; Biochemical Pesticide; Starting Materials; Production; Formulation Process; 880.1200 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 133 |
| Biochemicals Test Guidelines: OPPTS 880.1400 Discussion of Formation of Impurities | 1996-02-01 | EPA 712-C-96-275 | Test Guideline; Biochemical Pesticide; Impurities; 880.1400 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 134 |
| Biochemicals Test Guidelines: OPPTS 880.3550 Immunotoxicity | 1996-02-01 | EPA 712-C-96-280 | Test Guideline; Biochemical Pesticide; Immunotoxicity; 880.3550 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 135 |
| Microbial Pesticide Test Guidelines: OPPTS 885.0001 Overview for Microbial Pest Control Agents | 1996-02-01 | EPA 712-C-96-280 | Test Guideline; Microbial Pesticide; Microbial Pesticide Testing Overview; 885.0001 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 160 |
| Biochemicals Test Guidelines: OPPTS 880.3800 Immune Response | 1996-02-01 | EPA 712-C-96-281 | Test Guideline; Biochemical Pesticide; Immune Response; 880.3800 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 136 |
| Biochemicals Test Guidelines: OPPTS 880.4350 Nontarget Insect Testing | 1996-02-01 | EPA 712-C-96-285 | Test Guideline; Biochemical Pesticide; Nontarget Insect Testing; 880.4350 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 137 |
| Biochemicals Test Guidelines: OPPTS 880.4425 Dispenser Water Leaching | 1996-02-01 | EPA 712-C-96-286 | Test Guideline; Biochemical Pesticide; Dispenser Water Leaching; 880.4425 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 138 |
| Microbial Pesticide Test Guidelines: OPPTS 885.1200 Manufacturing Process | 1996-02-01 | EPA 712-C-96-293 | Test Guideline; Microbial Pesticide; Manufacturing Process; 885.1200 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 162 |
| Microbial Pesticide Test Guidelines: OPPTS 885.1300 Discussion of Formation of Unintentional Ingredients | 1996-02-01 | EPA 712-C-96-294 | Test Guideline; Microbial Pesticide; Unintentional Ingredients; 885.1300 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 163 |
| Microbial Pesticide Test Guidelines: OPPTS 885.1400 Analysis of Samples | 1996-02-01 | EPA 712-C-96-295 | Test Guideline; Microbial Pesticide; Analysis of Samples; 885.1400 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 164 |
| Microbial Pesticide Test Guidelines: OPPTS 885.1500 Certification of Limits | 1996-02-01 | EPA 712-C-96-296 | Test Guideline; Microbial Pesticide; Certification of Limits; 885.1500 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 165 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2000 Background for Residue Analysis of Microbial Pest Control Agents | 1996-02-01 | EPA 712-C-96-299 | Test Guideline; Microbial Pesticide; Residue Analysis Background; 885.2000 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 166 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2100 Chemical Identity | 1996-02-01 | EPA 712-C-96-300 | Test Guideline; Microbial Pesticide; Chemical Identity; Residues; 885.2100 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 167 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2200 Nature of the Residue in Plants | 1996-02-01 | EPA 712-C-96-302 | Test Guideline; Microbial Pesticide; Residue Nature in Plants; 885.2200 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 168 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2250 Nature of the Residue in Animals | 1996-02-01 | EPA 712-C-96-303 | Test Guideline; Microbial Pesticide; Residue Nature in Animals; 885.2250 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 169 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2300 Analytical Methods—Plants | 1996-02-01 | EPA 712-C-96-304 | Test Guideline; Microbial Pesticide; Residue; Analytical Methods; Plants; 885.2300 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 170 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2350 Analytical Methods—Animals | 1996-02-01 | EPA 712-C-96-305 | Test Guideline; Microbial Pesticide; Residue; Analytical Methods; Animals; 885.2350 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 171 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2400 Storage Stability | 1996-02-01 | EPA 712-C-96-306 | Test Guideline; Microbial Pesticide; Residue; Storage Stability; 885.2400 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 172 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2500 Magnitude of Residues in Plants | 1996-02-01 | EPA 712-C-96-307 | Test Guideline; Microbial Pesticide; Magnitude of Residues; Plants; 885.2500 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 173 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2550 Magnitude of Residues in Meat, Milk, Poultry, and Eggs | 1996-02-01 | EPA 712-C-96-308 | Test Guideline; Microbial Pesticide; Magnitude of Residues; Meat; Milk; Poultry; Eggs; 885.2550 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 174 |
| Microbial Pesticide Test Guidelines: OPPTS 885.2600 Magnitude of Residues in Potable Water, Fish, and Irrigated Crops | 1996-02-01 | EPA 712-C-96-309 | Test Guideline; Microbial Pesticide; Magnitude of Residues; Potable Water; Fish; Irrigated Crops; 885.2600 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 175 |
| Microbial Pesticide Test Guidelines: OPPTS 885.5400 Expression in a Marine or Estuarine Environment | 1996-02-01 | EPA 712-C-96-312 | Test Guideline; Microbial Pesticide; Marine or Estuarine Environment Expression; Tier II Testing; 885.5400 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 203 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3000 Background-Mammalian Toxicity/Pathogenicity/Infectivity | 1996-02-01 | EPA 712-C-96-314 | Test Guideline; Microbial Pesticide; Background; Toxicity; Pathogenicity; Infectivity; Mammals; 885.3000 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 176 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3050 Acute Oral Toxicity/Pathogenicity | 1996-02-01 | EPA 712-C-96-315 | Test Guideline; Microbial Pesticide; Acute Oral Toxicity and Pathogenicity; Mammals; 885.3050 | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 177 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3100 Acute Dermal Toxicity/Pathology | 1996-02-01 | EPA 712-C-96-316 | Test Guideline; Microbial Pesticide; Acute Dermal Toxicity and Pathology; Mammals; 885.3100 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 178 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3150 Acute Pulmonary Toxicity/Pathogenicity | 1996-02-01 | EPA 712-C-96-317 | Test Guideline; Microbial Pesticide; Acute Pulmonary Toxicity and Pathogenicity; Mammals; 885.3150 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 179 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3200 Acute Injection Toxicity/Pathogenicity | 1996-02-01 | EPA 712-C-96-318 | Test Guideline; Microbial Pesticide; Acute Injection Toxicity and Pathogenicity; Mammals; 885.3200 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 180 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3400 Hypersensitivity Incidents | 1996-02-01 | EPA 712-C-96-320 | Test Guideline; Microbial Pesticide; Hypersensitivity Incidents; 885.3400 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 181 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3500 Cell Culture | 1996-02-01 | EPA 712-C-96-321 | Test Guideline; Microbial Pesticide; Cell Culture; Mammals; 885.3500 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 182 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3550 Acute Toxicology, Tier II | 1996-02-01 | EPA 712-C-96-322 | Test Guideline; Microbial Pesticide; Mammals; Acute Toxicology; Tier II Testing; 885.3550 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 183 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3600 Subchronic Toxicity/Pathogenicity | 1996-02-01 | EPA 712-C-96-323 | Test Guideline; Microbial Pesticide; Mammals; Subchronic Toxicity and Pathogenicity; Tier II Testing; 885.3600 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 184 |
| Microbial Pesticide Test Guidelines: OPPTS 885.3650 Reproductive/Fertility Effects | 1996-02-01 | EPA 712-C-96-324 | Test Guideline; Microbial Pesticide; Mammals; Reproductive and Fertility Effects; Tier III Testing; 885.3650 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 185 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4000 Background for Nontarget Organism Testing of Microbial Pest Control Agents | 1996-02-01 | EPA 712-C-96-328 | Test Guideline; Microbial Pesticide; Nontarget Organism Testing Background; 885.4000 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 186 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4050 Avian Oral, Tier I | 1996-02-01 | EPA 712-C-96-329 | Test Guideline; Microbial Pesticide; Avian Oral Toxicity and Pathogenicity; 885.4050 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 187 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4100 Avian Inhalation Test, Tier I | 1996-02-01 | EPA 712-C-96-330 | Test Guideline; Microbial Pesticide; Avian Inhalation Toxicity and Pathogenicity; 885.4100 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 188 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4150 Wild Mammal Testing, Tier I | 1996-02-01 | EPA 712-C-96-331 | Test Guideline; Microbial Pesticide; Wild Mammal Toxicity and Pathogenicity; 885.4150 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 189 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4200 Freshwater Fish Testing, Tier I | 1996-02-01 | EPA 712-C-96-332 | Test Guideline; Microbial Pesticide; Freshwater Fish Toxicity and Pathogenicity; 885.4200 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 190 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4240 Freshwater Aquatic Invertebrate Testing, Tier I | 1996-02-01 | EPA 712-C-96-333 | Test Guideline; Microbial Pesticide; Freshwater Invertebrate Toxicity and Pathogenicity; 885.4240 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 191 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4280 Estuarine and Marine Animal Testing, Tier I | 1996-02-01 | EPA 712-C-96-334 | Test Guideline; Microbial Pesticide; Estuarine and Marine Animal Toxicity and Pathogenicity; 885.4280 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 192 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4300 Nontarget Plant Studies, Tier I | 1996-02-01 | EPA 712-C-96-335 | Test Guideline; Microbial Pesticide; Nontarget Plant Testing; 885.4300 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 193 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4340 Nontarget Insect Testing, Tier I | 1996-02-01 | EPA 712-C-96-336 | Test Guideline; Microbial Pesticide; Nontarget Insect Toxicity and Pathogenicity; 885.4340 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 194 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4380 Honey Bee Testing, Tier I | 1996-02-01 | EPA 712-C-96-337 | Test Guideline; Microbial Pesticide; Honey Bee Toxicity and Pathogenicity; 885.4380 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 195 |
| Microbial Pesticide Test Guidelines: OPPTS 885.5200 Expression in a Terrestrial Environment | 1996-02-01 | EPA 712-C-96-338 | Test Guideline; Microbial Pesticide; Terrestrial Environment Expression; Tier II Testing; 885.5200 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 201 |
| Microbial Pesticide Test Guidelines: OPPTS 885.5300 Expression in a Freshwater Environment | 1996-02-01 | EPA 712-C-96-339 | Test Guideline; Microbial Pesticide; Freshwater Environment Expression; Tier II Testing; 885.5300 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 202 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4600 Avian Chronic Pathogenicity and Reproduction Test, Tier III | 1996-02-01 | EPA 712-C-96-342 | Test Guideline; Microbial Pesticide; Avian Chronic Pathogenicity and Reproduction; Tier III Testing; 885.4600 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 196 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4650 Aquatic Invertebrate Range Testing, Tier III | 1996-02-01 | EPA 712-C-96-343 | Test Guideline; Microbial Pesticide; Aquatic Invertebrate Range Testing; Tier III Testing; 885.4650 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 197 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4700 Fish Life Cycle Studies, Tier III | 1996-02-01 | EPA 712-C-96-344 | Test Guideline; Microbial Pesticide; Fish Life Cycle Studies; Tier III Testing; 885.4700 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 198 |
| Microbial Pesticide Test Guidelines: OPPTS 885.4750 Aquatic Ecosystem Test | 1996-02-01 | EPA 712-C-96-345 | Test Guideline; Microbial Pesticide; Aquatic Ecosystem Test; Tier III Testing; 885.4750 | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 199 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1350, [Reserved] | 2015-07-01 | EPA 705-G-2020-0162 | Test Guideline; Ecological Effects | Draft guideline. FINAL Guideline has not yet been published. | 260 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1500, [Reserved] | 2015-07-01 | EPA 705-G-2020-0165 | Test Guideline; Ecological Effects | Draft guideline. FINAL Guideline has not yet been published. | 262 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1790, [Reserved] | 2015-07-01 | EPA 705-G-2020-0171 | Test Guideline; Ecological Effects | Draft guideline. FINAL Guideline has not yet been published. | 267 |
| E-Submission Environmental Study Supplemental Files | 2002-06-27 | EPA 705-G-2020-0490 | Pesticide Registration; E-submission; Environmental Study Supplemental; Aquatic Toxicity Study | This document provides standard format for electronic submission of supplemental data files in support of aquatic toxicity studies. | 247 |
| E-submission for avian reproduction studies | 2002-06-01 | EPA 705-G-2020-0495 | Pesticide Registration; E-submission Avian Reproduction Studies | Guidance information about electronic submission for avian reproduction studies. | 248 |
| E-Submission for Terrestrial and Aquatic Plant Studies | 2001-02-01 | EPA 705-G-2020-0496 | Pesticide Registration; E-submission Terrestrial and Aquatic Plant Studies | Guidance information about electronic submissions for terrestrial and aquatic plant studies. | 250 |
| E-submission for surface water and groundwater field studies and monitoring data | 2001-02-01 | EPA 705-G-2020-0497 | Pesticide Registration; E-submission Surface Water Ground Water Monitoring Data | Guidance information about electronic submission for surface water and groundwater field studies and monitoring data. | 249 |
| Draft Test Guideline: Fish Acute Toxicity Mitigated By Humic Acid | 2017-01-01 | EPA 705-G-2020-1330 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 240 |
| Draft Test Guideline: Mysid Chronic Toxicity Test | 2017-01-01 | EPA 705-G-2020-1334 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 243 |
| Draft Test Guideline: Fish Life Cycle Toxicity | 2017-01-01 | EPA 705-G-2020-1335 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 241 |
| Draft Test Guideline: Whole Sediment Acute Toxicity Invertebrates, Marine | 2015-07-01 | EPA 705-G-2020-1336 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 246 |
| Draft Test Guideline: Chironomid Sediment Toxicity Test | 2017-01-01 | EPA 705-G-2020-1337 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 238 |
| Draft Test Guideline: Tadpole/Sediment Subchronic Toxicity Test | 2017-01-01 | EPA 705-G-2020-1338 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 245 |
| Draft Test Guideline: Aquatic Food Chain Transfer | 2017-01-01 | EPA 705-G-2020-1339 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 237 |
| Draft Test Guideline: Generic Freshwater Microcosm Test, Laboratory | 2017-01-01 | EPA 705-G-2020-1340 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 242 |
| Draft Test Guideline: Site-Specific Aquatic Microcosm Test, Laboratory | 2017-01-01 | EPA 705-G-2020-1341 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 244 |
| Draft Test Guideline: Field Testing For Aquatic Organisms | 2017-01-01 | EPA 705-G-2020-1342 | Test Guidelines for Pesticides and Toxic Substances | The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 239 |
| Guidance for Use When Regurgitation is Observed in Avian Acute Toxicity Studies with Passerine Species | 2012-04-09 | EPA 705-G-2020-1379 | Pesticide Science and Assessing Pesticide Risks | Guidance based on comparison of results from the TG223 validation studies to results from avian acute oral studies previously submitted to EPA for two test chemicals following EPA's 850.2100 (public draft) guidelines. | 341 |
| Toxicity Testing and Ecological Risk Assessment Guidance for Benthic Invertebrates | 2014-04-10 | EPA 705-G-2020-1384 | Pesticide Science and Assessing Pesticide Risks | Guidance for when to require whole sediment toxicity tests and how to integrate sediment toxicity tests results into EFED ecological risk assessments. | 355 |
| NAFTA Guidance Document for Conducting Terrestrial Field Dissipation Studies | 2006-03-31 | EPA 705-G-2020-1404 | Pesticide Science and Assessing Pesticide Risks | Harmonized guidance for TFD studies that demonstrate transformation, transport and fate of pesticides under representative actual use conditions. Field studies substantiate physicochemical, mobility and biotransformation data from laboratory studies. | 345 |
| Guidance for Use When Regurgitation is Observed in Avian Acute Toxicity | 2012-01-01 | EPA 705-G-2020-3254 | Acute oral avian toxicity, Test guidelines | Recommends an alternative testing option when regurgitation is observed in passerine studies. | 340 |
| Label Review Manual (Chapter 8_Env Hazards) | 2012-01-01 | EPA 705-G-2020-3262 | Label statements | This guidance provides the language informing users of the potential hazards to the environment from transport, use, storage, or spill of the product and indicates in what circumstances given statements are required. | 343 |
| SOP: Evaluation of Patent Assertion Claims of Greater Than Additive (GTA) Effects | 2020-01-01 | EPA 705-G-2020-3288 | Synergy, Patent claims | Addresses risk estimate uncertainties associated with U.S. patent assertions of greater than additive effects in mixtures of pesticide active ingredients for controlling pests (often referred to as “synergy”). | 353 |
| Adsorption and desorption of test compound in soils or sediments | 2012-05-01 | EPA 705-G-2020-3294 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 231 |
| Laboratory Volatility of [test compound] | 2012-12-01 | EPA 705-G-2020-3295 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 344 |
| Hydrolysis of [test compound] at pH [4,7, and 9, or other values studied] | 2012-05-01 | EPA 705-G-2020-3296 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 342 |
| Aqueous Photolysis of [test compound] | 2012-05-01 | EPA 705-G-2020-3297 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 235 |
| Soil Photolysis of [test compound] | 2012-05-01 | EPA 705-G-2020-3298 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 352 |
| Aerobic (or Anaerobic) Degradation in Soil of [test compound] | 2012-05-01 | EPA 705-G-2020-3299 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 233 |
| Aerobic (or Anaerobic) Degradation in Aquatic Systems | 2012-05-01 | EPA 705-G-2020-3300 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 232 |
| Field Dissipation of [test compound] | 2012-05-01 | EPA 705-G-2020-3301 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 337 |
| Prospective Ground Water Monitoring of [test compound] | 2012-12-01 | EPA 705-G-2020-3302 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 349 |
| Field volatility of [test compound] | 2012-12-01 | EPA 705-G-2020-3303 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 338 |
| Sample storage stability of [test compound(s)] in [frozen soil, water, etc.] | 2012-12-01 | EPA 705-G-2020-3304 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 351 |
| Acute Toxicity Effects of {TAI or EUP} on Earthworms | 2004-05-01 | EPA 705-G-2020-3305 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 225 |
| Acute Toxicity of {TAI or EUP} to Freshwater Invertebrates - [Daphnia sp.] | 2004-05-01 | EPA 705-G-2020-3306 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 229 |
| Acute Toxicity of {TAI or EUP} to Fish - [name of species] | 2004-05-01 | EPA 705-G-2020-3307 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 228 |
| Chronic Toxicity of {TAI or EUP} to Fresh Water Invertebrates - [Daphnia sp.] | 2004-05-01 | EPA 705-G-2020-3308 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 236 |
| Toxicity of {TAI or EUP} to Fish Early Life-Stage | 2004-05-01 | EPA 705-G-2020-3309 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 354 |
| [Fish or Oyster] Bioconcentration Factor (BCF) of [Test Compound] | 2012-12-01 | EPA 705-G-2020-3310 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 222 |
| Acute Oral Toxicity of {TAI or EUP} to Avian Species - [name of species] | 2004-05-01 | EPA 705-G-2020-3311 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 224 |
| Acute Dietary Toxicity of {TAI or EUP} to Avian Species - [name of species] | 2004-05-01 | EPA 705-G-2020-3312 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 223 |
| Reproductive Effects of {TAI or EUP} on Avian Species - [name of species] | 2004-05-01 | EPA 705-G-2020-3313 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 350 |
| Acute Toxicity of {TAI or EUP} to Terrestrial Vascular Plant - [name of species - seed germination-root elongation/seedling emergence/vegetative vigour] | 2004-05-01 | EPA 705-G-2020-3314 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 230 |
| Acute Toxicity of {TAI or EUP} to Aquatic Vascular Plants - [name of species] | 2004-05-01 | EPA 705-G-2020-3315 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 227 |
| Acute Toxicity of {TAI or EUP} to Algae - [name of species] | 2004-05-01 | EPA 705-G-2020-3316 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 226 |
| Analytical method for [analyte(s)] in [soil, water, air, or other environmental medium] | 2012-12-01 | EPA 705-G-2020-3317 | Study Template | The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. | 234 |
| Process for Requiring Exposure and Effects Testing for Assessing Risks to Bees during Registration and Registration Review | 2016-01-01 | EPA 705-G-2020-3627 | Pollinators, Honey Bees | The intent of this document is to provide interim guidance to the public and staff within EPA OPP for determining when honey bee exposure and effects data identified in the EPA’s 2014 risk assessment framework Guidance for Assessing Pesticide Risks to Bees and the 2016 Guidance on Exposure and Effects Testing for Assessing Risks To Bees are required. | 348 |
| Fish Bioconcentration Data Requirement: Guidance for Selection of Number of Treatment Concentration | 2020-07-18 | EPA 705-G-2020-3708 | Pesticide data requirement, Testing Guidance | Clarify EPA recommendations for the number of treatment concentrations needed to result in acceptable fish bioconcentration factor (BCF) studies for pesticide registration (supplements OCSPP Test Guideline 850.1730). | 339 |
| Fate, Transport and Transformation Test Guidelines: Ground Water Monitoring Test Guidelines, 835.7100, Guidance for Prospective Ground-Water Monitoring Studies | 2008-08-01 | EPA 712-B-10-001 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 299 |
| OCSPP 850.4000: Background and Special Considerations- Tests with Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil-Core Microcosms [EPA 712-C-013] | 2012-01-01 | EPA 712-C-013 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 347 |
| OCSPP 850.3000: Background and Special Considerations- Tests with Terrestrial Beneficial Insects, Invertebrates and Microorganisms [EPA 712-C-020] | 2012-01-01 | EPA 712-C-020 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 346 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3140, Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test) [SUPERSEDES 835.3120] | 2008-10-01 | EPA 712-C-08-001 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 309 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3190, Aerobic Mineralization in Surface Water - Simulation Biodegradation Test | 2008-10-01 | EPA 712-C-08-002 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 312 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3215, Inherent Biodegradability - Concawe Test | 2008-10-01 | EPA 712-C-08-003 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 315 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3240, Simulation Test—Aerobic Sewage Treatment: A. Activated Sludge Units | 2008-10-01 | EPA 712-C-08-004 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 317 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3260, Simulation Test—Aerobic Sewage Treatment: B. Biofilms | 2008-10-01 | EPA 712-C-08-005 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 318 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3280, Simulation Tests to Assess the Primary and Ultimate Biodegradability of Chemicals Discharged to Wastewater | 2008-10-01 | EPA 712-C-08-006 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 319 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3420, Anaerobic Biodegradability of Organic Compounds in Digested Sludge: By Measurement of Gas Production | 2008-10-01 | EPA 712-C-08-007 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 322 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1230, Adsorption/Desorption (Batch Equilibrium) | 2008-10-01 | EPA 712-C-08-009 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 326 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1240, Leaching Studies | 2008-10-01 | EPA 712-C-08-010 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 327 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1410, Laboratory Volatility | 2008-10-01 | EPA 712-C-08-011 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 328 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2120, Hydrolysis [SUPERSEDES 835.2110] | 2008-10-01 | EPA 712-C-08-012 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 300 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2240, Photodegradation in Water | 2008-10-01 | EPA 712-C-08-013 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 303 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2370, Photodegradation in Air | 2008-10-01 | EPA 712-C-08-014 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 305 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2410, Photodegradation in Soil | 2008-10-01 | EPA 712-C-08-015 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 306 |
| Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4100, Aerobic Soil Metabolism | 2008-10-01 | EPA 712-C-08-016 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 332 |
| Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4200, Anaerobic Soil Metabolism | 2008-10-01 | EPA 712-C-08-017 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 333 |
| Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4300, Aerobic Aquatic Metabolism | 2008-10-01 | EPA 712-C-08-018 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 334 |
| Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4400, Anaerobic Aquatic Metabolism | 2008-10-01 | EPA 712-C-08-019 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 335 |
| Fate, Transport and Transformation Test Guidelines: Volatility from Soil Test Guidelines, 835.8100, Field Volatility | 2008-10-01 | EPA 712-C-08-024 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 336 |
| Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6100, Terrestrial Field Dissipation | 2008-10-01 | EPA 712-C-08-20 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 295 |
| Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6200, Aquatic (Sediment) Field Dissipation | 2008-10-01 | EPA 712-C-08-21 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 296 |
| Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6300, Forestry Dissipation | 2008-10-01 | EPA 712-C-08-22 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 297 |
| Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6400, Combination and Tank Mixes Field Dissipation | 2008-10-01 | EPA 712-C-08-23 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 298 |
| Ecological Effects Test Guidelines: Field Test Data Reporting Guidelines, 850.6100, Environmental Chemistry Methods and Associated Independent Laboratory Validation (Public draft was numbered 850.7100) | 2012-01-01 | EPA 712-C-12-001 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 271 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4800, Plant Uptake and Translocation Test | 2012-01-01 | EPA 712-C-12-002 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 281 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4900, Terrestrial Soil-Core Microcosm Test | 2012-01-01 | EPA 712-C-12-003 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 282 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4600, Rhizobium-Legume Toxicity | 2012-01-01 | EPA 712-C-12-004 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 280 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4550, Cyanobacteria (Anabaena flos-aquae) Toxicity | 2012-01-01 | EPA 712-C-12-005 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 279 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4500, Algal Toxicity | 2012-01-01 | EPA 712-C-12-006 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 278 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4450, Aquatic Plants Field Study | 2012-01-01 | EPA 712-C-12-007 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 277 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4400, Aquatic Plant Toxicity Test Using Lemna spp. | 2012-01-01 | EPA 712-C-12-008 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 276 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4300, Terrestrial Plants Field Study | 2012-01-01 | EPA 712-C-12-009 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 275 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4230, Early Seedling Growth Toxicity Test | 2012-01-01 | EPA 712-C-12-010 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 274 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4150, Vegetative Vigor | 2012-01-01 | EPA 712-C-12-011 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 273 |
| Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4100, Seedling Emergence and Seedling Growth | 2012-01-01 | EPA 712-C-12-012 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 272 |
| Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3300, Modified Activated Sludge, Respiration Inhibition Test | 2012-01-01 | EPA 712-C-12-014 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 288 |
| Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3200, Soil Microbial Community Toxicity Test | 2012-01-01 | EPA 712-C-12-015 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 287 |
| Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3100, Earthworm Subchronic Toxicity Test | 2012-01-01 | EPA 712-C-12-016 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 286 |
| Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3040, Field Testing for Pollinators | 2012-01-01 | EPA 712-C-12-017 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 285 |
| Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3030, Honey Bee Toxicity of Residues on Foliage | 2012-01-01 | EPA 712-C-12-018 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 284 |
| Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3020, Honey Bee Acute Contact Toxicity Test | 2012-01-01 | EPA 712-C-12-019 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 283 |
| Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2500, Field Testing for Terrestrial Wildlife | 2012-01-01 | EPA 712-C-12-021 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 294 |
| Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2400, Wild Mammal Toxicity Testing | 2012-01-01 | EPA 712-C-12-022 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 293 |
| Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2300, Avian Reproduction Test | 2012-01-01 | EPA 712-C-12-023 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 292 |
| Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2200, Avian Dietary Toxicity Test | 2012-01-01 | EPA 712-C-12-024 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 291 |
| Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2100, Avian Acute Oral Toxicity Test | 2012-01-01 | EPA 712-C-12-025 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 290 |
| Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2000, Background and Special Considerations- Tests with Terrestrial Wildlife | 2012-01-01 | EPA 712-C-12-026 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 289 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1740, Spiked Whole Sediment 10-Day Toxicity Test, Saltwater Invertebrates | 2016-10-01 | EPA 712-C-16-001 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 266 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1735, Spiked Whole Sediment 10-Day Toxicity Test, Freshwater Invertebrates | 2016-10-01 | EPA 712-C-16-002 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 265 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1730, Fish Bioconcentration Factor (BCF) | 2016-10-01 | EPA 712-C-16-003 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 264 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1710, Oyster Bioconcentration Factor (BCF) | 2016-10-01 | EPA 712-C-16-004 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 263 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1300, Daphnid Chronic Toxicity Test | 2016-10-01 | EPA 712-C-16-005 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 259 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1055, Bivalve Acute Toxicity Test | 2016-10-01 | EPA 712-C-16-006 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 257 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1075, Freshwater and Saltwater Fish Acute Toxicity Test | 2016-10-01 | EPA 712-C-16-007 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 258 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1400, Fish Early Life Stage Toxicity Test | 2016-10-01 | EPA 712-C-16-008 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 261 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1045, Penaeid Acute Toxicity Test | 2016-10-01 | EPA 712-C-16-009 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 256 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1025, Oyster Acute Toxicity Test | 2016-10-01 | EPA 712-C-16-010 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 254 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1035, Mysid Acute Toxicity Test | 2016-10-01 | EPA 712-C-16-011 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 255 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1020, Gammarid Amphipod Acute Toxicity Test | 2016-10-01 | EPA 712-C-16-012 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 253 |
| Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1010, Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids | 2016-10-01 | EPA 712-C-16-013 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 252 |
| Ecological Effects Test Guidelines: 850.1000, Background and Special Considerations - Tests with Aquatic and Sediment-Dwelling Fauna and Aquatic Microcosms | 2016-10-01 | EPA 712-C-16-014 | Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 251 |
| Ecological Effects Test Guidelines: Aquatic Fauna Test Guidelines, 850.1500, Fish Life Cycle Toxicity | 1996-04-01 | EPA 712-C-96-122 | Public Draft; Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 269 |
| Ecological Effects Test Guidelines: Aquatic Fauna Test Guidelines, 850.1350, Mysid Chronic Toxicity Test | 1996-04-01 | EPA 712-C-96-166 | Public Draft; Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 268 |
| Ecological Effects Test Guidelines: Aquatic Fauna Test Guidelines, 850.1790, Chironomid Sediment Toxicity Test | 1996-04-01 | EPA 712-C-96-313 | Public Draft; Test Guideline; Ecological Effects | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 270 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1210, Soil Thin Layer Chromatography | 1998-01-01 | EPA 712-C-98-047 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 324 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1220, Sediment and Soil Adsorption/Desorption Isotherm | 1998-01-01 | EPA 712-C-98-048 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 325 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2130, Hydrolysis as a Function of pH and Temperature | 1998-01-01 | EPA 712-C-98-059 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 301 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2210, Direct Photolysis Rate in Water by Sunlight | 1998-01-01 | EPA 712-C-98-060 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 302 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2310, Maximum Direct Photolysis Rate in Air from UV/Visible Spectroscopy | 1998-01-01 | EPA 712-C-98-066 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 304 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3100, Aerobic Aquatic Biodegradation | 1998-01-01 | EPA 712-C-98-075 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 307 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3110, Ready Biodegradability | 1998-01-01 | EPA 712-C-98-076 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 308 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3180, Sediment/Water Microcosm Biogradation Test | 1998-01-01 | EPA 712-C-98-083 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 311 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3200, Zahn-Wellens/EMPA Test | 1998-01-01 | EPA 712-C-98-084 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 313 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3210, Modified SCAS Test | 1998-01-01 | EPA 712-C-98-085 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 314 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3300, Soil Biodegradation | 1998-01-01 | EPA 712-C-98-088 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 320 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3400, Anaerobic Biodegradability of Organic Chemicals | 1998-01-01 | EPA 712-C-98-090 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 321 |
| Fate, Transport and Transformation Test Guidelines: Transformation Chemical-Specific Test Guidelines, 835.5045, Modified SCAS Test for Insoluble and Volatile Chemicals | 1998-01-01 | EPA 712-C-98-097 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 329 |
| Fate, Transport and Transformation Test Guidelines: Transformation Chemical-Specific Test Guidelines, 835.5154, Anaerobic Biodegradation in the Subsurface | 1998-01-01 | EPA 712-C-98-098 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 330 |
| Fate, Transport and Transformation Test Guidelines: Transformation Chemical-Specific Test Guidelines, 835.5270, Indirect Photolysis Screening Test: Sunlight Photolysis in Waters Containing Dissolved Humic Substances | 1998-01-01 | EPA 712-C-98-099 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 331 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3170, Shake Flask Die-Away Test | 1998-01-01 | EPA 712-C-98-297 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 310 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1110, Activated Sludge Sorption Isotherm | 1998-01-01 | EPA 712-C-98-298 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 323 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3220, Porous Pot Test | 1998-01-01 | EPA 712-C-98-301 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 316 |
| Web-Distributed Labeling for Pesticide Products: Pesticide Registration Notice | 2014-01-01 | EPA 705-G-2020-0614 | Pesticide Registration | This Notice presents the Agency's guidance on optional participation in web-distributed labeling for pesticide products. The Agency believes that voluntary adoption of these recommendations by pesticide registrants will help pesticide users to better understand and comply with pesticide labeling. In addition, the Agency believes that web-distributed labeling could allow addition of new uses, modification of existing labeling, and implementation of labeling-based risk mitigation measures more quickly. | 513 |
| PRN 2013-2: Peroxy Compounds Task Force | 2013-11-13 | EPA 705-G-2020-0615 | Pesticide Registration | This PR Notice announces the establishment of the Peroxy Compounds Task Force (PCTF). The PCTF is open to all registrants and applicants with products containing peroxy compounds created to jointly develop data to support registration review under FIFRA. | 429 |
| PRN 2013-1: Silver Task Force North America | 2013-05-01 | EPA 705-G-2020-0616 | Pesticide Registration | This PR Notice announces the establishment of the Silver Task Force North America (STFNA), which was created to jointly develop data to support registration review. | 428 |
| PRN 2012-1: Material Safety Data Sheets as Pesticide Labeling | 2012-01-01 | EPA 705-G-2020-0617 | Pesticide Registration | This Notice updates and clarifies EPA’s determination in PRN 92-4 that a Material Safety Data Sheet that accompanies a pesticide product is considered part of the pesticide’s labeling but does not need EPA approval if it is consistent with 40CFR Part 156. | 426 |
| PRN 2011-3: Standard Format for Data Submitted Under FIFRA and Certain Provisions of FFDCA | 2011-11-30 | EPA 705-G-2020-0618 | Pesticide Registration | This PR Notice updates and replaces Pesticide Registration Notice 86-5 and discusses both the recommended and the required procedures for submitting FIFRA and FFDCA data. | 425 |
| PRN 2011-2: Non-Dietary Exposure Task Force | 2011-11-23 | EPA 705-G-2020-0619 | Pesticide Registration | This PR Notice includes information about an industry-wide task force, the Non-Dietary Exposure Task Force (NDEFT), including how registrants can participate or use data developed by the task force. | 424 |
| PRN 2011-1: Residential Exposure Joint Venture | 2011-01-03 | EPA 705-G-2020-0620 | Pesticide Registration | This PR Notice is to advise registrants of an industry-wide joint venture, titled the Residential Exposure Joint Venture (REJV), which has developed a national survey regarding residential consumer use/usage data for pesticides. | 423 |
| PRN 2009-1: Establishment of Antimicrobial Exposure Assessment Task Force II | 2009-09-30 | EPA 705-G-2020-0621 | Pesticide Registration | This PR notice announces the establishment of the Antimicrobial Exposure Assessment Task Force II, an industry-wide task force to develop mixer, loader, applicator and post-application exposure data for antimicrobial pesticides used in various settings. | 421 |
| PRN 2007-4: Labeling Revisions Required by the Final Rule “Pesticide Management and Disposal; Standards for Pesticide Containers and Containment | 2008-04-29 | EPA 705-G-2020-0622 | Pesticide Registration | This notice provides instructions for implementing the new pesticide product label language required by the new regulations in 40 CFR part 156 established by the Final Rule “Pesticide Management and Disposal; Standards for Pesticide Containers and Containment” (71 FR 47330, August 16, 2006). This notice provides guidance to pesticide registrants on revising their product labels in order to implement the new requirements. Most registrants may be able to make the necessary label amendments by notification; however, in some cases an application for amendment and EPA approval may be required. As specified in the final rule, by August 17, 2009, all pesticide products distributed or sold by a registrant must have labels that comply with the new requirements (40 CFR § 156.159). | 418 |
| PRN 2005-1: Labeling Statements on Products Used for Adult Mosquito Control | 2005-04-15 | EPA 705-G-2020-0624 | Pesticide Registration | This Notice presents the Agency’s guidance on appropriate label language for pesticide products intended for wide-area application to control adult mosquitoes. | 415 |
| PRN 2003-3: Procedural Guidance for EPA's Office of Pesticide Programs Procedures Concerning the Development, Modification, and Implementation of Policy Guidance Documents | 2003-01-01 | EPA 705-G-2020-0625 | Pesticide Registration | EPA’s Office of Pesticide Programs (OPP) will use the procedures in this document for developing, modifying, and implementing its pesticide program policy guidance documents. | 414 |
| PRN 2002-1: Lists of Pests of Significant Public Health Importance | 2002-01-01 | EPA 705-G-2020-0628 | Pesticide Registration | This notice identifies pests of significant public health importance. This list does not, by itself, determine whether a pesticide product might be considered a "public health pesticide“ as that term is used in FIFRA. See Appendix A for the list. | 413 |
| PRN 2001-4: Elimination of Phenol Resistance Testing for Antimicrobial Disinfectant and Sanitizer Pesticides | 2001-01-01 | EPA 705-G-2020-0630 | Pesticide Registration | This Pesticide Registration notice announces the discontinuation of phenol resistance testing as a part of efficacy testing for antimicrobial disinfectants and sanitizers. | 412 |
| PRN 2001-2: Acute Toxicity Data Requirements For Granular Pesticide Products, Including Those With Granular Fertilizers in the Product. | 2001-01-01 | EPA 705-G-2020-0632 | Pesticide Registration | This PR Notice announces guidance intended to streamline the acute toxicity review and classification process for certain granular pesticide products, including those products that contain granular fertilizers. | 411 |
| PRN 2001-1: First Aid Statements on Pesticide Product Labels | 2001-01-01 | EPA 705-G-2020-0633 | Pesticide Registration | This PR notice is intended to provide guidance for what the Agency believes is the most updated appropriate first aid language for pesticide product labels to ensure that they continue to adequately protect the public. | 410 |
| PRN 2000-10: Changes to "Effective Date and Procedures", "Applicability of the Treated Articles Exemption to Antimicrobial Pesticides" | 2000-01-01 | EPA 705-G-2020-0634 | Pesticide Registration | This PR notice addresses the compliance date and other issues related to PR Notice 2000-1, Applicability of the Treated Articles Exemption to Antimicrobial Pesticides. | 405 |
| PRN 2000-8: Reportability of Attorneys’ Opinions and Conclusions Under 40 CFR Part 159 and FIFRA Section 6(a)(2) | 2000-01-01 | EPA 705-G-2020-0635 | Pesticide Registration | EPA is issuing this pesticide registration notice to inform registrants of EPA’s opinion that an attorney’s professional legal judgment is not an opinion or conclusion that is reportable under 40 CFR part 159. | 409 |
| PRN 2000-7: Non-Dietary Exposure Task Force | 2000-01-01 | EPA 705-G-2020-0636 | Pesticide Registration | This PR Notice announces an industry-wide task force to jointly develop residential indoor exposure data for pesticides containing one or more of the active ingredients synthetic pyrethroids, pyrethrum and synergists. | 408 |
| PRN 2000-2: The FIFRA Endangered Species Task Force | 2002-01-01 | EPA 705-G-2020-0655 | Pesticide Registration | This PR Notice announces an industry-wide Task Force that has been formed in response to EPA data requirements related to the potential impact of pesticides on threatened and endangered species. | 406 |
| PRN 98-10: Notifications, Non-Notifications and Minor Formulation Amendments | 1998-01-01 | EPA 705-G-2020-0658 | Pesticide Registration | This Pesticide Registration notice expands the changes to registration that may be made by notification and non-notification, maintains the expedited review of minor formulation changes, and modifies procedures for notifications of antimicrobial products. | 490 |
| PRN 98-9: Modification of Respirator Statements for Pesticide Product Labels | 1998-01-01 | EPA 705-G-2020-0659 | Pesticide Registration | This Pesticide Registration Notice informs registrants of technology improvements for respirators and designation changes for certain respirator filters required in pesticide labeling statements. | 497 |
| PRN 98-6: Flammability Labeling Requirements for Total Release Fogger Pesticides | 1998-01-01 | EPA 705-G-2020-0660 | Pesticide Registration | This notice describes new labeling requirements for total release foggers and provides the procedures and time frame for compliance. It ONLY affects total release foggers containing a propellant with a flash point at or below 20 degrees Fahrenheit. | 495 |
| PRN 98-5: New Forms for the Certification with Respect to Citation of Data | 1998-01-01 | EPA 705-G-2020-0661 | Pesticide Registration | In 1998, EPA established new forms for citation of data to support the registration or reregistration of pesticide products. These forms are EPA Form 8570-34 (“Certification with Respect to Citation of Data”) and 8570-35 (“Data Matrix”). | 494 |
| PRN 98-4: Additional Guidance on Final FIFRA Section 6(a)(2) Regulations for Pesticide Product Registrants w/Attachment | 1998-01-01 | EPA 705-G-2020-0662 | Pesticide Registration | This Pesticide Registration Notice provides guidance on reporting information concerning unreasonable adverse effects of their products to EPA under the regulations promulgated in 1997. | 493 |
| PRN 98-3: Guidance on Final FIFRA 6(a)(2) Regulations for Pesticide Product Registrants | 1998-01-01 | EPA 705-G-2020-0663 | Pesticide Registration | This notice provides registrants comprehensive guidance on implementing the adverse effects reporting regulations that were published in 1997. | 492 |
| Worker Protection Standard Relabeling Process for Retailers and Wholesalers | 1995-10-23 | EPA 705-G-2020-0667 | Pesticide Registration | This is Attachment 1 for Pesticide Registration Notice 95-5, Labeling Revisions Required By The Worker Protection Standard (WPS) for Sale or Distribution of Certain Agricultural Pesticides after October 23, 1995. | 520 |
| PRN 93-1: Statement of Restricted Use Classification | 1993-01-01 | EPA 705-G-2020-0668 | Pesticide Registration | This notice explains EPA's policy on the content and placement of the statement required on the front panel of labeling of pesticides classified for restricted use (RU). | 460 |
| PRN 93-2: Waiver of Crop Field Trial Data for Aerial Applications | 1993-01-01 | EPA 705-G-2020-0673 | Pesticide Registration | This notice is to inform all pesticide registrants that the requirement for crop field trials reflecting aerial applications may be waived under certain circumstances provided adequate data are available on the same crop with use of ground equipment. | 461 |
| PRN 93-3: Labeling Statement Prohibiting Application to Water | 1993-01-01 | EPA 705-G-2020-0674 | Pesticide Registration | This notice explaining the policy on label statement prohibiting pesticide application to water pertains only to the labeling statement on pesticide products. It does not address the term "wetlands" as defined with respect to the Clean Water Act. | 462 |
| PRN 93-4: Ban on Aerosol Products Containing CFCs and HCFCs under the Clean Air Act | 1994-01-01 | EPA 705-G-2020-0675 | Pesticide Registration | This notice alerts pesticide registrants to a rule under the Clean Air Act banning distribution and sale of aerosol and pressurized products, including pesticide products, that contain chlorofluorocarbons (CFCs). | 463 |
| PRN 93-5: Labeling Requirements of the Clean Air Act | 1993-01-01 | EPA 705-G-2020-0676 | Pesticide Registration | A regulation under the Clean Air Act requires a warning statement on products (including pesticide products) manufactured with or containing Class I ozone-depleting substances, including chlorofluorocarbons, methyl chloroform and carbon tetrachloride. | 464 |
| PRN 93-6: False or Misleading Statements Related to Efficacy; Revision of PR Notice 91-7 | 1993-01-01 | EPA 705-G-2020-0677 | Pesticide Registration | This notice clarifies EPA's policy with respect to certain claims of heightened efficacy for pesticide products and supersedes PR Notice 91-7. | 465 |
| PRN 93-7: Labeling Revisions Required by the Worker Protection Standard (WPS) | 1993-01-01 | EPA 705-G-2020-0678 | Pesticide Registration | The Worker Protection Standard (WPS) for agricultural pesticides, issued in August 1992, requires labeling changes for many pesticide end-use products. See guidance to determine what products are affected. | 466 |
| PRN 93-8: Labeling Statement Prohibiting Application to Water; Amendment to PR Notice 93-3 | 1993-01-01 | EPA 705-G-2020-0680 | Pesticide Registration | This notice adds one paragraph to P.R. Notice 93-3, which requested registrants to amend product labeling to include a new labeling statement prohibiting application of a pesticide to water for certain products. | 467 |
| PRN 93-9: Voluntary Reduced-Risk Pesticides Initiative | 1993-01-01 | EPA 705-G-2020-0681 | Pesticide Registration | This PR Notice provides guidance on EPA's voluntary, interim process for identifying pesticides which may be eligible for priority treatment as lower risk products (1993). | 468 |
| PRN 93-10: Effluent Discharge Labeling Statements | 1993-01-01 | EPA 705-G-2020-0682 | Pesticide Registration | This notice describes revised effluent discharge labeling statements required on all manufacturing use products and end use products that may be discharged to waters of the United States or municipal sewer systems. | 458 |
| PRN 93-11: Supplemental Guidance for PR Notice 93-7 - Labeling Revisions Required by the WPS | 1993-01-01 | EPA 705-G-2020-0684 | Pesticide Registration | This pesticide registration notice augments the guidance provided by PR notice 97-3 to provide options that you may choose to allow efficient production and distribution of products that comply with PR Notice 93-7. | 459 |
| PRN 92-1: Requirement to submit and identify adverse effects information | 1992-01-01 | EPA 705-G-2020-0687 | Pesticide Registration | This notice clarifies the Office of Pesticide Program's policy with regard to submission and identification of adverse effects information under FIFRA Section 6(a)(2). | 455 |
| PRN 92-2: Permissible label claims regarding ozone depleting substances | 1992-01-01 | EPA 705-G-2020-0688 | Pesticide Registration | This notice describes EPA's policy for certain chlorofluorocarbon-related labeling claims on pesticide aerosol products. Under this policy, true claims that a product does not contain CFCs or other ozone-depleting substances are permitted on labels. | 456 |
| PRN 92-4: Material Safety Data Sheets as Pesticide Labeling | 1992-01-01 | EPA 705-G-2020-0689 | Pesticide Registration | This notice describes EPA's interpretation that a material safety data sheet may accompany a pesticide or device without approval from EPA as long as it does not conflict with the approved pesticide labeling. | 457 |
| PRN 88-6: Change in Registration Procedures; Agency Approval not Required for Certain Amendments | 1988-01-01 | EPA 705-G-2020-0691 | Pesticide Registration | This notice describes certain modifications to pesticide registrations that no longer require an application to or approval by EPA, based on amendments to 40 CFR 152.44 in May 1988. | 450 |
| PRN 85-6: Clarification of Label Improvement Program for Fumigants. Revision of PR Notice 84-5 | 1985-01-01 | EPA 705-G-2020-0692 | Pesticide Registration | This Pesticide Registration Notice revises and clarifies PR Notice 84-5, related to label changes for fumigant products. | 446 |
| PRN 84-5: Label Improvement Program for Fumigants | 1984-01-01 | EPA 705-G-2020-0693 | Pesticide Registration | This notice required registrants of fumigant products to revise the labeling of products registered under FIFRA section 3 or 24(c) to include additional precautionary statements and other statements described in the notice. | 445 |
| PRN 81-4: Label Improvement Program - Label Revisions to Accommodate New AOAC Methods of Chemical Analysis | 1981-01-01 | EPA 705-G-2020-0694 | Pesticide Registration | This notice describes procedures EPA will use to ensure that pesticide label ingredient statements reflect percentages of ingredients determined by the most specific analytical techniques approved by the Association of Official Analytical Chemists (AOCA). | 441 |
| PRN 80-2: Label Improvement Program: Deletion of Salt Water Emesis Statements | 1980-01-01 | EPA 705-G-2020-0695 | Pesticide Registration | As of 1980, pesticide registrants had to remove salt-water emesis statements from product labels. | 439 |
| PRN 73-4: Residual Insecticides in Food Handling Establishments | 1973-07-06 | EPA 705-G-2020-0696 | Pesticide Registration | This notice provides a copy of a Federal Register notice published July 6, 1973, regarding certain insecticides used in food-handling establishments. It establishes certain definitions and requirements related to approval for crack and crevice treatment. | 437 |
| PRN 70-16: Requirements for Additional Labeling on Products Containing Sodium Hypochlorite | 1970-01-01 | EPA 705-G-2020-0697 | Pesticide Registration | This PR Notice describes additional labeling for pesticide products containing sodium hypochlorite, due to the rapid degradation of the products, to ensure that product effectiveness is maintained. | 435 |
| Improving Labels to Reduce Pesticide Drift | 2014-08-01 | EPA 705-G-2020-0903 | Reducing Pesticide Drift | We encourage pesticide manufacturers to state on their product labels that applicators should use DRT-rated technologies in applying pesticide products. The page includes information on how to obtain approval to add these instructions. | 382 |
| Who Needs to Apply for Pesticide Applicator Certification in Indian Country under the EPA Plan | 2018-09-11 | EPA 705-G-2020-0957 | Pesticide Applicator Certification in Indian Country | Any person who applies restricted use pesticides in an area of Indian country covered by the EPA plan will need a federal certificate from EPA. | 515 |
| Definition of Indian Country | 2018-12-19 | EPA 705-G-2020-0959 | Pesticide Applicator Certification in Indian Country | Definition of Indian Country | 360 |
| PRN 2008-2: Antimicrobial Pesticide Products With Anthrax-Related Claims | 2008-08-26 | EPA 705-G-2020-0960 | Pesticide Registration | This notice provides guidance to prospective applicants of antimicrobial products that make labeling claims to “inactivate Bacillus anthracis (anthrax) spores” (hereafter referred to as “anthrax-related products”). This guidance should help the United States be prepared to respond to incidents involving anthrax spores by assuring that anthrax-related products are registered, that they bear appropriate labeling, and that they are effective when used as directed. In addition, this guidance will help protect public health from the potential risks of anthrax spores by employing terms and conditions of registration that limit the use of anthrax-related products to those who are properly trained and determined to be competent in their use. | 420 |
| PRN 2008-1: Notice to Manufacturers, Producers, Formulators, and Registrants of Pesticide Products | 2008-05-01 | EPA 705-G-2020-0961 | Pesticide Registration | This Notice presents EPA's guidance on optional environmental hazard label language for certain non-restricted use pesticide products intended for outdoor residential use. It clarifies language on how the user can avoid environmental contamination. | 419 |
| PRN 2007-3: The Agricultural Handlers Exposure Task Force, L.L.C | 2007-09-20 | EPA 705-G-2020-0962 | Pesticide Registration | This PR Notice discusses the Agricultural Handlers Exposure Task Force, an industry-wide task force formed to develop mixer, loader, and applicator exposure data for pesticides used in agricultural settings. It includes contacts for more information. | 417 |
| PRN 2007-1: Disposal Instructions on Non-Antimicrobial Residential or Household Use Pesticide Product Labels | 2007-01-01 | EPA 705-G-2020-0970 | Pesticide Registration | This notice is being issued to update and revise PR Notice 2001-6 to clarify that the use of a toll-free number in the disposal instructions on non-antimicrobial residential or household use pesticide product labels is optional. If registrants choose to change or remove a toll-free number from the disposal instructions on their label, this notice provides guidance on making such changes. This notice supersedes PR Notice 2001-6. in its entirety and PR Notices 83-3 and 84-1 in part. See unit VI. | 416 |
| Draft PRN 2006-A: Use of Antimicrobial Pesticide Products in Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R) | 2006-01-01 | EPA 705-G-2020-0972 | Pesticide Registration | This notice provides guidance to registrants of EPA-registered sanitizer, disinfectant and other antimicrobial products whose labels bear general directions for use on or incorporation within hard, non-porous or porous surfaces, but which are not specifically registered for treatment of Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R also referred to as HVAC. Some labels currently use the term HVAC but for reference purposes of this PR Notice, HVAC&R will be used) | 362 |
| PRN 98-8: Waiver of Fees Associated with Tolerance Objections | 1998-01-01 | EPA 705-G-2020-0988 | Pesticide Registration | EPA's regulations require that tolerance objections be accompanied by a filing fee of $3,275. This fee can be waived. This notice clarifies EPA's interpretation of the regulation. | 496 |
| PRN 98-2: Liquid Chemical Sterilant Products | 1998-01-01 | EPA 705-G-2020-0989 | Pesticide Registration | Liquid chemical sterilant products are no longer regulated as "pesticides" by the Environmental Protection Agency (EPA), but as "medical devices" under the regulatory authority of the Food and Drug Administration (FDA). | 491 |
| PRN 97-9: Electronic Submission Of Child-Resistant Packaging Test Data For All Pesticides | 1997-01-01 | EPA 705-G-2020-0990 | Pesticide Registration | This pesticide registration notice addresses four issues related to child-resistant packaging. | 489 |
| PRN 97-7: Existing Stocks for Labeling Changes in PR Notices | 1997-01-01 | EPA 705-G-2020-0992 | Pesticide Registration | EPA intends to establish October 1 as the annual compliance date for most EPA-initiated label changes specified by a PR Notice, FR Notice or similar mechanism. We will allow at least one year for an action to become effective. Other dates may apply. | 488 |
| PRN | 1997-01-01 | EPA 705-G-2020-0997 | Pesticide Registration | This is a list of common names for use on pesticide Labels approved by The American National Standards Institute. | 500 |
| PRN 97-5 Appendix B | 1997-01-01 | EPA 705-G-2020-0999 | Pesticide Registration | Appendix B lists other names, not established by ANSI, which may also be used alone in the ingredients statement without an accompanying chemical name. | 487 |
| PRN 97-4: Consumer Access Numbers on Pesticide Labels | 1997-01-01 | EPA 705-G-2020-1015 | Pesticide Registration | This notice describes EPA policy on including telephone numbers and other access numbers or internet addresses, on pesticide product labeling. It also explains how the telephone number of the National Pesticide Information Center hotline may be used. | 486 |
| PRN 97-3: Guidelines for Expedited Review of Conventional Pesticides under the Reduced-Risk Initiative and for Biological Pesticides | 1997-01-01 | EPA 705-G-2020-1017 | Pesticide Registration | EPA encourages the development, registration and use of lower-risk pesticide products which would result in reduced risks to human health and the environment. This Pesticide Registration notice and the related web page explain the process and criteria. | 485 |
| PRN 97-1: Agency Actions under the Requirements of the Food Quality Protection Act | 1997-01-01 | EPA 705-G-2020-1018 | Pesticide Registration | This pesticide registration notice describes EPA's implementation of the Food Quality Protection Act, including the risk cup and risk management strategies under the new safety standard. | 484 |
| PRN 96-7: Termiticide Labeling | 1996-01-01 | EPA 705-G-2020-1021 | Pesticide Registration | This notice sets forth the Agency's policy with respect to certain labeling statements and minimum product performance (5 year period) for soil treatment termiticide products. | 483 |
| PRN Notice 96-6: Pet Pesticide Product Label Statements | 1996-01-01 | EPA 705-G-2020-1022 | Pesticide Registration | This notice specifies statements that should be added to the labels of pesticide products registered for use on dogs and/or cats. These label statements will help to ensure that products bear labeling to reduce the potential for misuse of pet products. | 499 |
| PRN 96-4: Label Statements Involving Product Efficacy and Potential for Harm to Property | 1996-01-01 | EPA 705-G-2020-1023 | Pesticide Registration | This notice explains EPA procedures in approving pesticide labels that include claims relating to the efficacy of agricultural pesticides and provides a warning to growers regarding reliance on label statements regarding pesticide efficacy. | 482 |
| PRN 96-3: Pesticide Products Used to Disinsect Aircraft | 1996-01-01 | EPA 705-G-2020-1024 | Pesticide Registration | This Notice specifies labeling changes for any pesticide product (insecticide) used for disinsecting aircraft. EPA required these changes based on incident information associated with the use of insecticide spray products occupied aircraft cabins. | 481 |
| PRN 96-2: Changes to Child-Resistant Packaging (CRP) Testing Requirements | 1996-01-01 | EPA 705-G-2020-1025 | Pesticide Registration | This pesticide registration notice announced revisions to the effectiveness standards applicable to child-resistant packaging (CRP). | 480 |
| PRN 96-1: Tolerance Enforcement Methods - Independent Laboratory Validation by Petitioner | 1996-01-01 | EPA 705-G-2020-1026 | Pesticide Registration | This notice is intended to clarify the requirements for submission of an Independent Laboratory Validation to accompany new pesticide analytical methods and does not contain additional data requirements. This notice supersedes PR Notice 88-5. | 479 |
| PRN 95-5: Labeling Revisions Required By The Worker Protection Standard (WPS) For Sale Or Distribution Of Certain Agricultural Pesticides After October 23,1995 | 1995-01-01 | EPA 705-G-2020-1027 | Pesticide Registration | This notice provides guidance to people who sell or distribute pesticides on meeting requirements for labeling under the worker protection standard (1992 version). | 478 |
| PRN 95-3: Reduction of Worker protection Standard (WPS) Interim Restricted Entry Intervals (REIS) for Certain Low Risk Pesticides | 1995-05-03 | EPA 705-G-2020-1028 | Pesticide Registration | On January 11, 1995, EPA published a draft policy on "Reduced Restricted Entry Intervals for Certain Pesticides," in the Federal Register. The final policy was published in the Federal Register on May 3, 1995. This Notice contains the final policy. | 477 |
| PRN 95-1: Effluent Discharge Labeling Statements | 1995-01-01 | EPA 705-G-2020-1029 | Pesticide Registration | This notice exempts certain pesticide products from bearing effluent discharge labeling statements specified by P.R. Notice 93-10 for manufacturing use products and end use products that may be discharged to waters of the U.S. or municipal sewer systems. | 476 |
| PRN 94-9: Announcing the Formation of Two Industry-Wide Task Forces: Agricultural Reentry Task Force and Outdoor Residential Exposure Task Force | 1994-01-01 | EPA 705-G-2020-1030 | Pesticide Registration | This Notice announces two industry-wide Task Forces being formed in response to generic exposure data requirements. It contains EPA's policy on a registrant's options for, and responsibilities when joining Task Force as a way to satisfy data requirements. | 475 |
| PRN 94-8: Water Soluble Packaging (WSP) | 1994-01-01 | EPA 705-G-2020-1031 | Pesticide Registration | This notice describes the registration requirements for pesticide products containing water soluble packaging (WSP). | 474 |
| PRN 94-7: Label Improvement Program for the Revision of Use Directions for Commensal Rodenticides and Statement of the Agency's Policies on the Use of Rodenticide Bait Stations | 1994-01-01 | EPA 705-G-2020-1032 | Pesticide Registration | This Notice requires registrants of certain pesticide products claimed to control commensal rodents and registered under FIFRA to revise the labeling of such products to bear certain statements concerning "tamper-resistant bait stations." | 473 |
| PRN 94-6: Pesticide Products Registered for Use on Humans to Control Lice (Pediculicides) | 1994-01-01 | EPA 705-G-2020-1034 | Pesticide Registration | This notice alerts pesticide registrants to a rule issued by Food and Drug Administration (FDA) under the Federal Food, Drug and Cosmetic Act (FFDCA) establishing conditions for safe and effective use of pediculicide drug products. | 472 |
| PRN 94-5: Requests for Re-considerations of Carcinogenicity Peer Review Decisions Based on Changes in Pathology Diagnoses | 1994-01-01 | EPA 705-G-2020-1036 | Pesticide Registration | This notice sets forth a procedure to be followed for submission of pathology re-reads to the Agency. | 471 |
| PRN Notice 94-4: Interim Measures for the Registration of Antimicrobial Products/Liquid Chemical Germicides with Medical Device Use Claims Under the Memorandum of Understanding Between EPA and FDA | 1994-01-01 | EPA 705-G-2020-1037 | Pesticide Registration | This Notice is intended to provide the regulated community with detailed guidance on the interim EPA registration procedures for antimicrobial products affected by the June 4, 1993, Memorandum of Understanding (MOU) between EPA and FDA. | 498 |
| PR Notice 94-4 MOU on Regulation of Liquid Chemical Germicides Intended for Use on Medical Devices | 1994-01-01 | EPA 705-G-2020-1039 | Pesticide Registration | This MOU between EPA and FDA establishes roles for regulation of liquid chemical germicides intended for use on medical devices. An amendment revises the disclaimer statement for labels of all liquid chemical germicides, other than FDA-approved sterilants. | 399 |
| PRN 94-2: Recycling Empty Aerosol Pesticide Containers | 1994-01-01 | EPA 705-G-2020-1040 | Pesticide Registration | This notice offers registrants use of an optional label statement permitting recycling as an alternative to instructions to dispose of aerosol pesticide containers. Registrants may add a label reference to recycling the empty aerosol pesticide container. | 470 |
| PRN 94-1: Withdrawal of PR Notice 91-8 | 1994-01-01 | EPA 705-G-2020-1041 | Pesticide Registration | EPA withdrew PR Notice 91-8, entitled "Revised Policy To Provide Applicants Other Than Basic Manufacturers An Opportunity To Submit Generic Data and Receive Data Compensation For It." | 469 |
| PRN 91-1: Procedures for Voluntarily Requesting Deletion of Approved Uses from Registered Labels | 1991-01-01 | EPA 705-G-2020-1042 | Pesticide Registration | This pesticide registration notice defines procedures for registrants to use when they want to request an amendment to delete one or more uses from an approved registration, and it summarizes the actions the Agency will take in response to such requests. | 453 |
| PRN 91-2: Accuracy of Stated Percentages for Ingredients Statement | 1991-01-01 | EPA 705-G-2020-1043 | Pesticide Registration | The purpose of this notice is to clarify the Office of Pesticide Program's policy with respect to the statement of percentages in a pesticide's label's ingredient statement. | 454 |
| PRN 90-3: Announcing the Formation of an Industry-Wide Spray Drift Task Force | 1990-01-01 | EPA 705-G-2020-1044 | Pesticide Registration | "A Spray Drift Task Force has been organized pursuant to provisions of FIFRA section 3 (c)(2)(B)(ii) to share the cost of developing a generic spray drift data base capable of satisfying spray drift data requirements for pesticide product registrations. | 452 |
| PRN 90-1: Inert Ingredients in Pesticide Products; Revised Policy Statement | 1990-01-01 | EPA 705-G-2020-1045 | Pesticide Registration | This notice discusses compliance with Federal Register Notice (54 FR 58314; November 22, 1989). | 451 |
| PRN 87-6: Inert Ingredients in Pesticide Products; Policy Statement | 1987-01-01 | EPA 705-G-2020-1047 | Pesticide Registration | This PR notice announces certain policies regarding inert ingredients in pesticide products, including amendments required for products containing inert ingredients of toxicological concern. | 448 |
| PRN 87-1: Label Improvement Program for Pesticides Applied through Irrigation Systems (Chemigation) | 1987-01-01 | EPA 705-G-2020-1048 | Pesticide Registration | This Notice requires registrants of pesticide products registered under FIFRA and applied through irrigation systems to revise the labeling for such products to include additional use directions and other statements described in this Notice. | 447 |
| Pesticide Registration (PR) Notice 87-1 MOU | 1987-01-01 | EPA 705-G-2020-1053 | Pesticide Registration | These documents provide more information related to implementation of Pesticide Registration Notice 87-1, which addresses label improvement for pesticides applied through irrigation systems. | 388 |
| PRN 84-1: Clarification of Label Improvement Program for Farmworker Safety and Pesticide Storage and Disposal Instructions | 1984-01-01 | EPA 705-G-2020-1054 | Pesticide Registration | This PR notice clarifies EPA's intentions regarding the Pesticide Label Improvement Program for Farmworker Safety (PR Notice 83-2) and Pesticide Storage and Disposal Instructions (PR Notice 83-3) issued on March 26, 1983. | 444 |
| PRN 83-3: Label Improvement Program - Storage and Disposal Label Statements | 1983-01-01 | EPA 705-G-2020-1058 | Pesticide Registration | This Notice is to inform all registrants that the label of all pesticide products must include updated storage and disposal statements. No application for amended registration is required if you use the exact wording contained in this Notice. | 443 |
| PR Notice 83-3 Appendix B | 1983-01-01 | EPA 705-G-2020-1059 | Pesticide Registration | This appendix to PR Notice 83-3 lists pesticides that are hazardous waste under 40 CFR 261, 33(e) and (f) when discarded. | 398 |
| PRN 82-1: Revised Policy on Label Claims for Tank Mixing | 1982-01-01 | EPA 705-G-2020-1061 | Pesticide Registration | This notice sets out EPA's policy related to claims for tank mixing a pesticide product with another pesticide product. | 442 |
| Pesticide Containers | 2019-12-03 | EPA 705-G-2020-1276 | Pesticide Worker Safety | The pesticide container regulations establish standards for pesticide containers, repackaging, label instructions and to ensure safe use, reuse and disposal and adequate cleaning of the containers. | 386 |
| Rinsing Procedures for Dilutable Pesticide Products in Rigid Containers | 2008-06-25 | EPA 705-G-2020-1277 | Pesticide Worker Safety | The pesticide container regulations establish standards for pesticide containers, repackaging, label instructions and to ensure safe use, reuse and disposal and adequate cleaning of the containers. | 503 |
| Frequently Asked Questions on the Container and Containment Labeling Requirements | 2019-08-27 | EPA 705-G-2020-1278 | Pesticide Worker Safety | Frequently Asked Questions on the Container and Containment Labeling Requirements | 375 |
| Buoyant Force Calculations | 2016-08-24 | EPA 705-G-2020-1279 | Pesticide Worker Safety | Find out how buoyant force calculations are used to determine if a secondary containment unit complies with the pesticide containment regulations. | 356 |
| Interim Policy for Repair of Pesticide Containers | 2009-10-09 | EPA 705-G-2020-1280 | Pesticide Worker Safety | EPA will consider on a case-by-case basis whether to allow repair of minor damage to pesticide containers in the retail environment. Find out more about how EPA is implementing this policy. | 383 |
| Pesticide Containment Structures | 2019-11-12 | EPA 705-G-2020-1282 | Pesticide Worker Safety | Learn about federal and state requirements for pesticide containment structures. | 387 |
| Scope of the Federal Pesticide Containment Regulations | 2009-12-01 | EPA 705-G-2020-1283 | Pesticide Worker Safety | The purpose of this document is to help you determine whether the federal containment regulations require you to have a secondary containment unit and/or a containment pad. | 504 |
| Clarification of PR Notice 2003-1 | 2015-06-11 | EPA 705-G-2020-1287 | Pesticide Registration | This document clarifies when and how the National Organic Program logo may be used on pesticide products and how to obtain approval to add it. | 358 |
| Scope of the Non-refillable Container, Refillable Container, and Repackaging Regulations for Pesticide Containers | 2016-08-24 | EPA 705-G-2020-1291 | Pesticide Worker Safety | Two flow charts: Scope of container and repackaging regulations and determining whether Antimicrobial products are exempt from or subject to regulations. | 505 |
| EPA Pesticide Container and Repackaging Regulations - Flow Chart 1 | 2012-04-27 | EPA 705-G-2020-1292 | Pesticide Worker Safety | Flow Chart 1: Is this container a service container or a portable refillable container? | 364 |
| EPA Pesticide Container and Repackaging Regulations - Flow Chart 2 | 2012-04-27 | EPA 705-G-2020-1293 | Pesticide Worker Safety | A flowchart which diagrams the question "Can I fill this large portable refillable container (greater than 119 gallons)? | 365 |
| EPA Pesticide Container and Repackaging Regulations - Flow Chart 3 | 2012-04-27 | EPA 705-G-2020-1294 | Pesticide Worker Safety | Flow Chart 3: Can I fill this small portable refillable container | 366 |
| Generic Verification Protocol for Testing Pesticide Application Spray Drift Reduction Technologies for Row and Field Crops | 2017-01-01 | EPA 705-G-2020-1361 | Reducing Pesticide Drift | This generic verification protocol provides a detailed method to conduct and report results from a verification test of pesticide application technologies that can be used to evaluate these technologies for their potential to reduce spray drift. | 376 |
| PRN 88-2: Clustering of Quaternary Ammonium Compounds | 1988-02-26 | EPA 705-G-2020-1420 | Pesticide Registration | This Notice announces that EPA has clustered the Quaternary Ammonium Compounds into four groups for the purpose of testing chemicals to build a database that will support continued registration of the entire family of quaternary ammonium compounds | 449 |
| PRN 75-5: Unacceptable Use of the Word "Chlorine" in the Name and Labeling of Pesticides | 1975-01-01 | EPA 705-G-2020-1423 | Pesticide Registration | Use of the word "Chlorine" on labels other than in products containing liquefied chlorine under pressure has been determined to be in violation of Section 2(q)(l)(A) of the Federal Insecticide, Fungicide, and Rodenticide Act. | 438 |
| PRN 67-5 Economic Poisons Containing Sodium Hypochlorite | 1967-09-26 | EPA 705-G-2020-1424 | Pesticide Registration | Products containing sodium hypochlorite at various concentrations have been accepted for registration under the Federal Insecticide, Fungicide, and Rodenticide Act. | 434 |
| PRN 66 Federal Registration of Economic Poisons | 1966-11-16 | EPA 705-G-2020-1425 | Pesticide Registration | The Federal Insecticide, Fungicide, and Rodenticide Act, and the regulations promulgated thereunder, provide that an economic poison is misbranded if its labeling bears any statement, graphic representation, or design which is false or misleading. | 433 |
| Guidance on Basic Elements of an EPA-Funded Tribal Pesticide Program | 2017-03-25 | EPA 705-G-2020-1475 | Pesticide Advisory Committees and Regulatory Partners | This guidance document describes basic elements for an EPA-funded tribal pesticide program. | 377 |
| NAFTA Guidance on Data Requirements for Pesticide Import Tolerances: Questions & Answers | 2018-01-01 | EPA 705-G-2020-1476 | Pesticide Tolerances | These Q&A's provide details of implementation related to a guidance document describing the data requirements for establishing pesticide import tolerances in Canada and the United States: NAFTA Guidance on Data Requirements for Pesticide Import Tolerances. | 384 |
| PRN 1982-2 Change in Procedures for Approval of Applications | 1982-06-18 | EPA 705-G-2020-1506 | Pesticide Registration | This Notice revises EPA procedures with respect to submission of final printed labeling and agreement to conditions of registration. | 404 |
| Worker Protection Standard Application Exclusion Zone | 2023-02-16 | EPA 705-G-2020-1521 | Pesticide Worker Safety | These documents provide general guidance to help you comply with the requirements of the Federal Worker Protection Standard (WPS) for agricultural pesticides, 40 CFR part 170, as amended in 2015. | 517 |
| Worker Protection Standard Train-the-Trainer Programs, Approval Process and Criteria | 2017-08-01 | EPA 705-G-2020-1573 | Pesticide Worker Safety | EPA has prepared guidance material to facilitate the development of Train-the-Trainer programs that meet EPA requirements. | 521 |
| PRN 2017-2: Guidance for Herbicide-Resistance Management, Labeling, Education, Training, and Stewardship | 2017-01-01 | EPA 705-G-2020-1711 | Pesticide Registration | Provides 11 elements focused on labeling, education, training and stewardship strategies. | 431 |
| Pesticide Worker Protection Standard “How to Comply” Manual | 2016-09-30 | EPA 705-G-2020-1750 | Pesticide Worker Safety | The “How to Comply” manual provides information for employers on complying with the worker protection standard for agricultural workers. It has been updated to cover the 2015 revisions to the WPS. | 389 |
| FIFRA Pesticides Export Policy: Questions & Answers | 2019-05-21 | EPA 705-G-2020-2509 | FIFRA exports | questions and answers are intended to assist in compliance with the Environmental Protection Agency's February 18, 1993 rule (58 FR 9062) regarding the exportation of pesticides. | 373 |
| FIFRA Pesticides Export Policy: Questions & Answers Issue: Research and Development Pesticides; Active Ingredient Concentrations | 2017-02-28 | EPA 705-G-2020-2510 | FIFRA exports | questions and answers are intended to assist in compliance with the Environmental Protection Agency's February 18, 1993 rule (58 FR 9062) regarding the exportation of pesticides. | 374 |
| Web-distributed Labeling for Pesticides | 2014-01-01 | EPA 705-G-2020-2511 | Pesticide Labeling | Additional information on PR Notice 2014-1 including history of development, examples, and Q&As | 514 |
| Worker Protection Standard Frequently Asked Questions 40 CFR Part 170 | 2016-04-14 | EPA 705-G-2020-2523 | Pesticide Worker Safety | Frequently asked questions and answers related to the WPS rule change in 2015 - published in April 2016. | 519 |
| Worker Protection Standard Application Exclusion Zone Requirements Updated Question and Answers | 2018-02-15 | EPA 705-G-2020-2524 | Pesticide Worker Safety | This fact sheet contains further explanation of the Application Exclusion Zone (AEZ) requirement in the Agricultural Worker Protection Standard WPS. | 518 |
| Revising Certification Plans to Meet the Requirements of the 2017 Certification of Pesticide Applicators Final Rule Questions & Answers | 2019-08-23 | EPA 705-G-2020-2525 | Certification of Pesticide Applicators | This document is intended for pesticide State Lead Agencies (SLAs), Tribes and Federal Agencies (“certifying authorities”) to answer their questions on the 2017 Certification of Pesticide Applicators regulation and the requirement to submit to EPA revised certification plans by March 4, 2020. | 502 |
| State Certification Plan Outline | 2019-04-29 | EPA 705-G-2020-2526 | Certification of Pesticide Applicators | This document serves as a model outline for the order and contents of state certification plans. | 508 |
| Qs and As from Federal Agencies on Federal Agency Certification Plans | 2019-08-28 | EPA 705-G-2020-2527 | Certification of Pesticide Applicators | This document is intended to answer Federal agency questions on the 2017 Certification of Pesticide Applicators regulation. | 501 |
| Federal Agency Certification Plan Outline | 2019-08-28 | EPA 705-G-2020-2528 | Certification of Pesticide Applicators | This document is intended to answer Federal agency questions on the 2017 Certification of Pesticide Applicators regulation. | 370 |
| Tribal Certification Plan Outline | 2019-09-18 | EPA 705-G-2020-2529 | Certification of Pesticide Applicators | This document serves as a model outline for the order and contents of a tribal certification plan for those tribes that choose to develop their own certification plan under 40 CFR § 171.307(b). | 512 |
| Certification of Pesticide Applicators in Indian Country: Fact Sheet on Certification Options Available to Federally Recognized Tribes | 2019-02-05 | EPA 705-G-2020-2531 | Certification of Pesticide Applicators | The purpose of this document is to inform federally recognized tribal governments and pesticide regulatory agencies of new requirements for tribal certified applicator plans and EPA’s intent to propose revisions to the EPA Plan for the Federal Certification of Applicators of Restricted Use Pesticides within Indian Country (i.e., EPA Plan) and associated options. | 357 |
| PRN 2012-X; Draft; Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims. Docket ID EPA-HQ-OPP-2010-0539 | 2012-12-12 | EPA 705-G-2020-2661 | Pesticide Registration | Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims. Docket ID EPA-HQ-OPP-2010-0539 | 427 |
| PRN 2010-X; Draft; Proposed Guidance on False or Misleading Pesticide Product Brand Names | 2010-01-01 | EPA 705-G-2020-2662 | Draft; PRN; Draft PRN; PRN 2010-x; 2010 | Proposed Guidance on False or Misleading Pesticide Product Brand Names. | 422 |
| PRN 81-3; Label Improvement Program: Change in Test Methods for and Categorization of Eye Irritation | 1981-01-01 | EPA 705-G-2020-2670 | PRN | Label Improvement Program: Change in Test Methods for and Categorization of Eye Irritation | 440 |
| PRN 72-6; Changes in standard for expressing potency of products containing Bacillus Truringiensis Berliner | 1972-01-01 | EPA 705-G-2020-2671 | EPA Archive | Changes in standard for expressing potency of products containing Bacillus Truringiensis Berliner | 436 |
| PRN 2000-6; Minimum Risk Pesticides Exempted under FIFRA Section 25(b) Clarification of Issues | 2000-01-01 | EPA 705-G-2020-2672 | Pesticide Registration | Minimum Risk Pesticides Exempted under FIFRA Section 25(b) Clarification of Issues Web information posted in January 2015: Minimum Risk Pesticides Exempted from FIFRA Registration supersedes this PR notice | 407 |
| FIFRA Pesticides Export Policy Interpretative Guidance Issue: Multilingual Labeling | 1993-04-08 | EPA 705-G-2020-2769 | FIFRA Pesticides Export Policy | This document addresses the requirement that certain labeling statements appear in English and in the languages of destination countries if known or reasonably ascertainable by the exporter. | 372 |
| Secondary Containers and Service Containers for Pesticides | 2015-10-26 | EPA 705-G-2020-2886 | container; labels | Explains what secondary containers and service containers are; EPA does not require labels on them; and, provides EPA recommendations for them. | 506 |
| Table 4: Refillable container Requirements (40 CFR Part 165 Subpart C) | 2008-10-01 | EPA 705-G-2020-2908 | Refillable Container | refillable container requirements | 510 |
| Pesticide Container and Repackaging Standards | 2015-06-01 | EPA 705-G-2020-2910 | Container/Repackaging | Scope of the Non-refillable Container, Refillable Container, and Repackaging Regulations for Pesticide Containers | 385 |
| Simple Comparison of the Major 2016 Revisions to the Existing Rule | 2017-01-12 | EPA 705-G-2020-2912 | Certification of Pesticide Applicators | Comparison tables of the 2016 revisions to the Certification of Pesticide Applicator Rule to the existing rule. | 507 |
| Detailed Comparison of the 2016 Revisions to the Existing Rule | 2016-12-30 | EPA 705-G-2020-2913 | Certification of Pesticide Applicators | Comparison tables of the 2016 revisions to the Certification of Pesticide Applicator Rule to the existing rule. | 361 |
| How to Get Certified as a Pesticide Applicator | 2018-11-15 | EPA 705-G-2020-2990 | Certification of Pesticide Applicators | Information on what someone needs to do to get certified as a pesticide applicator. | 381 |
| Federal Certification Standards for Pesticide Applicators | 2018-04-02 | EPA 705-G-2020-2991 | Certification of Pesticide Applicators | Information on the standards for applicators. | 371 |
| Exporting Unregistered Pesticides: Foreign Purchaser Acknowledgement Statements | 2020-01-01 | EPA 705-G-2020-3590 | FIFRA Export Policy | This website provides guidance to companies intending to export unregistered pesticides to promote compliance assistance with FIFRA Sec. 17(a) and related regulations at 40 CFR 168.75) | 369 |
| Guidance to Submit A Pesticide Petition | 2018-03-01 | EPA 705-G-2020-3591 | Pesticide Petition | EPA offers a number of ways for the public to participate in and comment on regulatory actions that the agency proposes to take regarding the registration and review of pesticides. This webpage identifies those opportunities, including guidance on how to submit a pesticide petition. | 380 |
| Worker Protection Standard (WPS) Comparison Chart: Comparison of the Revised Protections to the Previous Protections | 2017-01-01 | EPA 705-G-2020-3594 | Pesticide Worker Safety | This table summarizes key provisions in the EPA’s previous WPS regulation and the 2015 revisions. | 516 |
| CPARD USER GUIDE: For State Lead Agency (SLA) and Tribal Representatives with Certification Plans (CPs) | 2019-11-01 | EPA 705-G-2020-3686 | Certification of Pesticide Applicators | The Certification Plan and Reporting Database (CPARD) is a compilation of EPA?approved pesticide applicator certification plans and reporting as required by the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) and the federal Certification of Pesticide Applicators regulations at 40 CFR Part 171. In 2019, EPA added a section (Certification 2020) on the review and approval of modified certification plans due to EPA by March 4, 2020. This guide describes how to register and use CPARD. | 359 |
| Statement Regarding Respiratory Protection Shortages and Reduced Availability of Respirator Fit Testing Related to Pesticide Uses Covered by the Agricultural Worker Protection Standard during the COVID-19 Public Health Emergency | 2020-06-01 | EPA 705-G-2020-3699 | Pesticides, FIFRA, worker protection | The EPA has developed this document with the goal of continuing to protect the health of pesticide handlers while acknowledging the challenges that handler employers and pesticide handlers may face with respect to personal protective equipment (PPE) | 509 |
| Guidance on Satisfying the Annual Pesticide Safety Training Requirement under the Agricultural Worker Protection Standard during the COVID-19 Emergency | 2020-06-18 | EPA 705-G-2020-3700 | FIFRA, pesticides, worker protection | This temporary guidance addresses pesticide safety training of farmworkers and pesticide handlers in agriculture as required by the Agricultural Worker Protection Standard (WPS) (40 CFR 170). EPA is clarifying that pesticide safety training may be presented remotely, provided all of the WPS training requirements are met. | 378 |
| Guidance regarding the Certification of Pesticide Applicators during the COVID-19 Public Health Emergency | 2020-07-27 | EPA 705-G-2020-3719 | FIFRA, Certification of Pesticide Applicators | To help states, tribes, and federal certifying authorities meet both the needs of applicators and the requirements of the Certification of Pesticide Applicators (CPA) rule (40 CFR Part 171) during this COVID-19 PHE, EPA has developed this guidance based on certifying authorities’ input. | 379 |
| Pesticide Submission Portal - Quick Reference Guide - Foreign Purchasers Acknowledgement Statements (FPAS) | 2021-08-17 | EPA 705-G-2021-3738 | FIFRA; CDX | CDX user guide for submitting Foreign Purchasers Acknowledgement Statements. | 1013 |
| PR Notice 2000-1; Applicability of the Treated Articles Exemption to Antimicrobial Pesticides | 2000-03-06 | PR Notice 2000-1 | Pesticide Registration Notices by Year | This notice clarifies EPA policy with respect to the scope of the "treated articles exemption" in 40 CFR 152.25(a). This exemption covers qualifying treated articles and substances bearing claims to protect the article or substance itself. EPA does not regard this exemption as including articles or substances bearing implied or explicit public health claims against human pathogens. | 391 |
| PR Notice 2000-5; Guidance for Mandatory and Advisory Labeling Statements | 2000-05-10 | PR Notice 2000-5 | Pesticide Registration Notices by Year | This notice provides guidance to the registrant for improving the clarity of labeling statements in order to avoid confusing directions and precautions, and to prevent the misuse of pesticides. | 392 |
| PR Notice 2001-3; Insect Repellents: Labeling Restrictions for Use on Infants and Children and Restrictions on Food Fragrances and Colors | 2001-01-16 | PR Notice 2001-3 | Pesticide Registration Notices by Year | This notice announces EPA's approach to insect repellents bearing claims for use specifically on infants and children. EPA believes that the label changes and policy clarification set forth in this PR Notice will reduce risks associated with the improper use of insect repellents and will improve consumer understanding. Additionally, this PR Notice states EPA's current position on insect repellents formulated to contain colors and fragrances predominantly associated with food (e.g., grape, watermelon, or orange). | 393 |
| PR Notice 2001-5; Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling | 2001-06-19 | PR Notice 2001-5 | Pesticide Registration Notices by Year | This archived PRN provided guidance for pesticide registrants on pesticide resistance management labeling that has since been superseded. | 394 |
| PR Notice 2002-2; Guidance for Submitting Requests for Threshold of Regulation Decisions to OPP | 2002-08-20 | PR Notice 2002-2 | Pesticide Registration Notices by Year | In the Federal Register of October 27, 1999 (64 FR 57881), the Environmental Protection Agency (EPA) announced the availability of a document entitled “Threshold of Regulation Policy - Deciding Whether a Pesticide with a Food Use Pattern Needs a Tolerance.” The Threshold of Regulation (TOR) Policy describes criteria and procedures to be considered in determining whether a use of a pesticide in a location and manner that has the possibility of resulting in residues in food is below the threshold of regulation. | 395 |
| PR Notice 2003-1; Labeling of Pesticide Products under the National Organic Program | 2003-01-31 | PR Notice 2003-1 | Pesticide Registration Notices by Year | This notice describes how registrants can obtain EPA approval of label language indicating that all ingredients (active and inert) in a pesticide product and all uses of that pesticide meet the criteria defined in the United States Department of Agriculture’s National Organic Program Rule. This Pesticide Registration Notice provides an example of acceptable label language and the procedures for adding such identification to product labels. The information on the pesticide label will assist organic growers and those persons certifying organic production methods in knowing which pesticide products meet the requirements of the NOP Rule for use in organic agriculture. | 396 |
| PR Notice 2007-2: Guidance on Small-Scale Field Testing and Low-level Presence in Food of Plant-Incorporated Protectants (PIPs | 2007-04-30 | PR Notice 2007-2 | Pesticide Registration Notices by Year | This PR Notice provides clarification on the process by which EPA reviews and ensures the safety of residues of plant-incorporated protectants (PIPs) potentially present at low levels in food or feed, and the conditions under which a tolerance or exemption from the requirement of a tolerance would be required for field tests for biotechnology-derived food and feed crop plants containing plant-incorporated protectants. | 397 |
| PR (Pesticide Registration) Notice 96-8; Toxicologically Significant Levels of Pesticide Active Ingredients | 1996-10-31 | PR Notice 96-8 | Pesticide Registration Notices by Year | This notice sets out EPA's interpretation of the term "toxicologically significant" as it applies to contaminants in pesticide products that are also pesticide active ingredients. This notice provides risk-based concentration levels of such contaminants that will generally be considered toxicologically significant. These concentrations are defined according to the type of pesticide that is contaminated and the pesticide category of the contaminant. | 390 |
| PR Notice 97-5; Use of Common Names for Active Ingredients on Pesticide Labeling | 1997-09-11 | PR Notice 97-5 | Pesticide Registration Notices by Year | This notice announces EPA policy to expand the use of common names on pesticide labeling. EPA will permit the use of common names approved by the American National Standards Institute (ANSI) in the label ingredients statement without the accompanying scientific chemical names, and will permit the use of other common names listed in this notice without the accompanying scientific chemical name. EPA also recommends the inclusion on labels of Chemical Abstracts Service (CAS) numbers to identify ingredients definitively. | 400 |
| PR Notice 97-6; Use of Term "Inert" in the Label Ingredients Statement | 1997-09-11 | PR Notice 97-6 | Pesticide Registration Notices by Year | This notice announces a change in EPA policy regarding the label ingredients statement. Effective immediately, the phrase "Inert ingredients," may be replaced by the term "Other ingredients." Although no registrant is required to make this change, EPA encourages registrants to do so. Provided the term "Other ingredients" is used, the change may be made at any time without notification to the Agency. | 401 |
| PR Notice 98-1; Self-Certification of Product Chemistry Data | 1998-01-12 | PR Notice 98-1 | Pesticide Registration Notices by Year | The Office of Pesticide Programs has established a self-certification program for certain product chemistry data of manufacturing-use products and end-use products produced by a non-integrated formulation system. This program is voluntary and is intended to simplify and accelerate the processing of applications for registration and reregistration while maintaining protection of public health and the environment. To be eligible for self-certification, a product must be formulated from registered source(s). | 402 |
| PR Notice 99-1; Import of Unregistered Pesticides Intended for Export | 1999-03-01 | PR Notice 99-1 | Pesticide Registration Notices by Year | This Pesticide Registration (PR) notice clarifies EPA's interpretation of the scope of the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) Section 17 (a)(1), as it relates to the import of unregistered pesticides, devices or active ingredients used in producing a pesticide when the importation is solely for the purpose of formulation or packaging for subsequent export. | 403 |
| PRN 2017-1 Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling | 2017-08-24 | PRN 2017-1 | PRN; Guidance; PRN 2017-1; 2017-1 | PRN 2017-1, Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling, revises and updates PRN 2001-5. PRN 2017-1 applies to all conventional, agricultural pesticides (i.e., herbicides, fungicides, bactericides, insecticides, and acaricides). | 430 |
| PRN 2018-1 Pesticides: Guidance for Registrants on the Determination of Minor Use | 2018-03-22 | PRN 2018-1 | PRN 2018-1; Pesticide Registration Notice; OPP; OCSPP | This PRN describes the revised approach to interpreting economic minor use based on the concept of the registration of a pesticide as an investment. | 432 |
| Assigning Values to Nondetected/ Nonquantified Pesticide Residues in Human Health Dietary Exposure Assessments | 2000-03-23 | EPA 705-G-2020-0007 | Dietary Exposure; Human Health Risk Assessment; Pesticide Residues; Non-Detected Residues; Limit of Quantification | OPP’s policy for assigning values for use in human health exposure and risk assessment to non-detected/non-quantified pesticide residues in food. In general, EPA recommends use of a value of ½ the analytical Limit of Detection (LOD), ½ the Limit of Quantitation (LOQ), the (full) Lower Limit of Method Validation (LLMV), or true zero for these non-detected residues. | 528 |
| Available EPA Information on Assessing Exposure to Pesticides in Food- A User's Guide | 2000-06-21 | EPA 705-G-2020-0008 | Dietary Exposure; Pesticide Residues in Food; Human Health Risk Assessment | Provides a simple overview of EPA's approach to estimating risk and exposure from pesticide residues in food, provides specifics on how to obtain or generate the data and/or information EPA uses in its assessments of exposure and risk from pesticides in food; and provides a list of helpful resources by topic area. | 529 |
| Choosing a Percentile of Acute Dietary Exposure as a Threshold of Regulatory Concern | 2000-03-16 | EPA 705-G-2020-0009 | Acute Dietary Exposure; Pesticide Residues in Food; Human Health Risk Assessment | EPA is responsible for regulating the nature and amount of pesticide residues in food under the Federal Food, Drug and Cosmetic Act (FFDCA). The Agency performs various types of risk assessments to evaluate the safety of pesticides in food, including analyses to determine the nature and the amounts of pesticides that people might be exposed to over a single day. This paper discusses how EPA generally applies the statutory safety standard to acute dietary risk assessments as to pesticide residues in foods. | 543 |
| Data for Refining Anticipated Residue Estimates Used in Acute Dietary Probabilistic Risk Assessments | 2000-06-15 | EPA 705-G-2020-0011 | Pesticide Data; Anticipated Residues; Dietary Exposure; Human Health Risk Assessment | The purpose of this document is to outline the types of data EPA's Office of Pesticide Programs can use to refine residue estimates for pesticides and explain when and how these data may be used. Specifically, this document is intended to provide additional guidance to registrants, other test sponsors, interested parties, and data reviewers on the extent and quality of pesticide residue and ancillary data needed to support the use of more refined “anticipated residues” in dietary exposure assessments. | 549 |
| Determination of the Appropriate FQPA Safety Factor(s) in Tolerance Assessment | 2002-02-28 | EPA 705-G-2020-0012 | Food Quality Protection Act; FQPA Safety Factor; Pesticide Exposure; Human Health Risk Assessment | This document describes how the Office of Pesticide Programs (OPP) determines the appropriate FQPA safety factor(s) when developing aggregate risk assessments and regulatory decisions for single active and "other" (i.e., inert) ingredients of pesticide products. The guidance is specifically addressed to OPP risk assessors but also serves as an important source of information for the public and the regulated community. | 553 |
| General Principles for Performing Aggregate Exposure and Risk Assessments | 2001-11-28 | EPA 705-G-2020-0014 | Human Health Risk Assessment; Aggregate exposure; Pesticides; Exposure Pathways | This document describes OPP's overall framework and the general principles for performing an aggregate exposure and risk assessment. Aggregate exposure and risk assessment involve the analysis of exposure to a single chemical by multiple pathways (e.g., food, drinking water, and residential uses) and routes (ingestion, dermal, and inhalation). | 564 |
| Guidance for Identifying Pesticide Chemicals and Other Substances That Have a Common Mechanism of Toxicity | 1999-01-29 | EPA 705-G-2020-0015 | Pesticide Chemicals; Common Mechanism of Toxicity; Cumulative Risk Assessment | The purpose of this document is to describe the approach that EPA will use for identifying and categorizing pesticides and other substances that cause common toxic effects from common mechanisms of toxicity. | 566 |
| Guidance on Cumulative Risk Assessment of Pesticide Chemicals That Have a Common Mechanism of Toxicity | 2002-01-14 | EPA 705-G-2020-0016 | Cumulative Risk Assessment; Pesticide Exposure; Common Mechanism of Toxicity | This document describes OPP's process for assembling and evaluating information that will constitute a cumulative risk assessment involving food, water, residential, and other nonoccupational exposures to multiple pesticides that share a common mechanism of toxicity. | 569 |
| The Use of Data on Cholinesterase Inhibition for Risk Assessments of Organophosphorous and Carbamate Pesticides | 2000-08-18 | EPA 705-G-2020-0045 | Human Health Risk Assessment; Cholinesterase inhibition; Organophosphate; Carbamate; Pesticides | This science policy document describes the approaches that the Office of Pesticide Programs (OPP) employs when evaluating data on cholinesterase inhibition and other cholinergic effects related to nervous system function that are the consequences of acetycholinesterase inhibition (i.e., physiological or behavioral 2007changes) in assessing the potential hazard following exposure to organophosphorous or carbamate pesticides that inhibit cholinesterase. | 682 |
| Residue Chemistry Test Guidelines: 860.1000 Supplement, Guidance on Constructing Maximum Reasonably Balanced Diets (MRBD) | 2008-06-30 | EPA 705-G-2020-0273 | Test Guideline; Residue Chemistry; Feedstuffs Revision | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 655 |
| Determining Toxicology Data Requirements | 2013-05-01 | EPA 705-G-2020-0594 | Pesticide Registration | Provide guidance on the weight of the evidence-based (WOE) determination of data needs for neurotoxicity, subchronic inhalation, subchronic, dermal and immunotoxicity studies and provide guidance on how to consider the data needs determination in risk assessment. Evaluation of waiver requests and development of registration review cases are typical situations in which OPP reviewers will make data need determinations. | 556 |
| Guidance for Thyroid Assays in Pregnant Animals, Fetuses and Postnatal Animals, and Adult Animals | 2005-10-24 | EPA 705-G-2020-1286 | Pesticide Registration | This study may be done in place of a rat DNT study for thyroid disrupting chemicals. This special study is intended to provide LOAEL or NOAEL to derive RfDs to be protective of thyroid development in pregnant women, fetuses or newborns. | 568 |
| (Quantitative) Structure Activity Relationship [(Q)SAR] Guidance Document (NAFTA) | 2012-11-01 | EPA 705-G-2020-1496 | Pesticide Registration | Guidance Document developed by the NAFTA Technical Working Group on the Quantitative Structure Activity Relationship. (Q)SAR represents a variety of techniques for predicting activities and properties of untested chemicals based on their structural similarity to chemicals with known activities and properties. | 522 |
| Pesticide Cumulative Risk Assessment: Framework for Screening Analysis | 2015-06-23 | EPA 705-G-2020-1561 | Pesticide Science; Assessing Pesticide Risks; Cumulative Risk Assessment; Screening Approach | This document provides guidance on how to screen groups of pesticides for cumulative evaluation using a two-step approach: beginning with the evaluation of available toxicological information and, if necessary, followed by a risk-based screening approach. This framework supplements the existing guidance documents for establishing common mechanism groups (CMGs) and conducting cumulative risk assessments (CRA). | 647 |
| Developmental Neurotoxicity Study Guidance (NAFTA) | 2016-12-01 | EPA 705-G-2020-1655 | Pesticide Science and Assessing Pesticide Risks | This guidance covers review and interpretation of DNT data and was developed collaboratively by EPA and Health Canada, with the goal of more consistent reviews of DNT data. | 559 |
| Thyroid Disrupting Pesticides: Use of Rat Thyroid Data and Application of Uncertainty Factors for RfD Derivation | 2005-11-01 | EPA 705-G-2020-2341 | Uncertainty Factors | The objective of this paper is to provide guidance on the use of toxicokinetic or dynamic information to replace the current standard default 10X uncertainty factors which are applied to address interspecies and interindividual (human) differences in the dose–response assessment for pesticides that have been shown to disrupt thyroid function in rats. | 683 |
| Preferred Vocabulary for Establishing Pesticide Tolerances | 2017-09-27 | EPA 705-G-2020-2344 | Pesticide Tolerances; Vocabulary | This document presents stakeholders who propose pesticide tolerances and regulatory staff charged with reviewing those proposals with the preferred vocabulary terms both for individual commodities and crop groups and subgroups | 648 |
| NAFTA Guidance Document on Data Requirements for Tolerances on Imported Commodities in the United States and Canada | 2005-12-01 | EPA 705-G-2020-2422 | data requirement; tolerance; MRL; NAFTA | Provides detailed guidance on data requirements that meet the North American Free Trade Agreement (NAFTA) standards for the establishment of pesticide import tolerances or maximum residue levels (MRL) in Canada and the United States. | 628 |
| Determining the Number of Field Trials Required to Register Seed-Treatment Uses | 2018-02-01 | EPA 705-G-2020-2425 | seed treatment | This page includes the guidance memo, decision trees and additional reference documents to help a manufacturer determine how many field trials are necessary to register seed-treatment uses. | 555 |
| Reduced Residue Chemistry Data Requirements for Seed-Treatment Uses | 2018-01-26 | EPA 705-G-2020-2426 | seed treatment | This document provides a tiered approach for determining if current crop-specific field trial data are required to support new seed treatment uses or if a reduction in number of field trials is appropriate. | 652 |
| Decision Tree for the Residue Data Requirements of Potato Seed-Piece (PSP) Treatments | 2018-01-26 | EPA 705-G-2020-2427 | seed treatment; PSP; decision tree | Diagrammatic representation of a decision Tree for the Residue Data Requirements of Potato Seed-Piece (PSP) Treatments. | 551 |
| Decision Tree for Seed Treatment (Excluding Potato Seed-Piece Treatment) | 2018-01-26 | EPA 705-G-2020-2428 | seed treatment; decision tree | Diagrammatic representation of a decision Tree for the Residue Data Requirements excluding Potato Seed-Piece (PSP) Treatments. | 550 |
| Classification of Seed Treatments as Food or Nonfood Uses | 1999-10-28 | EPA 705-G-2020-2429 | seed treatment; food; nonfood | Chem SAC determination of seed treatment uses as food versus nonfood based on the results of radiolabeled studies | 546 |
| Guidance for Reduced Residue Field Trial Requirements to Support Joint Projects Between Canada and the United States | 2018-08-23 | EPA 705-G-2020-2539 | Crop Field Trials | The purpose of this document is to communicate to industry and other interested parties, the revised crop trial requirements for trials that are conducted to support simultaneous domestic registration applications in both Canada and the United States. | 567 |
| Conclusions and Recommendations Regarding the Requirement for Inclusion of Adjuvants in Crop Field Trials | 2012-08-13 | EPA 705-G-2020-2643 | Pesticide Crop Field Trials | Conclusions and Recommendations Regarding the Requirement for Inclusion of Adjuvants in Crop Field Trials. | 548 |
| Developing a Tiered Framework for Extrapolation Modeling | 2017-03-14 | EPA 705-G-2020-2808 | Pesticide Registration | This is a web page describing how EPA extrapolates from animals to humans in its risk assessments | 557 |
| Proposed Approach to Efficiently Develop Physiologically Based Pharmacokinetic (PBPK) & Physiologically Based Pharmacokinetic-Pharmacodynamic (PBPK-PD) Models for Pesticides | 2017-03-14 | EPA 705-G-2020-2813 | Computational Modelling; PBPK; PBPK-PD Models | This document describes OPP's tiered framework for extrapolation modeling for animal >> human testing data. | 651 |
| Interim Science Policy: Use of Alternative Approaches for Skin Sensitization as a Replacement for Laboratory Animal Testing Draft for Public Comment | 2018-04-04 | EPA 705-G-2020-3111 | Alternative Approaches; Testing Methods; Skin Sensitization | This document describes the science supporting an interim science policy on the acceptance of alternative (in vitro, in silico, in chemico) approaches for identifying skin sensitization hazard. These approaches will be accepted in lieu of laboratory animal studies, most often the local lymph node assay (LLNA) in the mouse (OECD TG 429; OECD 2010a), and Buehler or maximization tests in the guinea pig (OECD TG 406, OECD 2010a). Although this document is a draft for public comment, given the substantial scientific evidence and international activities supporting NAMs for skin sensitization, OPP and OPPT will begin accepting these approaches immediately under the conditions described within. | 625 |
| E-Submission Chronic Toxicology Study Supplemental Files | 2002-07-01 | EPA 705-G-2020-3131 | Electronic Submission; Toxicology Data; Pesticide Registration | The formats and instructions in these documents are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the EPA's Office of Pesticide Programs for review in support of registration and reevaluation of pesticides. | 562 |
| Standard Format for Electronic Submission of Supplemental Data Files in Support of Chronic/Sub-Chronic Studies. | 2002-07-31 | EPA 705-G-2020-3132 | Electronic Submission; Toxicology Data; Pesticide Registration | The following formats and instructions are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. | 676 |
| Standard Format for Electronic Submission of Supplemental Data Files in Support of Developmental Neurotoxicity (DNT) Studies. | 2002-07-31 | EPA 705-G-2020-3133 | Electronic Submission; Toxicology Data; Pesticide Registration | The following formats and instructions are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. | 677 |
| Standard Format for Electronic Submission of Supplemental Data Files in Support of Prenatal Developmental Toxicity Data. | 2002-07-31 | EPA 705-G-2020-3134 | Electronic Submission; Toxicology Data; Pesticide Registration | registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. | 679 |
| Standard Format for Electronic Submission of Supplemental Data Files in Support of Multi-Generation Reproduction Studies. | 2002-07-31 | EPA 705-G-2020-3135 | Electronic Submission; Toxicology Data; Pesticide Registration | The following formats and instructions are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. | 678 |
| B.7 Residue Data | 2016-02-01 | EPA 705-G-2020-3318 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 531 |
| B.7.1 Plant Metabolism | 2016-02-01 | EPA 705-G-2020-3319 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 532 |
| B.7.2 Livestock Metabolism | 2016-02-01 | EPA 705-G-2020-3320 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 533 |
| B.5.2 Residue Analytical Methods | 2016-02-01 | EPA 705-G-2020-3321 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 530 |
| B.7.6.2 Freezer Storage Stability in Plants | 2016-02-01 | EPA 705-G-2020-3322 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 535 |
| B.7.8.3 Freezer Storage Stability in Livestock | 2016-02-01 | EPA 705-G-2020-3323 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 538 |
| B.7.8 Livestock Feeding | 2016-02-01 | EPA 705-G-2020-3324 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 537 |
| B.7.6 Crop Residue Trials | 2016-02-01 | EPA 705-G-2020-3325 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 534 |
| B.7.7 Processing | 2016-02-01 | EPA 705-G-2020-3326 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 536 |
| B.7.9 Confined Crop Rotation | 2016-02-01 | EPA 705-G-2020-3327 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 539 |
| B.7.9.2 Field Accumulation | 2016-02-01 | EPA 705-G-2020-3328 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 540 |
| 90-Day Oral Toxicity [dietary, gavage or drinking water] - [rodent species] | 2010-07-01 | EPA 705-G-2020-3335 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 526 |
| 90-Day Oral Toxicity [dietary, gavage or drinking water] - [non-rodent species] | 2010-07-01 | EPA 705-G-2020-3336 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 525 |
| 28-Day Dermal Toxicity - [species] | 2010-07-01 | EPA 705-G-2020-3337 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 523 |
| 90-Day Dermal Toxicity - [species] | 2010-07-01 | EPA 705-G-2020-3338 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 524 |
| Subchronic Inhalation Toxicity - [species] | 2010-07-01 | EPA 705-G-2020-3339 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 680 |
| Prenatal Developmental Toxicity Study - [rodent species] | 2010-07-01 | EPA 705-G-2020-3340 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 650 |
| Prenatal Developmental Toxicity Study - [non-rodent species] | 2010-07-01 | EPA 705-G-2020-3341 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 649 |
| Reproduction and Fertility Effects Study - [species] | 2010-07-01 | EPA 705-G-2020-3342 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 653 |
| Chronic Toxicity [dietary, gavage, drinking water, dermal or inhalation] - [rodent species] | 2010-07-01 | EPA 705-G-2020-3343 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 544 |
| Chronic Toxicity [feeding, water, dermal or inhalation] - [non-rodent species] | 2010-07-01 | EPA 705-G-2020-3344 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 545 |
| Supplementary Tumor Data Spreadsheet for Toxicology 870.4200 and 870.4300 | 2012-02-01 | EPA 705-G-2020-3345 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 681 |
| Guidance and Examples for Supplementary Tumor Data Spreadsheet for Toxicology 870.4200 and 870.4300 | 2012-02-01 | EPA 705-G-2020-3346 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 565 |
| Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - Mouse | 2010-07-01 | EPA 705-G-2020-3347 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 541 |
| Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - Rat | 2010-07-01 | EPA 705-G-2020-3348 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 542 |
| Combined Chronic Toxicity/Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - [species] | 2010-07-01 | EPA 705-G-2020-3349 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 547 |
| In Vitro Microbial Gene Mutation | 2010-07-01 | EPA 705-G-2020-3350 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 623 |
| In Vitro Mammalian Cells in Culture Gene Mutation Assay in [name cell type used] cells | 2010-07-01 | EPA 705-G-2020-3351 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 621 |
| In Vitro Mammalian Cytogenetics (specify assay) or In Vitro Sister Chromatid Exchange Assay in (name species/cell type) | 2010-07-01 | EPA 705-G-2020-3352 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 622 |
| In Vivo Mammalian Cytogenetics - Erythrocyte Micronucleus Assay in [name species] | 2010-07-01 | EPA 705-G-2020-3353 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 624 |
| Other Genotoxicity: Unscheduled DNA Synthesis in Primary Rat Hepatocytes / Mammalian Cell Culture | 2010-07-01 | EPA 705-G-2020-3354 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 646 |
| Neurotoxicity Screening Battery - Rat (Acute) | 2010-07-01 | EPA 705-G-2020-3355 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 629 |
| Neurotoxicity Screening Battery - Rat (Subchronic) | 2010-07-01 | EPA 705-G-2020-3356 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 630 |
| Developmental Neurotoxicity Study - Rat | 2010-07-01 | EPA 705-G-2020-3357 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 558 |
| Metabolism Study - Rat | 2010-07-01 | EPA 705-G-2020-3358 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 626 |
| Dermal Penetration | 2010-07-01 | EPA 705-G-2020-3359 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 552 |
| Immunotoxicity | 2010-07-01 | EPA 705-G-2020-3360 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 620 |
| Use Pattern/Exposure Scenarios | 2010-07-01 | EPA 705-G-2020-3361 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 684 |
| Residential Post Application Passive Dosimetry | 2010-07-01 | EPA 705-G-2020-3362 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 654 |
| Mixer/Loader/Applicator Passive Dosimetry | 2010-07-01 | EPA 705-G-2020-3363 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 627 |
| Agricultural Post Application Passive Dosimetry | 2010-07-01 | EPA 705-G-2020-3364 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 527 |
| Dislodgeable Turf Residues | 2010-07-01 | EPA 705-G-2020-3365 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 561 |
| Dislodgeable Foliar Residue | 2010-07-01 | EPA 705-G-2020-3366 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 560 |
| Determination of Transferable Residue on Indoor Treated Surfaces | 2010-07-01 | EPA 705-G-2020-3367 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 554 |
| Hand Press Residues | 2010-07-01 | EPA 705-G-2020-3368 | Study Profile Template | Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. | 570 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3050, Repeated Dose 28-day Oral Toxicity Study in Rodents | 2000-07-01 | EPA 712-C-00-366 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 610 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3550, Reproduction/Development Toxicity Screening Test | 2000-07-01 | EPA 712-C-00-367 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 616 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3650, Combined Repeated Dose Toxicity with the Reproduction/Development Toxicity Screening Test | 2000-07-01 | EPA 712-C-00-368 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 617 |
| Health Effects Test Guidelines: Health Effects Chemical-Specific Test Guidelines, 870.8355, Combined Chronic Toxicity/Carcinogenicity Testing of Respirable Fibrous Particles | 2001-07-01 | EPA 712-C-01-352 | Test Guidelines; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 599 |
| Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1000, Acute Toxicity Testing-Background | 2002-12-01 | EPA 712-C-02-189 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 571 |
| Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1100, Acute Oral Toxicity (AOT) | 2002-12-01 | EPA 712-C-02-190 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review | 572 |
| Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.2600, Skin Sensitization | 2003-03-01 | EPA 712-C-03-197 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 577 |
| Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7485, Metabolism and Pharmacokinetics | 1998-08-01 | EPA 712-C-95-244 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 607 |
| Residue Chemistry Test Guidelines: 860.1000, Background | 1996-08-01 | EPA 712-C-96-169 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 656 |
| Residue Chemistry Test Guidelines: 860.1100, Chemical Identity | 1996-08-01 | EPA 712-C-96-170 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 657 |
| Residue Chemistry Test Guidelines: 860.1200, Directions for Use | 1996-08-01 | EPA 712-C-96-171 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 658 |
| Residue Chemistry Test Guidelines: 860.1300, Nature of the Residue—Plants, Livestock | 1996-08-01 | EPA 712-C-96-172 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 659 |
| Residue Chemistry Test Guidelines: 860.1340, Residue Analytical Method | 1996-08-01 | EPA 712-C-96-174 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 660 |
| Residue Chemistry Test Guidelines: 860.1360, Multiresidue method | 1996-08-01 | EPA 712-C-96-176 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 661 |
| Residue Chemistry Test Guidelines: 860.1380, Storage Stability Data | 1996-08-01 | EPA 712-C-96-177 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 662 |
| Residue Chemistry Test Guidelines: 860.1400, Water, Fish, and Irrigated Crops | 1996-08-01 | EPA 712-C-96-178 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 663 |
| Residue Chemistry Test Guidelines: 860.1460, Food Handling | 1996-08-01 | EPA 712-C-96-181 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 664 |
| Residue Chemistry Test Guidelines: 860.1480, Meat/Milk/Poultry/Eggs | 1996-08-01 | EPA 712-C-96-182 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 665 |
| Residue Chemistry Test Guidelines: 860.1500, Crop Field Trials | 1996-08-01 | EPA 712-C-96-183 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 666 |
| Residue Chemistry Test Guidelines: 860.1520, Processed Food/Feed | 1996-08-01 | EPA 712-C-96-184 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 667 |
| Residue Chemistry Test Guidelines: 860.1550, Proposed Tolerances | 1996-08-01 | EPA 712-C-96-186 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 668 |
| Residue Chemistry Test Guidelines: 860.1560, Reasonable Grounds in Support of the Petition | 1996-08-01 | EPA 712-C-96-187 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 669 |
| Residue Chemistry Test Guidelines: 860.1850, Confined Accumulation in Rotational Crops | 1996-08-01 | EPA 712-C-96-188 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 671 |
| Residue Chemistry Test Guidelines: 860.1900, Field Accumulation in Rotational Crops | 1996-08-01 | EPA 712-C-96-189 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 672 |
| Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1200, Dermal Exposure—Indoor | 1996-02-01 | EPA 712-C-96-209 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 633 |
| Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1400, Inhalation Exposure—Indoor | 1996-02-01 | EPA 712-C-96-213 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 635 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2200, Soil Residue Dissipation | 1996-02-01 | EPA 712-C-96-243 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 640 |
| Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1000, Background for Application Exposure Monitoring Test Guidelines | 1996-02-01 | EPA 712-C-96-261 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 631 |
| Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1100, Dermal Exposure—Outdoor | 1996-02-01 | EPA 712-C-96-262 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 632 |
| Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1300, Inhalation Exposure—Outdoor | 1996-02-01 | EPA 712-C-96-263 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 634 |
| Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1500, Biological Monitoring | 1996-02-01 | EPA 712-C-96-264 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 636 |
| Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1600, Application Exposure Monitoring Data Reporting | 1996-02-01 | EPA 712-C-96-265 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 637 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2000, Background for Postapplication Exposure Monitoring Test Guidelines | 1996-02-01 | EPA 712-C-96-266 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 638 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2100, Foliar Dislodgeable Residue Dissipation | 1996-02-01 | EPA 712-C-96-267 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 639 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2400, Dermal Exposure | 1996-02-01 | EPA 712-C-96-269 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 641 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2500, Inhalation Exposure | 1996-02-01 | EPA 712-C-96-270 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 642 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2600, Biological Monitoring | 1996-02-01 | EPA 712-C-96-271 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 643 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2900, Data Reporting and Calculations | 1996-02-01 | EPA 712-C-96-272 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 645 |
| Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2800, Descriptions of Human Activity | 1996-02-01 | EPA 712-C-96-283 | Test Guideline; Occupational and Residential Exposure | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 644 |
| Spray Drift Test Guidelines: , 840.1100, Spray Droplet Size Spectrum | 1998-03-01 | EPA 712-C-98-055 | Test Guidelines; Spray Drift | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 674 |
| Spray Drift Test Guidelines: , 840.1200, Spray Drift Field Deposition | 1998-03-01 | EPA 712-C-98-112 | Test Guideline; Spray Drift | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 675 |
| Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1200, Acute Dermal Toxicity | 1998-08-01 | EPA 712-C-98-192 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 573 |
| Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1300, Acute Inhalation Toxicity | 1998-08-01 | EPA 712-C-98-193 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 574 |
| Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.2400, Acute Eye Irritation | 1998-08-01 | EPA 712-C-98-195 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 575 |
| Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.2500, Acute Dermal Irritation | 1998-08-01 | EPA 712-C-98-196 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 576 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3100, 90-Day Oral Toxicity in Rodents | 1998-08-01 | EPA 712-C-98-199 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 611 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3150, 90-Day Oral Toxicity in Nonrodents | 1998-08-01 | EPA 712-C-98-200 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 612 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3200, 21/28-Day Dermal Toxicity | 1998-08-01 | EPA 712-C-98-201 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 613 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3250, 90-Day Dermal Toxicity | 1998-08-01 | EPA 712-C-98-202 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 614 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3465, 90-Day Inhalation Toxicity | 1998-08-01 | EPA 712-C-98-204 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 615 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3700, Prenatal Developmental Toxicity Study | 1998-08-01 | EPA 712-C-98-207 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 618 |
| Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3800, Reproduction and Fertility Effects | 1998-08-01 | EPA 712-C-98-208 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 619 |
| Health Effects Test Guidelines: Chronic Toxicity Test Guidelines, 870.4100, Chronic Toxicity | 1998-08-01 | EPA 712-C-98-210 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 578 |
| Health Effects Test Guidelines: Chronic Toxicity Test Guidelines, 870.4200, Carcinogenicity | 1998-08-01 | EPA 712-C-98-211 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 579 |
| Health Effects Test Guidelines: Chronic Toxicity Test Guidelines, 870.4300, Combined Chronic Toxicity/Carcinogenicity | 1998-08-01 | EPA 712-C-98-212 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 580 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5140, Gene Mutation in Aspergillus nidulans | 1998-08-01 | EPA 712-C-98-215 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 582 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5195, Mouse Biochemical Specific Locus Test | 1998-08-01 | EPA 712-C-98-216 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 583 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5200, Mouse Visible Specific Locus Test | 1998-08-01 | EPA 712-C-98-217 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 584 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5250, Gene Mutation in Neurospora crassa | 1998-08-01 | EPA 712-C-98-218 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 585 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5275, Sex-linked Recessive Lethal Test in Drosophila melanogaster | 1998-08-01 | EPA 712-C-98-220 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 586 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5300, In vitro Mammalian Cell Gene Mutation Test | 1998-08-01 | EPA 712-C-98-221 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 587 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5375, In Vitro Mammalian Chromosome Aberration Test | 1998-08-01 | EPA 712-C-98-223 | Test Guidelines; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 588 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5380, Mammalian Spermatogonial Chromosomal Aberration Test | 1998-08-01 | EPA 712-C-98-224 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 589 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5385, Mammalian Bone Marrow Chromosomal Aberration Test | 1998-08-01 | EPA 712-C-98-225 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 590 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5395, Mammalian Erythrocyte Micronucleus Test | 1998-08-01 | EPA 712-C-98-226 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 591 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5450, Rodent Dominant Lethal Assay | 1998-08-01 | EPA 712-C-98-227 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 592 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5460, Rodent Heritable Translocation Assays | 1998-08-01 | EPA 712-C-98-228 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 593 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5500, Bacterial DNA Damage or Repair Tests | 1998-08-01 | EPA 712-C-98-229 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 594 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5550, Unscheduled DNA Synthesis in Mammalian Cells in Culture | 1998-08-01 | EPA 712-C-98-230 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 595 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5575, Mitotic Gene Conversion in Saccharomyces cerevisiae | 1998-08-01 | EPA 712-C-98-232 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 596 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5900, In Vitro Sister Chromatid Exchange Assay | 1998-08-01 | EPA 712-C-98-234 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 597 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5915, In Vitro Sister Chromatid Exchange Assay | 1998-08-01 | EPA 712-C-98-235 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 598 |
| Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6100, Acute and 28-day Delayed Neurotoxicity of Organophosphorus Substances | 1998-08-01 | EPA 712-C-98-237 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 600 |
| Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6200, Neurotoxicity Screening Battery | 1998-08-01 | EPA 712-C-98-238 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 601 |
| Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6300, Developmental Neurotoxicity Study | 1998-08-01 | EPA 712-C-98-239 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 602 |
| Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6500, Schedule-Controlled Operant Behavior | 1998-08-01 | EPA 712-C-98-240 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 603 |
| Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6850, Peripheral Nerve Function | 1998-08-01 | EPA 712-C-98-241 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 604 |
| Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6855, Neurophysiology: Sensory Evoked Potentials | 1998-08-01 | EPA 712-C-98-242 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 605 |
| Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5100, Bacterial Reverse Mutation Test | 1998-08-01 | EPA 712-C-98-247 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 581 |
| Spray Drift Test Guidelines: , 840.1000, Background for Pesticide Aerial Drift Evaluation | 1998-03-01 | EPA 712-C-98-319 | Test Guideline; Spray Drift | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 673 |
| Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7200, Companion Animal Safety | 1998-08-01 | EPA 712-C-98-349 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 606 |
| Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7600, Dermal Penetration | 1998-08-01 | EPA 712-C-98-350 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 608 |
| Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3160, Biodegradability in Sea Water | 1998-01-01 | EPA 712-C-98-351 | Test Guideline; Fate, Transport and Transformation | The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 563 |
| Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7800, Immunotoxicity | 1998-08-01 | EPA 712-C-98-351 | Test Guideline; Health Effects | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 609 |
| Residue Chemistry Test Guidelines: 860.1650, Submittal of Analytical Reference Standards | 2008-11-01 | EPA 712-F-08-001 | Test Guideline; Residue Chemistry | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 670 |
| Small Business Certification Examples | 2018-01-01 | EPA 705-G-2020-0598 | PRIA Fees | An example of a certification for small business. | 699 |
| Data Requirements Checklists for PRIA Fee Categories | 2014-03-10 | EPA 705-G-2020-0601 | PRIA Fees | Data requirements checklists for PRIA fee categories | 687 |
| Paying PRIA Application Fees | 2018-01-01 | EPA 705-G-2020-0602 | PRIA Fees | Describes how to the Agency review of a fee payment, how to submit payment for PRIA application, different methods of payment. | 697 |
| Appeals of Fee and Waiver Decisions | 2019-01-01 | EPA 705-G-2020-0603 | PRIA Fees | Describes how an applicant can appeal a fee or waiver determination by the EPA. | 685 |
| Checklists for 45/90 Preliminary Technical Screen | 2018-01-01 | EPA 705-G-2020-0605 | PRIA Fees | Applicant may use checklists to ensure that their application is complete and ready for in-depth review, as required by FIFRA. Applicants may submit the checklists with their application. | 686 |
| Fee Reduction Tables | 2023-03-02 | EPA 705-G-2020-0607 | PRIA Fees | Under PRIA, refunds for a portion of the registration service fee are provided following the withdrawal of a PRIA covered application and at the request of an applicant. These tables provide the information for each registering division. | 691 |
| Interpretations of PRIA 3 Fee Categories | 2015-07-17 | EPA 705-G-2020-0608 | PRIA Fees | This document includes the expanded information about PRIA fee categories. | 692 |
| Templates and Instructions for PRIA Fee Payments | 2016-01-01 | EPA 705-G-2020-1284 | PRIA Fees | The documents on this page provide templates and instructions for bank transfer and wire payments of PRIA fees. | 702 |
| Exemptions for Federal and State Governments under PRIA | 2016-01-01 | EPA 705-G-2020-2512 | PRIA | Information on how an agency of the federal government or a state government shall be exempt from covered registration service fees. | 689 |
| PRIA Fee Waivers for Small Businesses | 2014-03-04 | EPA 705-G-2020-2513 | PRIA | Information on PRIA fee waivers for small businesses | 698 |
| Overview of PRIA Fee Reduction and Refund Formula | 2019-01-01 | EPA 705-G-2020-2515 | PRIA | Information on how the Agency calculates registration service fee reductions and refunds under PRIA. | 696 |
| Factors for IR-4 Public Interest Finding | 2019-01-01 | EPA 705-G-2020-2516 | PRIA | Information on the factors the Agency considers to make an IR-4 public interest finding for a PRIA registration service fee exemption | 690 |
| Interpretations of PRIA 4 Fee Categories | 2019-01-01 | EPA 705-G-2020-2649 | PRIA Fees | These 19 documents provides interpretations associated with each PRIA 4 fee category. | 693 |
| Office of Pesticide Program Electronic Label (OPPEL) Pilot | 2018-01-01 | EPA 705-G-2020-3596 | OPPEL | In an effort to make pesticide label information easier to find and the approval of pesticide labels more efficient, EPA is working with pesticide registrants to pilot an electronic label system. As part of the OPPEL pilot, nine pesticide registrants will be developing and submitting pesticide labels to EPA through a fully electronic system, instead of as paper or PDF files. | 694 |
| Structured Product Labeling (SPL) User Guide (unabridged) | 2018-02-05 | EPA 705-G-2020-3597 | OPPEL | The purpose of this document is to provide instructions on how to use the OPPEL Product Label (SPL) Builder. This document provides guidance on how to properly prepare a Product Label and/or Use Index document for submission to EPA. | 701 |
| EPA CDX SmartLabel Builder User Guide Version 2 | 2018-04-18 | EPA 705-G-2020-3598 | OPPEL | This document provides information on EPA's OPPEL Builder is a Structured Product Label (SPL) document builder, located within the EPA’s Central Data Exchange (CDX). The SPL Builder is the Agency’s publicly offered tool to build, validate, and submit structured xml files to the EPA for review and registration. | 688 |
| Structured Product Labeling (SPL) Draft Implementation Guide with Validation Procedures and User Guide | 2018-01-01 | EPA 705-G-2020-3599 | FIFRA; Labeling | This document provides an introduction to the OPPEL Model, as well as guidance on how to extract pesticide information into the Structured Product Label (SPL) model for submission to EPA. | 700 |
| OPPEL Pilot Document Guides, including Vocabulary Guide Version 3 | 2018-09-29 | EPA 705-G-2020-3600 | OPPEL | These documents are being used to pilot the OPPEL process, in particular the model for constructing an OPPEL label. | 695 |
| Assembly of Electronic Packages and Discs | 2013-05-03 | EPA 705-G-2020-0479 | Pesticide Registration | Methods for assembling electronic packages and creating submission discs | 704 |
| Study Formatting and Supplemental Information | 2019-09-17 | EPA 705-G-2020-0481 | Pesticide Registration; Study Formatting; Supplemental Information | Information and guidance on e-submission study formatting and supplemental files and review aids. | 722 |
| E-submission Resource Documents for Assembly of Electronic Packages and Discs | 2018-03-30 | EPA 705-G-2020-0487 | Pesticide Registration; E-submission; Electronic Packages | Learn more about submitting pesticide applications via the Pesticide Submission Portal. | 711 |
| Full Specifications for Text PDF Label Submissions | 2008-01-17 | EPA 705-G-2020-0492 | Pesticide Registration; Specifications Label Submissions | The following guidance is provided for creating and submitting product labels in electronic format to EPA. Submission of electronic labels to EPA is voluntary, but if done then two specifications are mandatory. | 714 |
| E-Submission Guidance Updates | 2019-02-15 | EPA 705-G-2020-0493 | Pesticide Registration; E-submission Guidance; Dossier-Formatted | E-submission guidance updates for all e-submissions and Dossier formatted submissions. | 710 |
| Critical PDF Label Specifications for Electronic Submission | 2017-02-23 | EPA 705-G-2020-0498 | Pesticide Registration; Electronic Submission Label Specifications | Guidance information about electronic submission for critical PDF label specifications. | 707 |
| Frequent Questions about Electronic Submission of Labels | 2017-04-14 | EPA 705-G-2020-0499 | Pesticide Registration; Electronic Label Submission FAQs | Find information to help you with e-submission of labels. | 713 |
| Creating a PDF Version of Study Reports - General Specifications | 2008-06-25 | EPA 705-G-2020-0563 | Pesticide Registration | This document lists software, layout, and other specifications for creating PDF versions of study reports for electronic submission for pesticide registration. | 706 |
| How to Search for Information about Pesticide Ingredients and Labels | 2014-01-06 | EPA 705-G-2020-0574 | Ingredients Used in Pesticide Products | How to use the databases Pesticide Chemical Search, Pesticide Product Label System (PPLS), and InertFinder to find information such as Chemical Abstract Service (CAS) numbers, active and inert ingredients, and regulatory actions. | 715 |
| 2020 Annual Pesticide Registration Maintenance Fees | 2019-11-26 | EPA 705-G-2020-1098 | Pesticide Registration | All section 3 and section 24(c) registrations are subject to an annual maintenance fee described in FIFRA Section 4(i)(5). The amount of this fee varies from year to year depending on the authorizing legislation. Affected applicants will be contacted by mail with instructions for submitting the fee. The deadline for responding to the maintenance fee notification is Wednesday, January 15, 2020. The fee per product will vary from year to year as the fee is dependent upon the projected number of products for which registrants will pay this fee. The fee for 2020 is $4,000. Please note that checks, bank drafts and money orders are no longer an acceptable form of payment. | 703 |
| Pesticide Submissions Portal (PSP) Frequently Asked Questions | 2015-09-18 | EPA 705-G-2020-1448 | Pesticide Registration | Pesticide Submissions Portal (PSP) Frequently Asked Questions | 720 |
| Disclosure of Reviews of Pesticide Test Data | 1985-11-27 | EPA 705-G-2020-1484 | Pesticide Registration | This document describes a class determination that certain EPA-prepared reviews of data submitted under the Federal insecticide, Fungicide, and Rodenticide Act are not entitled to confidential treatment. | 709 |
| Data Compensation Documents | 1984-08-01 | EPA 705-G-2020-1494 | Pesticide Registration | EPA does not have specific forms to use related to data compensation for inert ingredients. These documents will help the registrant with the process. | 708 |
| Pesticide Product Label System (PPLS) Application Program Interface (API) | 2016-06-20 | EPA 705-G-2020-1564 | Pesticide Labels | Pesticide Product Label System (PPLS) provides a single point of access to U.S. EPA environmental data contained in the U.S. EPA databases. | 719 |
| Voluntary Incident Reporting Forms and Instructions | 1998-08-04 | EPA 705-G-2020-1747 | Reporting Pesticide Incidents | Reporting forms that can be used by Registrants to report 6(a)(2) related incidents to the EPA. | 724 |
| Electronic Submissions of Pesticide Applications | 2019-08-19 | EPA 705-G-2020-2411 | electronic submission; portal; PSP; application materials | General Information about Electronic Submission of Pesticide Applications, application materials required and tools for developing an electronic submission. | 712 |
| National List of Active EPA-Registered Foreign and Domestic Pesticide and/or Device-Producing Establishments | 2019-10-21 | EPA 705-G-2020-2456 | Pesticide Registration; establishment | This website contains guidance on updating establishments and includes a CSV file lists the most current non-Confidential Business Information (CBI) of active EPA-registered foreign and domestic pesticide-producing and device-producing establishments based on data from the Section Seven Tracking System (SSTS). | 716 |
| Pesticide Submissions Portal (PSP) User Guide | 2018-03-28 | EPA 705-G-2020-2822 | Pesticide Registration, CDX, PSP, pesticide submissions portal | The purpose of this PDF document is to provide instructions on how to use the PSP application. This document provides guidance on how to properly prepare a package for submission to EPA. | 721 |
| CDX Pesticide Submissions Portal (PSP) Registration User Guide | 2016-02-12 | EPA 705-G-2020-2823 | Pesticide Registration, CDX, PSP, pesticide submissions portal; central data exchange | The purpose of this PDF document is to walk through the registration and user profile management processes in CDX, specifically for Pesticide Submission Portal (PSP) workflow submissions. | 705 |
| Office of Pesticide Programs eDossier Builder User Guide | 2015-08-27 | EPA 705-G-2020-2824 | eSubmission; XML; eDossier; eDossier Builder | The eDossier Builder system, developed by the Environmental Protection Agency (EPA) Office of Pesticide Programs (OPP), allows registrants to create packages for electronic submission in a user-friendly manner and presents packages to EPA systems in a specified format. | 717 |
| Office of Pesticide Programs eSubmission XML Guidance Document | 2015-08-26 | EPA 705-G-2020-2825 | Pesticide Registration, eSubmission, XML | The purpose of this PDF document is to provide registrants instructions for constructing an XML file for inclusion in an electronic submission package and submitting the documents to the Environmental Protection Agency (EPA) Office of Pesticide Programs (OPP) electronically on CD/DVD. | 718 |
| Submitting EPA Form 3540-16 Through the SSTS CDX Application | 2016-10-12 | EPA 705-G-2020-2836 | 3540-16 | PDF for Submitting EPA Form 3540-16 Through the SSTS CDX Application | 723 |
| Tarp Testing Guidance | 2019-06-06 | EPA 705-G-2020-0561 | Soil Fumigants | Since the reactivity, stability, and other chemical properties are different for each soil fumigant pesticide, the permeability of each fumigant through a film will be different. Certain tarps that qualify for buffer zone reduction credits are listed. | 730 |
| Soil Fumigant Buffer Zone Calculator | 2018-07-01 | EPA 705-G-2020-3052 | Soil Fumigants | Buffer zone calculator tool for applicators, growers, and enforcement personnel applying/monitoring soil fumigant applications. | 728 |
| Methyl Bromide Commodity Fumigation Buffer Zone Lookup Tables | 2017-03-13 | EPA 705-G-2020-3054 | Fumigants | The labels of the products listed require that all applications must have a specified buffer zone around treatment and aeration areas. Buffer zone distances must be determined according to the tables and instructions listed. The applicable buffer zone is part of the directions for use of these products. | 726 |
| Enhancing Stakeholder Input in the Pesticide Registration Review and ESA Consultation Processes and Development of Economically and Technologically Feasible Reasonable and Prudent Alternatives | 2013-03-19 | EPA 705-G-2020-3071 | Endangered Species; Pesticides | This document, which was developed jointly by the EPA, the U.S. Department of Agriculture (USDA), the National Marine Fisheries Service (NMFS) in the U.S. Department of Commerce and the Fish and Wildlife Service (USFWS) in the U.S. Department of Interior, provides guidance to staff and managers participating in the associated processes. | 725 |
| Opportunities to Participate in Pesticide Reevaluation | 2019-05-02 | EPA 705-G-2020-3075 | Pesticides | Web page providing information about the public participation process during registration review. | 727 |
| Soil Fumigant Toolbox | 2018-07-10 | EPA 705-G-2020-3610 | Soil Fumigants | This website provides soil fumigant information on training, fumigant management plans, buffer zones, and other safety measures to ensure protections for agricultural workers and bystanders. | 729 |
| Pesticide Registration | 2019-12-19 | EPA 705-G-2020-0411 | Pesticide Registration | This site provides resources for an individual or company wanting to register a pesticide active ingredient or pesticide product in the United States. Features: a manual (blue book), other guidance, and coordinated lists of requirements by pesticide type. | 811 |
| Pesticide Registration Manual | 2017-04-20 | EPA 705-G-2020-0412 | Pesticide Registration Manual; | Describes the pesticide registration process for companies and individuals wanting to register their pesticide product. | 812 |
| Conventional Pesticide Registration | 2017-03-20 | EPA 705-G-2020-0413 | Pesticide Registration; Conventional | Conventional pesticides are all active ingredients other than biological pesticides and antimicrobial pesticides. Learn about the requirements and process for registering a conventional pesticide. | 742 |
| Study Profile Templates | 2017-04-25 | EPA 705-G-2020-0432 | Pesticide Registration; Study Profile Templates | Listing of study profile templates and brief description about each to include downloadable file in Word and/or PDF formats. | 947 |
| Conventional Reduced Risk Pesticide Program | 2019-09-14 | EPA 705-G-2020-0434 | Pesticide Registration; Reduced Risk | Find out about the Conventional Reduced Risk Pesticide Program, which expedites the review and regulatory decision-making process of conventional pesticides that pose less risk to human health and the environment than existing conventional alternatives. | 743 |
| Inert Ingredients Overview and Guidance | 2020-01-30 | EPA 705-G-2020-0444 | Pesticide Registration; FIFRA; Pesticides; Antimicrobial; | This Web page provides information on inert ingredients approved for use in pesticide products and the guidance documents that are available to assist in obtaining approval for a new inert ingredient. | 771 |
| Registration Requirements and Guidance | 2017-04-18 | EPA 705-G-2020-0467 | Pesticide Registration; Requirements; Guidance; Forms; Data Requirements | This page lists the categories of requirements that all applicants for all categories of pesticides must complete to help you navigate the process. | 909 |
| Label Review Manual | 2019-05-09 | EPA 705-G-2020-0470 | Pesticide Registration; Label Review Manual | Table of Contents for Label Review Manual | 775 |
| Pesticide Registration Manual: Introduction | 2018-04-02 | EPA 705-G-2020-0483 | Pesticide Registration Manual | This manual is intended as a resource for companies and individuals who wish to have their pesticide products registered by EPA. This introduction gives an overview of the contents of the manual. | 844 |
| Pesticide Registration Manual: Chapter 1 - Overview of Requirements for Pesticide Registration and Registrant Obligations | 2019-11-21 | EPA 705-G-2020-0484 | Pesticide Registration Manual; Overview of Requirements; Registrant Obligations | This chapter provides an overview of the federal laws under the authority of which EPA oversees pesticide use in the U.S. | 818 |
| Pesticide Registration Manual: Chapter 2 - Registering a Pesticide Product | 2017-12-20 | EPA 705-G-2020-0491 | Pesticide Registration Manual; Guidance Registering Pesticide Product; Examples | This chapter discusses what information is required to be submitted to EPA when applying for a pesticide product registration and the process for reviewing the applications. | 829 |
| Suggested Format for Acute Toxicity Studies | 2008-06-01 | EPA 705-G-2020-0503 | Pesticide Registration; Format Acute Toxicity Studies | This document suggests the format for final reports on pesticide studies (right column of the tables in the document) and provides instructions for the creation of PDF Version 1.3 electronic submission documents (left column of the tables). | 948 |
| Pesticide Registration Manual: Chapter 5 - Registration Fees | 2018-04-02 | EPA 705-G-2020-0504 | Pesticide Registration Manual; Registration Fees | Information about pesticide registration fees according to the Pesticide Registration Improvement Extension Act (PRIA 3) | 832 |
| Pesticide Registration Manual: Chapter 6 - Amending a Registered Pesticide Product | 2017-08-30 | EPA 705-G-2020-0505 | Pesticide Registration Manual; Amending Product Registration | This chapter covers all aspects of amending a registered product including label changes, formulation changes, associated data requirements, and the forms that need to be submitted. | 833 |
| Pesticide Registration Manual: Chapter 7 - Notifications and Minor Formulation Amendments | 2017-08-02 | EPA 705-G-2020-0506 | Pesticide Registration Manual; Notifications; Minor Formulation Amendments | This chapter provides information about preparing and submitting a notification for a pesticide product | 834 |
| Pesticide Registration Manual: Chapter 8 - Inert Ingredients | 2017-05-24 | EPA 705-G-2020-0507 | Pesticide Registration Manual; Inert Ingredients | This chapter describes how EPA reviews inert ingredients as part of the pesticide product review process. | 835 |
| Pesticide Registration Manual: Chapter 9 - Supplemental Distribution of a Registered Pesticide | 2017-07-13 | EPA 705-G-2020-0508 | Pesticide Registration Manual; Supplemental Distribution | This chapter provides information about the supplemental distribution of a registered pesticide or product. | 837 |
| Pesticide Registration Manual: Chapter 10 - Data Compensation Requirements | 2017-05-24 | EPA 705-G-2020-0509 | Pesticide Registration Manual; Data Compensation; Requirements | This chapter provides information about data compensation requirements, procedures, and obligations when submitting an application for registration, amended registration, reregistration or registration review. | 819 |
| Pesticide Registration Manual: Chapter 11 - Tolerance Petitions | 2018-04-02 | EPA 705-G-2020-0510 | Pesticide Registration Manual; Tolerance Petitions | This Chapter provides information on definitions, interpretative regulations and procedures for filing a petition for establishment of a tolerance or an exemption from the requirement of a tolerance. | 820 |
| Pesticide Registration Manual: Chapter 12 - Applying for an Experimental Use Permit | 2017-05-23 | EPA 705-G-2020-0511 | Pesticide Registration Manual; Experimental Use Permit | This chapter of the pesticide registration manual describes the all requirements for Experimental Use Permits (EUP), and includes how to apply for an EUP, labeling requirements, application format, and data reporting requirements. | 821 |
| Pesticide Registration Manual: Chapter 13 - Devices | 2017-05-24 | EPA 705-G-2020-0512 | Pesticide Registration Manual; Devices | This chapter describes how EPA regulates pesticidal devices. | 822 |
| Bridging or Waiving Data Requirements | 2019-09-17 | EPA 705-G-2020-0513 | Pesticide Registration; Bridging Data Requirements | Pesticide registrants can request a waiver of data requirements or seek to bridge data from one data set to another. The documents below explain our approach to data waivers. | 739 |
| Pesticide Registration Manual: Chapter 14 - How to Obtain an EPA Company or Establishment Number or Change Address or Contact Information | 2019-10-03 | EPA 705-G-2020-0514 | Pesticide Registration; Manual; EPA Company or Establishment Number | This chapter provides information on how to get an establishment number for pesticide registration applicants | 823 |
| Pesticide Registration Manual: Chapter 15 - Submitting Data and Confidential Business Information | 2017-05-24 | EPA 705-G-2020-0515 | Pesticide Registration Manual; Submitting; Confidential Business Information | This chapter includes information on how to submit data as well as special considerations concerning what data and information can be considered to be confidential business information. | 824 |
| Pesticide Registration Manual: Chapter 16 - Transfer of Product Registrations and Data Rights | 2020-01-15 | EPA 705-G-2020-0518 | Pesticide Registration Manual; Transfer of Products; Data Rights | This chapter discusses specific information to be submitted to EPA for the transfer of product registration and/or data rights from one person or company to another. | 825 |
| Pesticide Registration Manual: Chapter 17 - State Regulatory Authority | 2019-07-29 | EPA 705-G-2020-0519 | Pesticide Registration Manual; State Authority | FIFRA authorizes states to issue Experimental Use Permits, Special Local Needs registrations, and to apply for Emergency Exemptions under specific conditions. This chapter provides detailed information relevant to state actions under FIFRA. | 826 |
| Pesticide Registration Manual: Chapter 18 - Other Federal or State Agency Requirements | 2019-07-29 | EPA 705-G-2020-0520 | Pesticide Registration Manual; Other Federal Requirements; State Agency Requirements | This chapter provides information that a pesticide registrant may need know in order to meet other federal, state, or local requirements after the registrant has obtained a federal registration. | 827 |
| Pesticide Registration Manual: Chapter 19 - How to Obtain Publications | 2018-12-18 | EPA 705-G-2020-0521 | Pesticide Registration Manual; Obtaining Publications | This chapter provides information on how and where to obtain publications. | 828 |
| Pesticide Registration Manual: Chapter 20 - Forms and How to Obtain Them | 2017-02-28 | EPA 705-G-2020-0522 | Pesticide Registration Manual; Forms | This chapter provides listings of the forms that are required when applying for a pesticide product, experimental use permit, and distributor registrations. | 830 |
| Pesticide Registration Manual: Chapter 21 - Directions for Submitting Applications and Contacting EPA | 2018-04-02 | EPA 705-G-2020-0523 | Pesticide Registration Manual; Submitting Applications | This chapter provides directions for submitting application information to the EPA pesticide program. | 831 |
| Pesticide Registration Manual: Appendix B - Examples of Registrant Documents | 2017-08-31 | EPA 705-G-2020-0524 | Pesticide Registration Manual | Examples of Registrant Documents | 814 |
| Pesticide Registration Manual: Appendix C - Pesticide Forms Overview Table | 2016-11-05 | EPA 705-G-2020-0525 | Pesticide Registration Manual; Pesticide Forms | This chapter provides listings of the forms that are required when applying for a pesticide product, experimental use permit, and distributor registrations | 815 |
| Pesticide Registration Manual: Appendix A - Guidance Documents | 2017-03-13 | EPA 705-G-2020-0526 | Pesticide Registration Manual | Find links to EPA guidance documents supporting the pesticide registration process. | 813 |
| Pesticide Registration Manual: Appendix D - Examples of Completed Forms | 2020-01-07 | EPA 705-G-2020-0529 | Pesticide Registration Manual; Examples | View examples of completed pesticide registration forms. | 816 |
| Pesticide Registration Manual: Registrant Summary of Pesticide Petitions for EPA's Notice of Filing | 2011-10-01 | EPA 705-G-2020-0530 | Pesticide Registration Manual; Electronic Submission | Provides a company with information to electronically prepare and submit a pesticide tolerance petition to EPA. | 847 |
| Pesticide Registration Manual: Blank Forms | 2020-01-07 | EPA 705-G-2020-0542 | Pesticide Registration Manual; Forms | These forms are to be used by applicants for pesticide registration. | 817 |
| Pesticide Registration Manual: Confidential Statement of Formula Documents | 2012-09-11 | EPA 705-G-2020-0545 | Pesticide Registration; Confidential Statement of Formula; Attachment | These documents will help you complete the confidential statement of formula for pesticides registrations. | 838 |
| Pesticide Registration Manual: Product Chemistry | 2017-02-21 | EPA 705-G-2020-0546 | Pesticide Registration; Product Chemistry | These documents will help you avoid common mistakes in completing the product chemistry aspect of the pesticide registration form. | 846 |
| Pesticide Registration Manual: How to Obtain a Company Number and Register an Official Address | 2019-03-19 | EPA 705-G-2020-0547 | Pesticide Registration; Company Number; Company Address | Registrants must obtain a company number before registering their first product with the Agency. Registrants or others who plan to “produce” pesticides or devices must obtain the company number first, then submit EPA Form 3540-8. Find out how to do this. | 842 |
| Pesticide Registration Manual: List of Data Submitters Sent Offer to Pay Letters | 2016-11-05 | EPA 705-G-2020-0548 | Pesticide Registration Manual; Data Submitter's List | Sample format for providing the list of data submitters to whom you sent offer to pay letters. | 845 |
| Pesticide Registration Manual: Example Transmittal Document | 2016-11-05 | EPA 705-G-2020-0549 | Pesticide Registration Manual; Transmittal Document | This example can be used in setting up a transmittal document for a pesticide registration package. | 841 |
| Pesticide Registration Manual: Title Page For a Newly Submitted Study | 2017-07-03 | EPA 705-G-2020-0550 | Pesticide Registration Manual; Title Page | Certain information should be included on the title page of a study submitted to EPA in support of pesticide registration. See a template for these elements. | 849 |
| Pesticide Registration Manual: Example Good Laboratory Practice Statements | 2016-11-05 | EPA 705-G-2020-0551 | Pesticide Registration Manual; GLP | Example statements related to the GLP standard. | 839 |
| Pesticide Registration Manual: Stickers For Submitted Studies - Example | 2016-11-04 | EPA 705-G-2020-0552 | Pesticide Registration Manual; Submitted Studies | Information to provide on pesticide studies submitted to EPA. | 848 |
| Pesticide Registration Manual: How to Report Changes to Company Name or Address | 2019-03-27 | EPA 705-G-2020-0554 | Pesticide Registration Manual; Report Changes Address and Company Name | Any changes to the official address, withdrawal of an existing agent, appointment of a new agent or changes to any of the contact information for the company or its agent must be reported to EPA. Find out more about how to do this. | 843 |
| Pesticide Use Site Index | 2016-12-06 | EPA 705-G-2020-0595 | Pesticide Registration; Pesticide Use Site; Index | This Pesticide Use Site Index will help a company (or other applicant) identify which data requirements are needed to register a pesticide product. | 851 |
| Child-Resistant Packaging for Pesticides | 2019-12-18 | EPA 705-G-2020-0596 | Pesticide Registration; CRP | To protect children from poisonings around the home, pesticide law requires that certain household pesticides be in child-resistant packaging. | 740 |
| Guidance on IR-4 Exemptions | 2019-03-29 | EPA 705-G-2020-0597 | PRIA Fees; IR-4 Exemptions | Information and guidance about inter-regional project 4 (IR-4) registration fee exemptions. | 764 |
| Policy on Existing Stocks of Pesticide Products | 1991-06-26 | EPA 705-G-2020-1259 | Pesticide Labels; Existing Stocks | This statement establishes general principles the Agency generally will apply in determining whether and under what conditions to allow the sale and use of existing stocks of pesticides for which the registration has been amended, canceled, or suspended. | 853 |
| Pesticide Labeling Questions & Answers | 2019-10-21 | EPA 705-G-2020-1260 | Pesticide Labels; Q & A | Pesticide manufacturers, applicators, state regulatory agencies, and other stakeholders raise questions or issues about pesticide labels. The questions on this page are those that apply to multiple products or address inconsistencies among product labels. | 809 |
| Pest Control Devices and Device Producers: 1976 Federal Register Notice | 1976-11-19 | EPA 705-G-2020-1295 | Pesticide Registration | Consolidation and clarification of requirements for pesticide devices. | 806 |
| Process for Evaluating & Implementing Alternative Approaches to Traditional in Vivo Acute Toxicity Studies for FIFRA Regulatory Use | 2016-02-04 | EPA 705-G-2020-1393 | Pesticide Science and Assessing Pesticide Risks; Alternative Approaches in Vivo Acute Toxicity | EPA’s Office of Pesticide Programs (OPP) has developed a strategic vision1 for implementing the 2007 NRC report on Toxicity Testing in the 21st Century. | 856 |
| Test Guidelines for Pesticide Data Requirements | 2017-05-23 | EPA 705-G-2020-1395 | Pesticide Science and Assessing Pesticide Risks | In evaluating a pesticide registration application, EPA assesses a wide variety of potential human health and environmental effects associated with use of the product. | 950 |
| Accelerated Storage Stability and Corrosion Characteristics Study Protocol | 2012-11-16 | EPA 705-G-2020-1490 | Pesticide Registration; Accelerated Storage Stability Corrosion Characteristics | EPA has determined that studies using this protocol will, in certain circumstances, provide the Agency with all the information it needs to make a determination on the storage stability of pesticides. | 733 |
| Protection of Proprietary Data Rights for Data Used to Support Tolerance Exemptions for Inert Ingredients | 2017-03-13 | EPA 705-G-2020-1493 | Pesticide Registration; Protection Data Rights; Inert Ingredients; Tolerance Exemptions | The FFDCA provides both exclusive use and data compensation protections for data that inert ingredient manufacturers submit to EPA to establish or maintain tolerances or tolerance exemptions for these ingredients. Find information about these protections. | 905 |
| Guidance on Efficacy Testing for Pesticides Targeting Certain Invertebrate Pests | 2019-12-13 | EPA 705-G-2020-1507 | Pesticide Registration; Efficacy Testing; Claims; Invertebrate Pests | This page is intended to help pesticide registrants complete the efficacy requirements related to invertebrate pests that may damage structures or pose significant risks to public health. | 762 |
| Pesticide Registration Manual: Example Letter for Registration or Amendment Applications Document | 2016-11-07 | EPA 705-G-2020-1620 | Pesticide Registration Manual; Examples Letter for Registration | This example letter can be used in submitting pesticide registration or amendment applications. | 840 |
| Label Review Manual Chapter 10; Revised Respirator Descriptions for Public Comment | 2018-04-12 | EPA 705-G-2020-1734 | Pesticide Registration; Label Review Manual | Revised Respirator Descriptions for Public Comment Documents | 776 |
| Spanish Translation Guide for Pesticide Labeling | 2019-10-10 | EPA 705-G-2020-2066 | Pesticide Labels | Spanish translations of health and safety information for use on pesticide product labels. | 916 |
| Inert Use Information | InertFinder | Pesticides | US EPA | 2020-01-21 | EPA 705-G-2020-2412 | inert; CAS; food; nonfood; fragrance; | InertFinder is an online database for searching substances used as inert ingredients in pesticide products. | 772 |
| Acute Oral Toxicity Up-And-Down-Procedure | 2017-03-29 | EPA 705-G-2020-2416 | acute oral toxicity; up and down; 870.1100 | Provides information on the program and associated documentation for conducting the Up-and-Down Procedure, an alternative acute toxicity test that provides a way to determine the toxicity of chemicals with fewer test animals by using sequential dosing steps. | 737 |
| Guidance on Placement of First Aid Statements on Pesticide Labels | 2018-03-08 | EPA 705-G-2020-2419 | first aid; label | In response to comments from states and pesticide registrants, EPA is releasing final guidance clarifying where first aid statements should appear on the label of pesticide products. | 765 |
| Guidance on FIFRA 24(c) Registrations | 2019-06-07 | EPA 705-G-2020-2424 | 24(c); state registration | EPA guidance (including Q&A) on registering 24(c) (Special Local Needs) registrations. | 763 |
| Suggestions for Applicants on Information Considered when Evaluating Benefits of New Conventional Active Ingredients/Significant New Use Site Requests | 2018-09-01 | EPA 705-G-2020-2432 | benefits; new active ingredient | In order to assist registrants of conventional pesticides, through this webpage, EPA is providing some suggestions on the types of information applicants could provide that would help BEAD review the benefits that accrue to potential users of the pesticide as part of the registration process. | 949 |
| Implementation Guidance for Enhanced Reporting for Registrants of Pet Spot-on Products | 2019-08-07 | EPA 705-G-2020-2435 | pet spot-on; incident reporting template | Links to the documents that provide background and summary information on the pet spot-on enhanced reporting pilot and guidance for implementing the use of standardized incident reporting templates. | 768 |
| EPA Evaluation of Pet Spot-on Products: Analysis and Plans for Reducing Harmful Effects | 2019-08-08 | EPA 705-G-2020-2436 | pet spot-on; analysis | Provides information on the EPA Evaluation of Pet Spot-on Products, the Analysis and Plans for Reducing Harmful Effects. It also includes links to enhanced reporting templates. | 751 |
| Label Guidance for Specific Types of Pesticides | 2017-10-23 | EPA 705-G-2020-2444 | warranty; repellents; antimicrobials; | Guidance on label contents as needed to clarify issues or implement program changes | 774 |
| Logos and Graphics on Pesticide Product Labels | 2019-05-21 | EPA 705-G-2020-2445 | logo; label | Guidance for applying to add a logo to a product label. | 796 |
| Pesticide Labels: Guidance on Warranty Statements | 2016-10-16 | EPA 705-G-2020-2453 | warranty; label | This guidance includes examples of improper warranty statements that go beyond what the agency considers acceptable and examples of how to fix these statements, in addition to examples of statements that are acceptable under FIFRA, and that could be incorporated into FIFRA labels. | 810 |
| Use of the Local Lymph Node Assay and Reduced Dose Protocol for LLNA in Assessing Pesticide Products | 2019-08-08 | EPA 705-G-2020-2458 | Pesticide Registration; LLNA; Reduced protocol | This policy is intended to expand the usefulness the traditional (or radiolabeled) LLNA protocol for assessment of dermal sensitization potential to single component pesticide products (i.e., technical grade active ingredients) and to pesticides with multiple components (i.e., end use products). | 955 |
| Voluntary Cancellation of a Pesticide Product or Use | 2019-12-03 | EPA 705-G-2020-2463 | Pesticide Registration; voluntary cancellation | This site provides guidance on voluntarily cancelling a pesticide use or registration. | 957 |
| Method for testing ready-to-use consumer bait stations with dogs | 2009-05-20 | EPA 705-G-2020-2468 | Pesticide Registration; bait | This protocol is designed to test the abilities of ready-to-use bait stations to isolate bait from dogs. | 800 |
| Method for testing ready-to-use bait stations with adults for facility of opening, reclosing, and securing | 1987-10-29 | EPA 705-G-2020-2469 | Pesticide Registration; bait | This protocol is designed to test the reliability with which untrained adults can perform tasks necessary for proper use of ready-to-use bait stations. | 798 |
| Method for testing ready-to-use bait stations with young children | 1987-10-29 | EPA 705-G-2020-2470 | Pesticide Registration; bait | This protocol is designed to test the abilities of ready-to-use bait stations to isolate bait from children of pre-school age. | 799 |
| Standard norway rat/roof rat anticoagulant technical and concentrated dry bait laboratory test method | 1976-05-06 | EPA 705-G-2020-2471 | Pesticide Registration; bait | This method is designed to determine the effectiveness of dry bait anticoagulant technical and concentrated rodenticide products for standard Norway and roof rats. | 939 |
| Standard mouse acute placepack dry bait laboratory test method | 1976-09-01 | EPA 705-G-2020-2472 | Pesticide Registration; bait | This method is designed to determine the effectiveness of acute dry bait rodenticide products used in placepacks for control of house mice. | 929 |
| Standard norway rat and roof rat acute placepack dry bait laboratory test method | 1976-09-01 | EPA 705-G-2020-2473 | Pesticide Registration; bait | This method is designed to determine the effectiveness of acute dry bait rodenticide products used in placepacks for control of Norway and roof rats. | 930 |
| Standard house mouse anticoagulant placepack penetration laboratory test method | 1975-01-01 | EPA 705-G-2020-2474 | Pesticide Registration; bait | This method is designed to determine the effectiveness of anticoagulant dry bait rodenticide products used in placepacks for house mouse control. | 925 |
| Standard norway rat and roof rat anticoagulant placepack dry bait laboratory test method | 1975-01-01 | EPA 705-G-2020-2475 | Pesticide Registration; bait | This method is designed to determine the effectiveness of anticoagulant dry bait rodenticide products used in placepacks for rat control. | 932 |
| Standard peromyscus species anticoagulant dry bait laboratory test method | 1975-01-01 | EPA 705-G-2020-2476 | Pesticide Registration; bait | This method is designed to determine the effectiveness of ready-to-use dry bait anticoagulant rodenticide products used for control of Peromyscus spp. | 943 |
| Standard peromyscus species acute dry bait laboratory test method | 1975-01-01 | EPA 705-G-2020-2477 | Pesticide Registration; bait | This method is designed to determine the effectiveness of acute dry bait rodenticide products used for control of Peromyscus spp. | 941 |
| Standard house mouse anticoagulant wax block and wax pellet laboratory test method | 1975-01-01 | EPA 705-G-2020-2478 | Pesticide Registration; wax block and pellet | This method is designed to determine the effectiveness anticoagulant rodenticide products claimed to be suitable to use for house mouse control in wet or damp environments. | 928 |
| Standard norway rat anticoagulant wax block and wax pellet laboratory test method | 1990-12-02 | EPA 705-G-2020-2479 | Pesticide Registration; wax block and pellet | This method is designed to determine the effectiveness anticoagulant rodenticide products claimed to be suitable to use for rat control in wet or damp environments. | 933 |
| Standard house mouse anticoagulant tracking powder efficacy laboratory test method | 1991-09-27 | EPA 705-G-2020-2480 | Pesticide Registration; powder | This method is designed to determine the effectiveness of anticoagulant tracking powder rodenticide products for house mice. | 927 |
| Standard norway rat/roof rat acute tracking powder efficacy laboratory test method | 1992-12-17 | EPA 705-G-2020-2481 | Pesticide Registration; powder | This method is designed to determine the effectiveness of acute tracking powder used for control of Norway or roof rats. | 937 |
| Standard house mouse acute dry bait laboratory test method | 1991-10-08 | EPA 705-G-2020-2482 | Pesticide Registration; bait | This method is designed to determine the effectiveness of ready-to-use acute dry bait rodenticide products used for house mouse control. | 919 |
| Standard norway rat/roof rat acute dry bait laboratory test method | 1991-10-08 | EPA 705-G-2020-2483 | Pesticide Registration; bait | This method is designed to determine the effectiveness of ready-to-use acute dry bait rodenticide products used for rat control. | 934 |
| Standard house mouse acute liquid bait laboratory test method | 1991-09-27 | EPA 705-G-2020-2484 | Pesticide Registration; bait | This method is designed to determine the effectiveness of acute rodenticide products used to make liquid baits for controlling house mice. | 920 |
| Standard norway rat/roof rat acute liquid bait laboratory test method | 1991-06-19 | EPA 705-G-2020-2485 | Pesticide Registration; bait | This method is designed to determine the effectiveness of products used in acute liquid bait rodenticides used to control Norway and roof rats | 935 |
| Standard norway rat/roof rat anticoagulant tracking powder efficacy laboratory test method | 1991-06-19 | EPA 705-G-2020-2486 | Pesticide Registration; powder | This method is designed to determine the effectiveness of anticoagulant tracking powder rodenticide products for rats. | 940 |
| Standard house mouse anticoagulant dry bait laboratory test method | 1991-06-18 | EPA 705-G-2020-2487 | Pesticide Registration; bait | This method is designed to determine the effectiveness of dry bait anticoagulant rodenticide products used for control of house mice. | 923 |
| Standard norway rat/roof rat anticoagulant dry bait laboratory test method | 1991-06-18 | EPA 705-G-2020-2488 | Pesticide Registration; bait | This method is designed to determine the effectiveness of ready-to-use dry bait anticoagulant rodenticide products used for control of rats. | 938 |
| Standard house mouse anticoagulant liquid bait laboratory test method | 1991-06-17 | EPA 705-G-2020-2489 | Pesticide Registration; bait | This method is designed to determine the effectiveness of anticoagulant rodenticide products used to make liquid baits for controlling house mice. | 924 |
| Standard norway rat and roof rat anticoagulant liquid bait laboratory test method | 1991-06-16 | EPA 705-G-2020-2490 | Pesticide Registration; bait | This method is designed to determine the effectiveness of anticoagulant rodenticide products used to make liquid baits for controlling commensal rats. | 931 |
| Standard house mouse acute tracking powder efficacy laboratory test method | 1992-12-15 | EPA 705-G-2020-2491 | Pesticide Registration; powder | This method is designed to determine the effectiveness of acute tracking powder for house mice. | 922 |
| Standard house mouse acute technical and concentrated dry bait laboratory test method | 1992-12-14 | EPA 705-G-2020-2492 | Pesticide Registration; bait | This method is designed to determine the effectiveness of dry bait technical and concentrated acute rodenticide products for house mice. | 921 |
| Standard house mouse anticoagulant technical and concentrated dry bait laboratory test method | 1992-12-13 | EPA 705-G-2020-2493 | Pesticide Registration; bait | This method is designed to determine the effectiveness of dry bait anticoagulant technical and concentrated rodenticide products for standard house mice. | 926 |
| Standard peromyscus species acute technical and concentrated dry bait laboratory test method | 1992-12-15 | EPA 705-G-2020-2494 | Pesticide Registration; bait | This method is designed to determine the effectiveness of ready-to-use dry bait technical and concentrated acute rodenticide products for Peromyscus spp. | 942 |
| Standard peromyscus species anticoagulant technical and concentrated dry bait laboratory test method | 1992-12-15 | EPA 705-G-2020-2495 | Pesticide Registration; bait | This method is designed to determine the effectiveness of ready-to-use dry bait anticoagulant technical and concentrated rodenticide products used for control of Peromyscus spp. | 944 |
| Standard norway rat/roof rat acute technical and concentrated dry bait laboratory test method | 1992-12-13 | EPA 705-G-2020-2496 | Pesticide Registration; bait | This method is designed to determine the effectiveness of dry bait technical and concentrated acute rodenticide products for standard Norway and roof rats. | 936 |
| EPA Response to letter dated August 31, 2018, regarding disruptions in availability of 1,2-benzisothiazolin-3-one (BIT) and the self-certification process. | 2018-10-18 | EPA 705-G-2020-2498 | Pesticide Registration; BIT self-certification | This letter is in response to a registrant letter requesting the incorporation of further clarifications and additions to EPA’s August 23, 2018, letter addressing disruptions in availability of 1,2 benzisothiazolin-3-one (BIT) and providing for a streamlined self-certification process. | 752 |
| Response to letter dated November 8, 2018, requesting that the Agency expand the expedited process for minor formulation amendments (MFAs) described in our October 18, 2018, letter | 2018-12-21 | EPA 705-G-2020-2499 | Pesticide Registration; MFA | This letter contains the Agency's response to a registrant letter regarding expanding the expedited process for minor formulation amendments | 914 |
| Response to letter dated July 27, 3018, concerning a situation where an unforeseen foreign production site closure has led to disruption in availability of 1,2-benzisothiazolin-3-one (BIT) (CAS Reg. No. 2634-33-5) | 2018-08-23 | EPA 705-G-2020-2500 | Pesticide Registration; BIT self-certification | This letter contains the Agency's response to a registrant letter regarding a request for self-certification when an unforeseen foreign production site closure has led to a disruption in availability of BIT. | 913 |
| State FIFRA Issues, Research, and Evaluation Group Final Guidance for State Lead Agencies for the Development and Implementation of Managed Pollinator Protection Plans | 2015-04-03 | EPA 705-G-2020-2504 | Pollinator Protection | This document contains guidance for states on the development and implementation of managed pollinator protection plans. | 945 |
| EPA Actions to Protect Pollinators | 2017-10-23 | EPA 705-G-2020-2507 | Pollinator Protection | This page contains a summary of EPA's actions to protect pollinators from pesticide exposure. | 750 |
| U.S. Environmental Protection Agency's Policy to Mitigate the Acute Risk to Bees from Pesticide Products | 2017-01-12 | EPA 705-G-2020-2770 | Pollinator Protections; bees | Policy document describing the EPA's approach to mitigate acute risk from pesticides to bees. | 953 |
| Regulation of Pesticide Residues on Food | 2019-04-30 | EPA 705-G-2020-2787 | Pesticide Registration; tolerances | This page provides links to guidance about tolerances. | 910 |
| Notifying the Public about Pesticide Tolerances | 2017-02-09 | EPA 705-G-2020-2789 | Pesticide Registration; tolerances; notice to public | This page includes summary information about a notice of filing of a petition to establish a tolerance, emergency exemptions, establishing tolerances and exemptions, revoking tolerances, and tolerance objections. | 804 |
| Pesticide Cancellation Under EPA's Own Initiative | 2018-11-07 | EPA 705-G-2020-2790 | Pesticide Registration; tolerances; cancellation | Cancellation of a pesticide registration may be initiated by EPA after the Agency has evaluated the potential risks and benefits associated with registered uses of a pesticide. This page describes steps leading to cancellation. | 807 |
| How to Search for Tolerances for Pesticide Ingredients in the Code of Federal Regulations | 2018-04-02 | EPA 705-G-2020-2794 | Pesticide Registration; tolerances; MRLs | This page provides instructions and links to searching for tolerances. | 767 |
| Strategic Vision for Adopting 21st Century Science Methodologies | 2018-04-10 | EPA 705-G-2020-2801 | Pesticide Registration; Risk Assessment; integrated approaches to testing and assessment (IATA) | This guidance relates to the use of new technologies in molecular, cellular, computational sciences to supplement or replace traditional methods of toxicity testing and risk assessment. | 946 |
| Guiding Principles for Data Requirements | 2013-05-31 | EPA 705-G-2020-2803 | Pesticide Registration; data requirements | PDF that summarizes how/why EPA exercises its authority to require certain data it deems necessary to support regulatory decisions | 766 |
| Non-Animal Testing Approach to EPA Labeling for Eye Irritation | 2017-05-03 | EPA 705-G-2020-2806 | Pesticide Registration; non-animal testing; eye irritation | This is a webpage describing alternative in vitro/ex vivo assays for the eye irritation test | 803 |
| Guidance for Identifying, Selecting and Evaluating Open Literature Studies | 2017-10-03 | EPA 705-G-2020-2815 | Pesticide Registration; literature evaluation; risk assessment | This is a web page providing guidance on how to evaluate open literature data to support pesticide applications, and also how EPA itself evaluates open literature for use in the risk assessment process. | 760 |
| Controlling Rodents and Regulating Rodenticides | 2018-07-10 | EPA 705-G-2020-2837 | Rodents, Rodenticides, regulating | Site with multiple links. | 741 |
| Spot-On Enhanced Reporting Pilot Template Development Synopsis | 2018-01-23 | EPA 705-G-2020-2839 | pets, spot-on Products; reporting sales and incident | Spot-On Enhanced Reporting Pilot Template Development Synopsis PDF. | 918 |
| About Pesticide Registration - Pesticide Registration | 2019-06-26 | EPA 705-G-2020-2843 | Pesticide Registration | Describes the process for evaluating pesticide registration applications - human health and environmental risk considerations. | 731 |
| Pesticide Emergency Exemptions | 2019-11-07 | EPA 705-G-2020-2845 | Pesticide Registration; evaluation criteria; emergency exemptions | Provides details on types and evaluation criteria for emergency exemptions. | 808 |
| Minor Uses and Grower Resources | 2019-08-02 | EPA 705-G-2020-2848 | exclusive use; minor use | Provides information on Minor Use Crops and Pesticides, International MRLs, NAFTA Minor Use Joint Reviews, Crop Grouping, Exclusive Use Periods, Definition of a Minor Use, Establishing or Extending Exclusive Use Periods. | 802 |
| Pesticide Registration Policy and Guidance | 2018-04-10 | EPA 705-G-2020-2849 | Pesticide Registration; toxicity testing; human; human studies | This page lists toxicity testing topics and guidance, protection of human test subjects, additional guidance and policy information. | 850 |
| Draft Waiver Guidance on Dermal Toxicity Testing: Retrospective Analysis and Guidance for Waiving Acute Dermal Toxicity Tests for Pesticide Formulations | 2016-03-11 | EPA 705-G-2020-2854 | Pesticide Registration; toxicity testing; waiving | This page provides a link to guidance for waiving dermal toxicity data. | 747 |
| User Documentation for the AOT425StatPgm Program | 2003-06-01 | EPA 705-G-2020-2859 | acute oral toxicity; up and down; 870.1100; OECD 425 | Guidance for how to use the AOT425StatPgm Program. | 956 |
| OECD Guideline for Testing of Chemicals | 2001-12-17 | EPA 705-G-2020-2860 | acute oral toxicity; up and down; 870.1100; OECD 425 | Guidance providing information and descriptions on the OECD Test Guideline 425, how to perform the studies and what data needs to be submitted. | 805 |
| QA Testing for the AOT425StatPgm Program | 2001-06-01 | EPA 705-G-2020-2861 | acute oral toxicity; up and down; 870.1100; OECD 425 | Guidance for how to use the AOT425StatPgm Program; description of the model, how to use, how to construct data sets and compare. | 906 |
| Toxicology Guidance: Performance of the Up-and-Down Procedure | 2017-03-29 | EPA 705-G-2020-2862 | acute oral toxicity; up and down; 870.1100; OECD 425 | This summary is intended to accompany the Up-and-Down Procedure (UDP) test guideline and the AOT425StatPgm program and assist the user in interpreting its output. The UDP guideline uses the maximum likelihood estimation method for calculation of the LD50 and profile likelihood (PL) methods for estimation of most confidence intervals. This summary addresses choice of dose progression and initial dose level for the UDP and describes the performance of the test under a variety of circumstances. | 951 |
| Crosswalk of Paragraphs: OPPTS 870.1100 versus OECD 425 Acute Oral Toxicity: Up-and-Down Procedure | 2017-03-29 | EPA 705-G-2020-2863 | acute oral toxicity; up and down; 870.1100; OECD 425 | Guidance on relationship and cross-walk between OPPTS 870.1100 guideline and OECD 425 guideline. | 744 |
| Elements of an Offer to Pay for the Use of Inert Ingredient Data | 2019-10-17 | EPA 705-G-2020-2865 | Data Compensation Inert Ingredient | This link offers guidance on elements that should be included in an Offer to Pay for the use of Inert ingredient data. | 748 |
| Pet Spot-on Enhanced Reporting Implementation Guidance (PDF) | 2018-02-01 | EPA 705-G-2020-2870 | Standardized Templates, Enhanced Reporting, Incident, Sales, Mitigation, Implementation; Conditions of Registration, expiration | PDF of Guidance to use EPA's Standardized Incident and Sales Templates for enhanced reporting of adverse incidents and requesting changes to conditions of registration (Quarterly to Annual submission of enhanced reporting; Removal of 2-year expiration date); Webinar took place 5/10/2018; PDF first dated February 2018 and updated August 2019 | 852 |
| Spot-on Enhanced Reporting Pilot Concluding Webinar and Implementation (PDF) | 2018-05-10 | EPA 705-G-2020-2871 | Standardized Templates, Enhanced Reporting, Incident, Sales, Mitigation, Implementation; Conditions of Registration, expiration | PDF of Webinar PowerPoint presentation. | 917 |
| Enhanced Incident Reporting Template (XLSX) | 2017-03-01 | EPA 705-G-2020-2872 | Enhanced reporting, adverse incident, pet spot-on | EPA's standardized template for submission of enhanced reporting for adverse incidents | 749 |
| Sales Reporting Template (XLSX) | 2017-03-01 | EPA 705-G-2020-2873 | Enhanced reporting, adverse incident, pet spot-on, sales | EPA's standardized template for submission of corresponding enhanced reporting sales data | 915 |
| Meetings with Manufacturers of Pet Spot-on Products | 2009-01-01 | EPA 705-G-2020-2874 | Pet spot-on, mitigation, adverse effect, adverse incident, dog, cat | Web page includes sections: Summary of Meetings we held with the Product Registrants; Generic mitigation table provided to product registrants; next steps. | 797 |
| Data Requirements for Pesticide Registration | 2019-06-26 | EPA 705-G-2020-2894 | Pesticide Registration - data | Data Requirements to Register a Pesticide | 745 |
| Understanding the Science behind EPA’s Pesticide Decisions | 2019-08-02 | EPA 705-G-2020-2898 | Pesticide Registration | Understanding the Science behind EPA’s Pesticide Decisions | 954 |
| Repellency Awareness Graphic | 2016-01-01 | EPA 705-G-2020-2902 | Pesticide Registration | Overview of the repellency awareness graphic | 911 |
| Formulation / End-use Product - Product Chemistry Evaluation (based on OECD Dossier Numbering) Identity, Physical and Chemical Properties, Analytical Methods, Confidential Information | 2016-05-01 | EPA 705-G-2020-2916 | Pesticide registration, product chemistry | The study profile template describes the layout and scope of information that should be contained within a study profile and can serve as a guide for the preparation of the study document. | 756 |
| General Guidance for Petitioning the Agency for the Establishment of a New/Amended Food Use Inert Ingredient Tolerance or Tolerance Exemption under PRIA 3 | 2013-01-08 | EPA 705-G-2020-2923 | Pesticide Registration | Guidance for new/amended food use inert ingredient tolerance or tolerance exemption | 757 |
| General Guidance for Requesting the Establishment of a Tolerance Exemption for a Low Risk Polymer or Nonfood Use Approval of a Low Risk Polymer under PRIA 3 | 2013-01-23 | EPA 705-G-2020-2924 | Pesticide Registration | Guidance for establishing tolerance exemption for low risk polymer or nonfood use approval of low risk polymers | 759 |
| General Guidance for Requesting the Approval of a New Nonfood Use Inert Ingredient1 or Amending a Currently Approved Nonfood Use Inert Ingredient under PRIA 3 | 2013-01-23 | EPA 705-G-2020-2925 | Pesticide Registration | Guidance for requesting the approval of a new nonfood use inert ingredient or amending a currently approved nonfood use inert ingredient | 758 |
| List of Trade Name Inert Ingredients | 2014-02-05 | EPA 705-G-2020-2927 | Pesticide Registration | EPA’s Office of Pesticide Programs (OPP) has developed a list of trade names for inert ingredients used pesticide products registered under FIFRA. | 795 |
| Trade Name Database | 2020-02-14 | EPA 705-G-2020-2934 | Pesticide registration, inerts | The List of Trade Names of Inert Ingredients database is intended solely to enhance public access to information related to the EPA approval status of trade name inert ingredients used in pesticide products. | 952 |
| Inert Ingredient Frequently Asked Questions | 2015-12-01 | EPA 705-G-2020-2937 | Pesticide registration, inerts | This document answers frequently asked questions about inert ingredients | 770 |
| Pesticide Registration Manual: Chapter 8 - Inert Ingredients | 2017-05-24 | EPA 705-G-2020-2940 | Pesticide Registration | This chapter describes how EPA reviews inert ingredients as part of the pesticide product review process. | 836 |
| Label Review Manual, Chapter 1: Purpose of the Manual | 2016-12-01 | EPA 705-G-2020-2941 | Pesticide Registration | This chapter describes the purpose of the Label Review Manual. | 786 |
| Label Review Manual, Chapter 2: What is a Pesticide? | 2021-01-19 | EPA 705-G-2020-2942 | Pesticide Registration | This chapter describes what a pesticide is. | 787 |
| Label Review Manual, Chapter 3: General Labeling Requirements | 2018-03-01 | EPA 705-G-2020-2943 | Pesticide Registration | This chapter describes general labeling requirements. | 788 |
| Label Review Manual, Chapter 4: Types of Label Reviews | 2011-12-01 | EPA 705-G-2020-2944 | Pesticide Registration | This chapter describes types of label reviews. | 789 |
| Label Review Manual, Chapter 5: Ingredient Statements | 2012-03-01 | EPA 705-G-2020-2945 | Pesticide Registration | This chapter describes the ingredient statement on the pesticide label. | 790 |
| Label Review Manual, Chapter 6: Use Classification | 2012-01-01 | EPA 705-G-2020-2946 | Pesticide Registration | This chapter describes the use classifications on the label. | 791 |
| Label Review Manual, Chapter 7: Precautionary Statements | 2018-03-01 | EPA 705-G-2020-2947 | Pesticide Registration | This chapter describes the precautionary statements on the label. | 792 |
| Label Review Manual, Chapter 8: Environmental Hazards | 2012-09-01 | EPA 705-G-2020-2948 | Pesticide Registration | This chapter describes the environmental hazards section on the label. | 793 |
| Label Review Manual, Chapter 9: Physical or Chemical Hazards | 2012-09-01 | EPA 705-G-2020-2949 | Pesticide Registration; Pesticide Labeling | This chapter describes the physical or chemical hazards section on the label. | 794 |
| Label Review Manual, Chapter 10: Worker Protection Label | 2016-02-01 | EPA 705-G-2020-2950 | Pesticide Registration; Pesticide Labeling | This chapter describes worker protection labeling. | 777 |
| Label Review Manual, Chapter 11: Directions for Use | 2014-12-01 | EPA 705-G-2020-2951 | Pesticide Registration; Pesticide Labeling | This chapter describes the directions for use section of the label. | 778 |
| Label Review Manual, Chapter 12: Labeling Claims | 2013-11-01 | EPA 705-G-2020-2952 | Pesticide Registration; Pesticide Labeling | This chapter discusses claims made on labels. | 779 |
| Label Review Manual, Chapter 13: Storage and Disposal | 2013-07-01 | EPA 705-G-2020-2953 | Pesticide Registration; Pesticide Labeling | This chapter describes the storage and disposal section of the label. | 780 |
| Label Review Manual, Chapter 14: Identification Numbers | 2012-11-01 | EPA 705-G-2020-2954 | Pesticide Registration; Pesticide Labeling | This chapter describes identification numbers on labels. | 781 |
| Label Review Manual, Chapter 15: Company Name and Address | 2017-08-01 | EPA 705-G-2020-2955 | Pesticide Registration; Pesticide Labeling | This chapter describes listing the company name and number on the label. | 782 |
| Label Review Manual, Chapter 16: Graphics and Symbols | 2017-08-01 | EPA 705-G-2020-2956 | Pesticide Registration; Pesticide Labeling | This chapter describes graphics and logos listed on labels. | 783 |
| Label Review Manual, Chapter 17: Net Contents/Net Weight | 2018-02-01 | EPA 705-G-2020-2957 | Pesticide Registration; Pesticide Labeling | This chapter describes the net contents and net weight located on the label. | 784 |
| Label Review Manual, Chapter 18: Unique Product Labeling | 2013-09-01 | EPA 705-G-2020-2958 | Pesticide Registration; Pesticide Labeling | This chapter describes unique product labeling. | 785 |
| Guidance for Pesticide Registrants on Location of the First Aid Statement and Clarification on Definition of Label "Panel" per 40 CFR 156.68 | 2016-12-07 | EPA 705-G-2020-2961 | First Aid Statement; Pesticide Labeling | Clarification memo on the Agency's interpretation of the word "panel" in the context of 40 CFR 156.68 including where First Aid statements must appear on a product's label based on the product's toxicity category. | 761 |
| First Aid Guidance Document – EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement per 40 CFR 156.68. (Docket ID: EPA-HQ-OPP-2016-0545) | 2018-03-07 | EPA 705-G-2020-2963 | First Aid Statements; Pesticide Labeling | This document summarizes the EPA's decision regarding the interpretation of the term “panel” in the context of 40 CFR 156.68 and includes a clarification regarding where first aid statements must appear on pesticide labels based on the product’s Toxicity Category. | 753 |
| First Aid Guidance: Response to Public Comments on EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement and Clarification on Definition of Label “Panel” per 40 CFR 156.68. (Docket ID: EPA-HQ-OPP-2016-0545) | 2018-03-07 | EPA 705-G-2020-2964 | First Aid Statements; Pesticide Labeling | This document summarizes the EPA's response to public comments on its memorandum to clarify the interpretation of the term “panel” in the context of 40 CFR 156.68 and to clarify where first aid statements must appear on pesticide labels based on the product’s Toxicity Category. | 754 |
| Minor revisions to “First Aid Guidance Document – EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement per 40 CFR 156.68” and Response to Public Comments | 2018-03-07 | EPA 705-G-2020-2965 | First Aid Statement; Pesticide Labeling | The purpose of this note is to clarify minor changes made to the documents titled “First Aid Guidance Document – EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement per 40 CFR 156.68” and “First Aid Guidance: Response to Public Comments on EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement and Clarification on Definition of Label “Panel” per 40 CFR 156.68” located in docket EPA-HQ-OPP-2016-0545 on www.regulations.gov. | 801 |
| Questions and Answers - Exclusive Use Data Protection for Minor Use Registrations | 2018-02-01 | EPA 705-G-2020-2970 | Exclusive Use; Minor Use; Pesticide Registration | This document contains guidance on Exclusive Use Data Protection for Minor Use Registrations. | 907 |
| Questions and Answers - Extension of Exclusive Data and Minor Use Designation, Suggestions to Applicants for Agronomic Information | 2016-11-01 | EPA 705-G-2020-2971 | Exclusive Use; Minor Use; Pesticide Registration | This document contains guidance for extending exclusive data and requesting minor use designation. | 908 |
| About Risk Assessment | 2020-01-06 | EPA 705-G-2020-2975 | Pesticide Risk Assessment | Webpage containing information regarding risk assessment basics. | 732 |
| Indexes to Part 180 Tolerance Information for Pesticide Chemicals in Food and Feed Commodities | 2017-05-23 | EPA 705-G-2020-2976 | Pesticide Tolerances | Webpage describing information that may be helpful in finding specific pesticide tolerance information available in the CFR at Part 180. | 769 |
| Application Submission and Screening | 2016-08-22 | EPA 705-G-2020-2979 | Pesticide Registration | High-level overview page with links to various component checklists for pesticide registration application submissions. | 738 |
| Ingredients Used in Pesticide Products | 2019-04-30 | EPA 705-G-2020-2986 | Pesticide Registration | Links to pesticide information, groups, inerts, and databases. | 773 |
| Repellents: Protection against Mosquitoes, Ticks and Other Arthropods | 2019-04-30 | EPA 705-G-2020-2987 | Pesticide Regulation | This page offers information about preventing bites and insect repellents and includes links to related guidance. | 912 |
| Protecting Pets from Fleas and Ticks | 2018-10-17 | EPA 705-G-2020-2988 | Pesticide Registration | Links to information about controlling fleas, ticks and other related guidance. | 904 |
| Food and Pesticides | 2019-03-06 | EPA 705-G-2020-2994 | Pesticide Registration | Page includes information about pesticides on food and how this is regulated; it includes links to related guidance. | 755 |
| Product Chemistry for Technical Grade of the Active Ingredient or Manufacturing Use Products (Group A and B data) | 2016-05-01 | EPA 705-G-2020-3292 | Study Profile Template | Study profile template for product chemistry evaluation | 858 |
| Product Chemistry for End Use Products | 2006-05-01 | EPA 705-G-2020-3293 | product chemistry | Template for product chemistry of end use products | 857 |
| Acute Oral Toxicity - [species] | 2004-05-01 | EPA 705-G-2020-3329 | Study Profile Template | Study profile template for acute oral toxicity study | 736 |
| Acute Dermal Toxicity - [species] | 2004-05-01 | EPA 705-G-2020-3330 | Study Profile Template | Study profile template for acute dermal toxicity study | 734 |
| Acute Inhalation Toxicity - [species] | 2004-05-01 | EPA 705-G-2020-3331 | Study Profile Template | Study profile template for acute inhalation toxicity study | 735 |
| Primary Eye Irritation - [species] | 2004-05-01 | EPA 705-G-2020-3332 | Study Profile Template | Study profile template for primary eye irritation study | 855 |
| Primary Dermal Irritation - [species] | 2004-05-01 | EPA 705-G-2020-3333 | Study Profile Template | Study profile template for primary dermal irritation study | 854 |
| Dermal Sensitization - [species] | 2004-05-01 | EPA 705-G-2020-3334 | Study Profile Template | Study profile template for dermal sensitization study | 746 |
| Pesticide Submissions Portal (PSP) - CDX User Guide | 2021-08-13 | EPA 705-G-2021-3739 | CDX user guide for the submission of pesticides including registration, notifications, petitions, data call-ins, and acknowledgements. | 1014 | |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3800, Methods for Efficacy Testing of Termite Baits | 2004-08-01 | EPA 712-C-04-371 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 865 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3700, Insect Repellents to be Applied to Human Skin | 2010-07-07 | EPA 712-C-10-001 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 864 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3900, Laboratory Product Performance Testing Methods for Bed Bug Pesticide Products | 2017-06-01 | EPA 712-C-17-001 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 866 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3500, Premises Treatments | 2019-08-28 | EPA 712-C-19-001 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 862 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1550, Product Identity and Composition | 1996-08-01 | EPA 712-C-96-006 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 895 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1600, Description of Materials Used to Produce the Product | 1996-08-01 | EPA 712-C-96-007 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 896 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1620, Description of Production Process | 1996-08-01 | EPA 712-C-96-008 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 897 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1650, Description of Formulation Process | 1996-08-01 | EPA 712-C-96-009 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 898 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1670, Discussion of Formation of Impurities | 1996-08-01 | EPA 712-C-96-010 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 899 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1700, Preliminary Analysis | 1996-08-01 | EPA 712-C-96-011 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 900 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1750, Certified Limits | 1996-08-01 | EPA 712-C-96-012 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 901 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1800, Enforcement Analytical Method | 1996-08-01 | EPA 712-C-96-013 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 902 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6302, Color | 1996-08-01 | EPA 712-C-96-019 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 870 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6303, Physical State | 1996-08-01 | EPA 712-C-96-020 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 871 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6304, Odor | 1996-08-01 | EPA 712-C-96-021 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 872 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6313, Stability to Normal and Elevated Temperatures, Metals, and Metal Ions | 1996-08-01 | EPA 712-C-96-022 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 873 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6314, Oxidation/Reduction: Chemical Incompatibility | 1996-08-01 | EPA 712-C-96-023 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 874 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6315, Flammability | 1996-08-01 | EPA 712-C-96-024 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 875 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6316, Explodability | 1996-08-01 | EPA 712-C-96-025 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 876 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6317, Storage Stability | 2002-06-01 | EPA 712-C-96-026 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 877 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6319, Miscibility | 1996-08-01 | EPA 712-C-96-027 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 878 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6320, Corrosion Characteristics | 1996-08-01 | EPA 712-C-96-028 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 879 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6321, Dielectric Breakdown Voltage | 1996-08-01 | EPA 712-C-96-029 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 880 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7000, pH | 1996-08-01 | EPA 712-C-96-030 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 881 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7050, UV/Visible Absorption | 1996-08-01 | EPA 712-C-96-031 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 882 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7100, Viscosity | 1996-08-01 | EPA 712-C-96-032 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 883 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7200, Melting Point/Melting Range | 1998-03-01 | EPA 712-C-96-033 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 884 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7220, Boiling Point/Boiling Range | 1996-08-01 | EPA 712-C-96-034 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 885 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7300, Density/Relative Density/Bulk Density | 2002-06-01 | EPA 712-C-96-035 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 886 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7370, Dissociation Constants in Water | 1996-08-01 | EPA 712-C-96-036 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 887 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7520, Particle Size, Fiber Length, and Diameter Distribution | 1996-08-01 | EPA 712-C-96-037 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 888 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7550, Partition Coefficient (n-octanol/water), Shake Flask Method | 1996-08-01 | EPA 712-C-96-038 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 889 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7560, Partition Coefficient (n-octanol/water), Generator Column Method | 1996-08-01 | EPA 712-C-96-039 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 890 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7570, Partition Coefficient (n-octanol/water), Estimation by Liquid Chromatography | 1996-08-01 | EPA 712-C-96-040 | Test Guideline; Product Properties; Partition Coefficient | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 891 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7840, Water Solubility: Column Elution Method; Shake Flask Method | 1998-03-01 | EPA 712-C-96-041 | Test Guideline; Product Properties; Water Solubility | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 892 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7860, Water Solubility, Generator Column Method | 1998-03-01 | EPA 712-C-96-042 | Test Guideline; Product Properties; Water Solubility | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 893 |
| Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7950, Vapor Pressure | 1996-08-01 | EPA 712-C-96-043 | Test Guideline; Product Properties; Vapor Pressure | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 894 |
| Product Properties Test Guidelines: 830.1000, Background for Product Properties Test Guidelines | 1998-03-01 | EPA 712-C-96-310 | Test Guideline; Product Properties; Background | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 869 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3000, General Considerations for Efficacy of Invertebrate Control Agents | 1998-03-01 | EPA 712-C-98-409 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 859 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, OCSPP 810.3100, Treatments for Imported Fire Ants | 2021-01-19 | EPA 712-C-98-410 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 867 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, OCSPP 810.3300, The Efficacy of Topically Applied Pet Products Against Certain Invertebrate Pests | 2021-01-19 | EPA 712-C-98-411 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 868 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3200, Livestock, Poultry, Fur- and Wool-bearing Animal Treatments | 1998-03-01 | EPA 712-C-98-414 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 860 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3400, Mosquito, Black Fly, and Biting Midge (Sand Fly) Treatments | 1998-03-01 | EPA 712-C-98-419 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 861 |
| Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3600, Structural Treatments | 1998-03-01 | EPA 712-C-98-424 | Test Guideline; Product Performance | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 863 |
| Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1900, Submittal of Samples | 2008-11-01 | EPA 712-F-08-002 | Test Guideline; Product Properties | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 903 |
| Amphibian Metamorphosis Assay | 2011-09-01 | EPA 705-G-2020-3369 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Amphibian Metamorphosis Assay, 890.1100, Study Profile Template. | 959 |
| Androgen Receptor Binding (Rat Prostate) | 2011-10-01 | EPA 705-G-2020-3370 | Endocrine Disruptor Testing, test guideline, Androgen Receptor Binding (Rat Prostate), 890.1150, Study Profile Template, SPT | Androgen Receptor Binding (Rat Prostate), 890.1150, Study Profile Template. | 960 |
| Aromatase (Human Recombinant) | 2011-07-01 | EPA 705-G-2020-3371 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Aromatase (Human Recombinant), 890.1200, Study Profile Template | 963 |
| Estrogen Receptor Binding | 2011-10-01 | EPA 705-G-2020-3372 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Estrogen Receptor Binding, 890.1250, Study Profile Template | 992 |
| Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903) | 2011-08-01 | EPA 705-G-2020-3373 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903), 890.1300, Study Profile Template | 995 |
| Fish Short-Term Reproduction | 2011-10-01 | EPA 705-G-2020-3374 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Fish Short-Term Reproduction 890.1350, Study Profile Template | 999 |
| Hershberger (Rat) | 2011-10-01 | EPA 705-G-2020-3375 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Hershberger, 890.1400, Study Profile Template | 1001 |
| Female Pubertal (Rat) | 2011-08-01 | EPA 705-G-2020-3376 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Female Pubertal (Rat), 890.1450, Study Profile Template | 997 |
| Male Pubertal (Rat) | 2011-08-01 | EPA 705-G-2020-3377 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Male Pubertal (Rat), 890.1500, Study Profile Template. | 1004 |
| Steroidogenesis (Human Cell Line – H295R) | 2011-07-01 | EPA 705-G-2020-3378 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Steroidogenesis (Human Cell Line - H295R), 890.1550, Study Profile Template | 1006 |
| Uterotrophic (Rat) | 2011-09-01 | EPA 705-G-2020-3379 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT | Uterotrophic (Rat), 890.1600, Study Profile Template | 1008 |
| Endocrine Disruptor Screening Program Tier 1 Assays: Considerations for Use in Human Health and Ecological Risk Assessments | 2013-06-01 | EPA 705-G-2020-3553 | Endocrine Disruptor Screening Program, EDSP, Tier 1, testing | Guidance for the conduct of Tier 1 screening assays for endocrine disruption effects. | 982 |
| Endocrine Disruptor Screening Program | 1998-08-11 | EPA 705-G-2020-3563 | Endocrine Disruptor Screening Program; EDSP; Policy; EDSTAC | Policy Notice; EPA's Initial outline of the Endocrine Disruptor Screening Program (EDSP) | 965 |
| Endocrine Disruptor Screening Program; Proposed Statement of Policy | 1998-12-28 | EPA 705-G-2020-3564 | Endocrine Disruptor Screening Program; EDSP; Policy; EDSTAC | Policy Notice; Further additional details of the Endocrine Disruptor Screening Program (EDSP) | 991 |
| Endocrine Disruptor Screening Program Universe of Chemicals and General Validation Principles | 2012-11-01 | EPA 705-G-2020-3569 | Endocrine Disruptor Screening Program; EDSP; EDSP Universe of Chemicals; EDSP General Validation Principles | U.S. Environmental Protection Agency Endocrine Disruptor Screening Program Universe of Chemicals and General Validation Principles. A Guidance document jointly developed by the Office of Chemical Safety & Pollution Prevention, the Office of Water and the Office of Research and Development. | 984 |
| Endocrine Disruptor Screening Program; Final Second List of Chemicals and Substances for Tier 1 Screening | 2013-06-14 | EPA 705-G-2020-3570 | Endocrine Disruptor Screening Program; EDSP; EDSP Policy; EDSP List 2; Chemical Selection | Policy Notice; Description of Final EDSP List 2. This document announces the final second list of 109 chemicals identified for Tier 1 screening under the Endocrine Disruptor Screening Program (EDSP). The EDSP is established under section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA), which requires EPA to develop a chemical screening program using appropriate validated test systems and other scientifically relevant information to determine whether certain substances may have hormonal effects. The second group of chemicals to be tested consists of chemicals that section 408(p) of the FFDCA requires be screened, i.e., pesticide active ingredients and chemicals used as pesticide inert ingredients (also known as other ingredients) and section 1457 of the 1996 amendment to the SDWA. | 989 |
| Endocrine Disruptor Screening Program; Final Policies and Procedures for Screening Safe Drinking Water Act Chemicals | 2013-06-14 | EPA 705-G-2020-3571 | Endocrine Disruptor Screening Program; EDSP; Safe Drinking Water Act; SDWA; Policy | Policy Notice. This document describes EPA's final policies and procedures for requiring Tier 1 screening under the Endocrine Disruptor Screening Program (EDSP) of chemicals for which EPA may issue EDSP test orders pursuant to section 1457 of the Safe Drinking Water Act (SDWA) and section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA). Section 408(p) of the FFDCA directed EPA to develop a chemical screening program using appropriate validated test systems and other scientifically relevant information (OSRI) to determine whether certain chemicals may have hormonal effects. These final policies and procedures supplement the EDSP policies and procedures that were published in the Federal Register on April 15, 2009. | 988 |
| Final Second List of Chemicals for Tier 1 Screening | 2014-06-26 | EPA 705-G-2020-3572 | Endocrine Disruptor Screening Program; EDSP; Policy; Final EDSP List 2; Chemical Selection; Modification | Modification of Final EDSP List 2 noting removal of 2 chemicals. A revised list is provided. On May 22, 2014, EPA removed hydrazine and hydrochlorofluorocarbon (HCFC-22) from the Second List of Chemicals for Screening to allow for further consideration of their physical/chemical properties and/or occurrence in regards to whether these substances are appropriate candidates for testing in the EDSP under Safe Drinking Water Act authority at this time. The U.S. Court of Appeals for the Third Circuit granted EPA’s motion for voluntary partial vacatur and remand regarding these two chemicals. | 998 |
| Endocrine Disruptor Screening Program: Use of High Throughput Assays and Computational Tools | 2015-06-15 | EPA 705-G-2020-3573 | Endocrine Disruptor Screening Program; EDSP; EDSP Policy; High Throughput Assays; HT; Computational Toxicology; Comp Tox | Policy Notice; This document describes how EPA is planning to incorporate an alternative scientific approach to screen chemicals for their ability to interact with the endocrine system. This will improve the Agency's ability to fulfill its statutory mandate to screen pesticide chemicals and other substances for their ability to cause adverse effects by their interaction with the endocrine system. The approach incorporates validated high throughput assays and a computational model and, based on current research, can serve as an alternative for some of the current assays in the Endocrine Disruptor Screening Program (EDSP) Tier 1 battery. EPA has partial screening results for over 1800 chemicals that have been evaluated using high throughput assays and a computational model for the estrogen receptor pathway. In the future, EPA anticipates that additional alternative methods will be available for EDSP chemical screening based on further advancements of high throughput assays and computational models for other endocrine pathways. Use of these alternative methods will accelerate the pace of screening, decrease costs, and reduce animal testing. In addition, this approach advances the goal of providing sensitive, specific, quantitative, and efficient screening using alternative test methods to some assays in the Tier 1 battery to protect human health and the environment. | 986 |
| Endocrine Disruptor Screening Program; Policies and Procedures for Initial Screening | 2009-04-15 | EPA 705-G-2020-3574 | Endocrine Disruptor Screening Program; EDSP; Policy; Screening | Policy Notice; This document describes the policies and procedures EPA generally intends to adopt for initial screening of chemicals under the Endocrine Disruptor Screening Program (EDSP). The EDSP is established under section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA), which requires endocrine screening of all pesticide chemicals and was established in response to growing scientific evidence that humans, domestic animals, and fish and wildlife species have exhibited adverse health consequences from exposure to environmental chemicals that interact with their endocrine systems. | 990 |
| Amphibian Metamorphosis Assay | 2011-10-12 | EPA 705-G-2020-3575 | Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, data evaluation spreadsheet template, DEST | Amphibian Metamorphosis Assay, 890.1100, Data Evaluation Spreadsheet Template. | 958 |
| Androgen Receptor Binding (Rat Prostate) | 2011-09-20 | EPA 705-G-2020-3576 | Endocrine Disruptor Screening Program, EDSP, Androgen Receptor Binding, data evaluation spreadsheet template, DEST | Androgen Receptor Binding, 890.1150, Data Evaluation Spreadsheet Template. | 961 |
| Aromatase (Human Recombinant) | 2011-09-30 | EPA 705-G-2020-3577 | Endocrine Disruptor Screening Program, EDSP, Aromatase, data evaluation spreadsheet template, DEST | Aromatase (Human Recombinant), 890.1200, Data Evaluation Spreadsheet Template | 962 |
| Estrogen Receptor Binding | 2011-09-17 | EPA 705-G-2020-3578 | Endocrine Disruptor Screening Program, EDSP, Estrogen Receptor Binding, data evaluation spreadsheet template, DEST | Estrogen Receptor Binding, 890.1250, Data Evaluation Spreadsheet Template | 993 |
| Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903) | 2011-09-15 | EPA 705-G-2020-3579 | Endocrine Disruptor Screening Program, EDSP, Estrogen Transcriptional Activation (Human Cell Line HeLa-9903), data evaluation spreadsheet template, DEST | Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903), 890.1300, Data Evaluation Spreadsheet Template | 994 |
| Fish Short-Term Reproduction | 2011-09-09 | EPA 705-G-2020-3580 | Endocrine Disruptor Screening Program, EDSP, Fish short-term reproduction, data evaluation spreadsheet template, DEST | Fish Short-Term Reproduction, 890.1350, Data Evaluation Spreadsheet Template | 1000 |
| Hershberger (Rat) | 2011-09-07 | EPA 705-G-2020-3581 | Endocrine Disruptor Screening Program, EDSP, Hershberger (Rat), data evaluation spreadsheet template, DEST | Hershberger, 890.1400, Data Evaluation Spreadsheet Template | 1002 |
| Female Pubertal (Rat) | 2011-09-07 | EPA 705-G-2020-3582 | Endocrine Disruptor Screening Program, EDSP, Female Pubertal (Rat), data evaluation spreadsheet template, DEST | Aromatase (Human Recombinant), 890.1450, Data Evaluation Spreadsheet Template | 996 |
| Male Pubertal (Rat) | 2011-09-07 | EPA 705-G-2020-3583 | Endocrine Disruptor Screening Program, EDSP, Male Pubertal (Rat), data evaluation spreadsheet template, DEST | Male Pubertal (Rat), 890.1500, Data Evaluation Spreadsheet Template. | 1003 |
| Steroidogenesis (Human Cell Line – H295R) | 2011-09-03 | EPA 705-G-2020-3584 | Endocrine Disruptor Screening Program, EDSP, Steroidogenesis (Human Cell Line - H295R), data evaluation spreadsheet template, DEST | Steroidogenesis (Human Cell Line - H295R) 890.1550, Data Evaluation Spreadsheet Template | 1005 |
| Uterotrophic (Rat) | 2011-09-07 | EPA 705-G-2020-3585 | Endocrine Disruptor Screening Program, EDSP, Uterotrophic (Rat), data evaluation spreadsheet template, DEST | Uterotrophic (Rat), 890.1600, Data Evaluation Spreadsheet Template | 1007 |
| Corrections and Clarifications on Technical Aspects of the Endocrine Disruptor Screening Program Tier 1 Assays (OCSPP test guideline series 890) | 2011-03-04 | EPA 705-G-2020-3586 | Endocrine Disruptor Screening Program; EDSP; EDSP Tier 1 Assays; Corrections, Clarifications | In response to questions raised by Test Order recipients and others, e.g., Endocrine Policy Form, CropLife America, the Agency provided a detailed guidance document correcting and clarifying technical aspects of the conduct of Tier 1 assays for the EDSP. (37 p) | 964 |
| Endocrine Disruptor Screening Program Weight-of-Evidence: Evaluating Results of EDSP Tier 1 Screening to Identify the Need for Tier 2 Testing | 2011-09-14 | EPA 705-G-2020-3587 | Weight-of-Evidence, WoE, EDSP, Tier 1 Screening | This guidance document provides basic principles and criteria for using a weight-of-evidence (WoE) approach for evaluation and interpretation of EDSP Tier 1 screening, which includes Tier 1 assay results and other information to identify candidate chemicals for Tier 2 testing. | 985 |
| Endocrine Disruptor Screening Program Universe of Chemicals | 2012-11-01 | EPA 705-G-2020-3588 | Endocrine Disruptor Screening Program; EDSP; EDSP Universe of Chemicals | Guidance on EDSP Universe of Chemicals for potential endocrine disruptor screening and testing | 983 |
| Endocrine Disruptor Screening Program Test Guidelines: Three Tier 2 Non-Mammalian Tests | 2015-08-25 | EPA 705-G-2020-3621 | Endocrine Disruptor Screening Program, EDSP, Tier 2, test guidelines, Larval Amphibian Growth and Development Assay, LAGDA, Medaka Extended One-generation Reproduction Test, MEOGRT, Avian Two-generation Toxicity Test in the Japanese Quail, JQTT | Notice of Availability; EPA is announcing the availability of three Office of Chemical Safety and Pollution Prevention (OCSPP) final test guidelines: Medaka Extended One-generation Reproduction Test (MEOGRT), OCSPP Test Guideline 890.2200; Larval Amphibian Growth and Development Assay (LAGDA), OCSPP Test Guideline 890.2300; and Avian Two-generation Toxicity Test in the Japanese Quail (JQTT), OCSPP Test Guideline 890.2100. These test guidelines are part of a series of test guidelines established by OCSPP for use in testing pesticides and chemical substances. | 981 |
| Endocrine Disruptor Screening Program: Weight-of-Evidence Guidance Document; Availability | 2011-09-28 | EPA 705-G-2020-3622 | Endocrine Disruptor Screening Program; EDSP; Policy; EDSP List 1; Weight-of-Evidence | Notice of Availability; EPA's Endocrine Disruptor Screening Program (EDSP) is announcing the availability of a final guidance document titled, “Weight-of-Evidence: Evaluating Results of EDSP Tier 1 Screening to Identify the Need for Tier 2 Testing.” This weight-of-evidence (WoE) guidance document was revised based on public and peer review comments and existing peer-reviewed EPA guidelines. This guidance document provides basic principles and criteria for application of a WoE approach to evaluate results from the battery of Tier 1 screening assays along with other scientific and technical information relevant to Tier 1 screening to determine whether or not a chemical has the potential to interact with the estrogen, androgen, or thyroid (E, A, or T) hormonal pathways of the endocrine system. The combined results and information will also be used to identify which tests and information may be needed for Tier 2 testing. | 987 |
| Endocrine Disruptor Screening Program (EDSP); Announcing the Availability of the Tier 1 Screening Battery and Related Test Guidelines | 2009-10-21 | EPA 705-G-2020-3623 | Endocrine Disruptor Screening Program, EDSP, Tier 1, test guidelines | Notice of Availability; EPA is announcing the availability of the Endocrine Disruptor Screening Program (EDSP) Tier 1 battery of assays and availability of test guidelines (protocols) for conducting the assays included in the battery. The EDSP was established under section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA), which directed EPA “to develop a screening program. . .to determine whether certain substances may have an effect in humans that is similar to an effect produced by a naturally occurring estrogen, or such other endocrine effect as the Administrator may designate.” Coordinated by EPA, several in vitro and in vivo screening assays were developed, standardized, and validated to identify the potential of a chemical substance to interact with the estrogen, androgen or thyroid (E, A, or T) hormonal systems. Test chemicals that were thought to be potentially interactive as well as non-interactive with the E, A, or T hormonal systems were used to evaluate feasibility of the protocols, relevance of endpoints and reliability of results within and among independent contract laboratories. Subsequent independent peer review of individual assays helped to clarify the strengths and limitations of each assay and define their modes of action involving the E, A, or T hormonal systems within the context of the EDSP Tier 1 battery. EPA submitted a proposed battery of assays to the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) for external peer review in March 2008. Based on the SAP recommendation, which found the proposed battery adequate to begin screening chemicals to detect the potential for interaction with the E, A, or T hormonal systems, | 966 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1100, Amphibian Metamorphosis (Frog) | 2009-10-01 | EPA 740-C-09-002 | Endocrine Disruption Testing; 890.1100; test guideline; Amphibian Metamorphosis (Frog) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 967 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1150, Androgen Receptor Binding (Rat Prostate Cytosol) | 2009-10-01 | EPA 740-C-09-003 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines, 890.1150, Androgen Receptor Binding (Rat Prostate Cytosol) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 968 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1200, Aromatase (Human Recombinant) | 2009-10-01 | EPA 740-C-09-004 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1200; Aromatase (Human Recombinant) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 969 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1250, Estrogen Receptor Binding (Rat Uterine Cytosol) | 2009-10-01 | EPA 740-C-09-005 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1250; Estrogen Receptor Binding (Rat Uterine Cytosol) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 970 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1300, Estrogen Receptor Transcriptional Activation (Human Cell Line (HeLa-9903)) | 2009-10-01 | EPA 740-C-09-006 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1300; Estrogen Receptor Transcriptional Activation (Human Cell Line (HeLa-9903)); ERTA | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 971 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1350, Fish Short-term Reproduction | 2009-10-01 | EPA 740-C-09-007 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines: 890.1350: Fish Short-term Reproduction | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 972 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1400, Hershberger (Rat) | 2009-10-01 | EPA 740-C-09-008 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1400; Hershberger (Rat) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 973 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1450, Female Pubertal (Rat) | 2009-10-01 | EPA 740-C-09-009 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1450; Female Pubertal (Rat) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 974 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1600, Uterotrophic (Rat) | 2009-10-01 | EPA 740-C-09-010 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1600; Uterotrophic (Rat) | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 977 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1550, Steroidogenesis (Human Cell Line - H295R) | 2009-10-01 | EPA 740-C-09-011 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1550; Steroidogenesis (Human Cell Line - H295R) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 976 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1500, Male Pubertal (Rat) | 2009-10-01 | EPA 740-C-09-012 | Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1500; Male Pubertal (Rat) | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 975 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 2 Test Guidelines, 890.2300, Larval Amphibian Growth and Development Assay | 2015-08-01 | EPA 740-C-15-001 | Endocrine Disruption Testing; EDSP Tier 2 Test Guidelines; 890.2300; Larval Amphibian Growth and Development Assay; LAGDA | This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 980 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 2 Test Guidelines, 890.2200, Medaka Extended One Generation Reproduction Test | 2015-08-01 | EPA 740-C-15-002 | Endocrine Disruption Testing; EDSP Tier 2 Test Guidelines; 890.2200; Medaka Extended One Generation Reproduction Test | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 979 |
| Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 2 Test Guidelines, 890.2100, Avian Two-Generation Toxicity Test in the Japanese Quail | 2015-08-01 | EPA 740-C-15-003 | Endocrine Disruption Testing; EDSP Tier 2 Test Guidelines; 890.2100, Avian Two-Generation Toxicity Test in the Japanese Quail; JQTT | The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. | 978 |
Pesticide-related links:
- National list of allowed and prohibited substances for organic crop and livestock production
- Minimum risk pesticides exempted from FIFRA registration under section 25(b)
- Integrated Pest Management Principles
If you are aware of existing guidance which is not referenced on this page or its links, please contact EPA ([email protected]).